Publications related to Compressed Sensing with Probabilistic Measurements: A Group Testing Solution

Peptide-based virucidal drugs

Before the COVID-19 pandemic, viruses were not a major priority for the scientific community. Today, many events have changed the world and the importance of studying viruses, vaccines, and antiviral drugs is fully appreciated. The development of effective ...

EPFL2024

Graph generative deep learning models with an application to circuit topologies

Igor Krawczuk

Modern integrated circuits are tiny yet incredibly complex technological artifacts, composed of millions and billions of individual structures working in unison. Managing their complexity and facilitating their design drove part of the co-evolution of mode ...

EPFL2024

Machine learning method for the classification of the state of living organisms' oscillations

Sandor Kasas, María Inés Villalba

The World Health Organization highlights the urgent need to address the global threat posed by antibiotic-resistant bacteria. Efficient and rapid detection of bacterial response to antibiotics and their virulence state is crucial for the effective treatmen ...

Frontiers Media Sa2024

Community-Aware Group Testing

Suhas Diggavi, Christina Fragouli, Pavlos Nikolopoulos, Sundara Rajan Srinivasavaradhan

Group testing is a technique that can reduce the number of tests needed to identify infected members in a population, by pooling together multiple diagnostic samples. Despite the variety and importance of prior results, traditional work on group testing ha ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2023

Virucidal compositions and use thereof

Francesco Stellacci

The invention relates to substituted cyclodextrin (CD) compounds having C9 to C25 optionally substituted alkyl-based linker groups, which irreversibly inhibit viruses and are useful in the treatment of viral infections. While the compounds of the invention ...

2023

PSGL-1 is an evolutionarily conserved antiviral restriction factor

Chao Jiang, Ying Liu

The arms race between viruses and their hosts shaped the evolutionary history and the genome composition of both parties. Restriction factors are the first-line antiviral effectors encoded by the host genomes and are often conserved through evolution to pr ...

AMER SOC MICROBIOLOGY2023

Seismic Testing of Adjacent Interacting Masonry Structures

Katrin Beyer, Andrea Penna, Igor Tomic

Masonry buildings form building aggregates around the world in historical centers, which developed as the layout of the city or village densified. In these aggregates, adjacent buildings can share structural walls, connected at the interfaces by interlocki ...

2023

On the slip burst amplitude cutoff in dislocation-rich microcrystals

Andreas Mortensen, Luciano Borasi

The plastic deformation of small-scale face-centered cubic metals exhibits intermittent slip burst events that appear on stress-strain curves as sudden strain jumps and/or load drops. These events are generally attributed to the avalanche-like cooperative ...

Pergamon-Elsevier Science Ltd2023

Center-aware Adversarial Augmentation for Single Domain Generalization

Mathieu Salzmann, Zhiye Wang

Domain generalization (DG) aims to learn a model from multiple training (i.e., source) domains that can generalize well to the unseen test (i.e., target) data coming from a different distribution. Single domain generalization (SingleDG) has recently emerge ...

IEEE COMPUTER SOC2023

Viral Genetic Determinants of Prolonged Respiratory Syncytial Virus Infection Among Infants in a Healthy Term Birth Cohort

Thomas Junier, Jacques Fellay, Dylan Lawless, Zhi Ming Xu

Background. Respiratory syncytial virus (RSV) is associated with acute respiratory infection. We sought to identify RSV variants associated with prolonged infection. ...

OXFORD UNIV PRESS INC2023

Comparison of two methods for bioaerosol sampling and characterization in a low-biomass chamber environment

Dusan Licina, Shen Yang, Marouane Merizak, Akila Muthalagu

Bioaerosols are emitted from various sources into the indoor environment and can positively and negatively impact human health. Humans are the major source of bioaerosol emissions indoors, specifically for bacteria. However, efficient sampling to guarantee ...

PERGAMON-ELSEVIER SCIENCE LTD2023

Higher Order Asymptotics: Applications to Satellite Conjunction and Boundary Problems

Soumaya Elkantassi

Higher-order asymptotics provide accurate approximations for use in parametric statistical modelling. In this thesis, we investigate using higher-order approximations in two-specific settings, with a particular emphasis on the tangent exponential model. ...

EPFL2023

Rational Design of Chemically Controlled Antibodies and Protein Therapeutics

Sandrine Madeleine Suzanne Georgeon, Anthony Marchand, Bruno Emanuel Ferreira De Sousa Correia, Pablo Gainza Cirauqui, Li Tang, Sailan Shui, Stéphane Rosset, Lucia Bonati, Leo Scheller

Protein-based therapeutics, such as monoclonal antibodies and cytokines, are important therapies for various pathophysiological conditions such as oncology, autoimmune disorders, and viral infections. However, the wide application of such protein therapeut ...

2023

Traversing Time Dependent Light Fields for Daylight Glare Evaluation

Stephen William Wasilewski

To understand how daylight gives shape and life to architectural spaces, whether existing or imagined, requires quantifying its dynamism and energy. Maintaining these details presents a challenge to simulation and analysis methods that flatten data into di ...

EPFL2023

Phase separation in viral infections

Haohua Li, Christina Ernst

Viruses rely on the reprogramming of cellular processes to enable efficient viral replication; this often requires subcompartmentalization within the host cell. Liquid-liquid phase separation (LLPS) has emerged as a fundamental principle to organize and su ...

ELSEVIER SCI LTD2022

Interlaboratory Test Program to Determine the Precision of the R3 Test Method (ASTM C1897-20) for Measuring Reactivity of Supplementary Cementitious Materials

Karen Scrivener, Ruben Anton Snellings, Diana Londoño Zuluaga

The substitution of portland clinker by supplementary cementitious materials (SCMs) is one of the main avenues for the further decarbonization of cement production. To secure future SCM supplies, generic and performance-related test methods for SCMs are re ...

AMER SOC TESTING MATERIALS2022

Polyanionic Amphiphilic Dendritic Polyglycerols as Broad-Spectrum Viral Inhibitors with a Virucidal Mechanism

Francesco Stellacci, Valeria Cagno, Matteo Gasbarri

Heparin has been known to be a broad-spectrum inhibitor of viral infection for almost 70 years, and it has been used as a medication for almost 90 years due to its anticoagulant effect. This nontoxic biocompatible polymer efficiently binds to many types of ...

American Chemical Society2022

Testing For The Rank Of A Covariance Operator

Victor Panaretos

How can we discern whether the covariance operator of a stochastic pro-cess is of reduced rank, and if so, what its precise rank is? And how can we do so at a given level of confidence? This question is central to a great deal of methods for functional dat ...

INST MATHEMATICAL STATISTICS-IMS2022

Auto-tuning deep forest for shear stiffness prediction of headed stud connectors

Yuqing Liu, Xianlin Wang

The shear stiffness of headed stud connector is a critical parameter for the calculation of deflection and inter-facial shear force for steel-concrete composite structure. Thus, this study presented a promising data-driven model auto-tuning Deep Forest (AT ...

2022

A Baseline Cellular Antiviral State Is Maintained by cGAS and Its Most Frequent Naturally Occurring Variant rs610913

Shuting Xu, Jacques Fellay, Christian Axel Wandall Thorball

Upon recognition of aberrantly located DNA, the innate immune sensor cyclic GMP-AMP synthase (cGAS) activates stimulator of IFN genes (STING)/IFN regulatory factor (IRF)3-driven antiviral responses. In this study, we characterized the ability of a specific ...

American Association of Immunologists ; Oxford University Press2022