Embryo transferEmbryo transfer refers to a step in the process of assisted reproduction in which embryos are placed into the uterus of a female with the intent to establish a pregnancy. This technique (which is often used in connection with in vitro fertilization (IVF), may be used in humans or in animals, in which situations the goals may vary. Embryo transfer can be done at day two or day three, or later in the blastocyst stage, which was first performed in 1984.
EmbryoAn embryo is an initial stage of development of a multicellular organism. In organisms that reproduce sexually, embryonic development is the part of the life cycle that begins just after fertilization of the female egg cell by the male sperm cell. The resulting fusion of these two cells produces a single-celled zygote that undergoes many cell divisions that produce cells known as blastomeres. The blastomeres are arranged as a solid ball that when reaching a certain size, called a morula, takes in fluid to create a cavity called a blastocoel.
Embryo qualityEmbryo quality is the ability of an embryo to perform successfully in terms of conferring a high pregnancy rate and/or resulting in a healthy person. Embryo profiling is the estimation of embryo quality by qualification and/or quantification of various parameters. Estimations of embryo quality guides the choice in embryo selection in in vitro fertilization. In general, embryo profiling for prediction of pregnancy rates focuses mainly on visual profiles and short-term biomarkers including expression of RNA and proteins, preferably in the surroundings of embryos to avoid any damage to them.
Fractal dimensionIn mathematics, a fractal dimension is a term invoked in the science of geometry to provide a rational statistical index of complexity detail in a pattern. A fractal pattern changes with the scale at which it is measured. It is also a measure of the space-filling capacity of a pattern, and it tells how a fractal scales differently, in a fractal (non-integer) dimension. The main idea of "fractured" dimensions has a long history in mathematics, but the term itself was brought to the fore by Benoit Mandelbrot based on his 1967 paper on self-similarity in which he discussed fractional dimensions.
FractalIn mathematics, a fractal is a geometric shape containing detailed structure at arbitrarily small scales, usually having a fractal dimension strictly exceeding the topological dimension. Many fractals appear similar at various scales, as illustrated in successive magnifications of the Mandelbrot set. This exhibition of similar patterns at increasingly smaller scales is called self-similarity, also known as expanding symmetry or unfolding symmetry; if this replication is exactly the same at every scale, as in the Menger sponge, the shape is called affine self-similar.
Fractal curveA fractal curve is, loosely, a mathematical curve whose shape retains the same general pattern of irregularity, regardless of how high it is magnified, that is, its graph takes the form of a fractal. In general, fractal curves are nowhere rectifiable curves — that is, they do not have finite length — and every subarc longer than a single point has infinite length. A famous example is the boundary of the Mandelbrot set. Fractal curves and fractal patterns are widespread, in nature, found in such places as broccoli, snowflakes, feet of geckos, frost crystals, and lightning bolts.
Fractal analysisFractal analysis is assessing fractal characteristics of data. It consists of several methods to assign a fractal dimension and other fractal characteristics to a dataset which may be a theoretical dataset, or a pattern or signal extracted from phenomena including topography, natural geometric objects, ecology and aquatic sciences, sound, market fluctuations, heart rates, frequency domain in electroencephalography signals, digital images, molecular motion, and data science. Fractal analysis is now widely used in all areas of science.
In vitro fertilisationIn vitro fertilisation (IVF) is a process of fertilisation where an egg is combined with sperm in vitro ("in glass"). The process involves monitoring and stimulating a woman's ovulatory process, removing an ovum or ova (egg or eggs) from her ovaries and letting sperm fertilise them in a culture medium in a laboratory. After the fertilised egg (zygote) undergoes embryo culture for 2–6 days, it is transferred by catheter into the uterus, with the intention of establishing a successful pregnancy.
Human embryonic developmentHuman embryonic development, or human embryogenesis, is the development and formation of the human embryo. It is characterised by the processes of cell division and cellular differentiation of the embryo that occurs during the early stages of development. In biological terms, the development of the human body entails growth from a one-celled zygote to an adult human being. Fertilization occurs when the sperm cell successfully enters and fuses with an egg cell (ovum).
Hausdorff dimensionIn mathematics, Hausdorff dimension is a measure of roughness, or more specifically, fractal dimension, that was introduced in 1918 by mathematician Felix Hausdorff. For instance, the Hausdorff dimension of a single point is zero, of a line segment is 1, of a square is 2, and of a cube is 3. That is, for sets of points that define a smooth shape or a shape that has a small number of corners—the shapes of traditional geometry and science—the Hausdorff dimension is an integer agreeing with the usual sense of dimension, also known as the topological dimension.
Minkowski–Bouligand dimensionIn fractal geometry, the Minkowski–Bouligand dimension, also known as Minkowski dimension or box-counting dimension, is a way of determining the fractal dimension of a set in a Euclidean space , or more generally in a metric space . It is named after the Polish mathematician Hermann Minkowski and the French mathematician Georges Bouligand. To calculate this dimension for a fractal , imagine this fractal lying on an evenly spaced grid and count how many boxes are required to cover the set.
Pregnancy ratePregnancy rate is the success rate for getting pregnant. It is the percentage of all attempts that leads to pregnancy, with attempts generally referring to menstrual cycles where insemination or any artificial equivalent is used, which may be simple artificial insemination (AI) or AI with additional in vitro fertilization (IVF). There is no universally accepted definition of the term. Thus in IVF pregnancy rates may be based on initiated treatment cycles, cycles that underwent oocyte retrieval, or cycles where an embryo transfer was performed.
Fractal expressionismFractal expressionism is used to distinguish fractal art generated directly by artists from fractal art generated using mathematics and/or computers. Fractals are patterns that repeat at increasingly fine scales and are prevalent in natural scenery (examples include clouds, rivers, and mountains). Fractal expressionism implies a direct expression of nature's patterns in an art work. The initial studies of fractal expressionism focused on the poured paintings by Jackson Pollock (1912-1956), whose work has traditionally been associated with the abstract expressionist movement.
MicroscopyMicroscopy is the technical field of using microscopes to view objects and areas of objects that cannot be seen with the naked eye (objects that are not within the resolution range of the normal eye). There are three well-known branches of microscopy: optical, electron, and scanning probe microscopy, along with the emerging field of X-ray microscopy. Optical microscopy and electron microscopy involve the diffraction, reflection, or refraction of electromagnetic radiation/electron beams interacting with the specimen, and the collection of the scattered radiation or another signal in order to create an image.
MicroscopeA microscope () is a laboratory instrument used to examine objects that are too small to be seen by the naked eye. Microscopy is the science of investigating small objects and structures using a microscope. Microscopic means being invisible to the eye unless aided by a microscope. There are many types of microscopes, and they may be grouped in different ways.
Preimplantation genetic diagnosisPreimplantation genetic diagnosis (PGD or PIGD) is the genetic profiling of embryos prior to implantation (as a form of embryo profiling), and sometimes even of oocytes prior to fertilization. PGD is considered in a similar fashion to prenatal diagnosis. When used to screen for a specific genetic disease, its main advantage is that it avoids selective abortion, as the method makes it highly likely that the baby will be free of the disease under consideration.
Tubal ligationTubal ligation (commonly known as having one's "tubes tied") is a surgical procedure for female sterilization in which the fallopian tubes are permanently blocked, clipped or removed. This prevents the fertilization of eggs by sperm and thus the implantation of a fertilized egg. Tubal ligation is considered a permanent method of sterilization and birth control. Female sterilization through tubal ligation is primarily used to permanently prevent a patient from having a spontaneous pregnancy (as opposed to pregnancy via in vitro fertilization) in the future.
