Publications related to Mutant aerolysin and uses thereof

Mutant aerolysin and uses thereof

Provided herein are aerolysin polypeptides and/or mutant aerolysin monomers comprising modified amino acid sequences that could have improved substrate analyte, such as (poly)nucleotide and peptide, improved reading properties such as enhanced substrate an ...

2024

Soft Mechanochemistry of Disulfide-Crosslinked Polymer Networks

Zhao Meng

Mechanochemistry harnesses mechanical force to facilitate chemical reactions. Traditionally, the field of polymer mechanochemistry has used methods to activate chemical bonds, which use forces that are larger than those that are required to break a covalen ...

EPFL2024

Near-Room-Temperature Detection of Aromatic Compounds with Inkjet-Printed Plasticized Polymer Composites

Thomas Maeder, Jürgen Brugger, Mohammadmahdi Kiaee

Chemiresistive gas sensors composed of a thermoplastic polymer matrix and conductive fillers offer various advantages for detecting volatile organic compounds (VOCs), including low power consumption due to near-room-temperature operation, high sensitivity, ...

Amer Chemical Soc2024

Architecturally Diverse Polymer Brushes Prepared via Surface-Initiated Atom Transfer Radical Polymerization

Sabrina Sant

Polymer brushes, which are polymers anchored to a solid substrate by one chainend, have the ability to modify the properties of an underlying substrate, offering intriguing features such as enhanced lubrication, reduced friction, colloidal stability, and a ...

EPFL2023

Revealing the Formation Dynamics of Janus Polymer Particles: Insights from Experiments and Molecular Dynamics

Philip Robin Loche

Seeded emulsion polymerization is one of the best-known methods for preparing polymer particles with a controlled size, composition, and shape. It first requires the preparation of seed particles, which are then swollen with additional monomer (the same as ...

Amer Chemical Soc2023

Extraction and controlled functionalization of lignin for materials applications

Stefania Bertella

Lignin is a renewable aromatic polymer that due to its abundance and unique chemical structure is a promising candidate to replace aromatic materials that are currently sourced from fossil oil. The same structure of lignin poses however drawbacks for its v ...

EPFL2022

Engineering of chitosan-based derivatives for non-viral gene delivery

Laura Camille Louise Nicolle

Gene therapy offers the possibility to treat or even cure diseases originating from genetic defects by introducing a therapeutic gene in target cells or correcting the initial defective gene. Amongst different options, non-viral vectors rely on the deliver ...

EPFL2022

Phase behaviour and structure of a model biomolecular condensate

Julian Charles Shillcock

Phase separation of immiscible fluids is a common phenomenon in polymer chemistry, and is recognized as an important mechanism by which cells compartmentalize their biochemical reactions. Biomolecular condensates are condensed fluid droplets in cells that ...

2020

Composition and method for the preparation of sheets, films, fibers, and molded parts

Holger Frauenrath, Daniel Görl, Oguzhan Oguz

The invention describes a composition containing a) a functionalized polymer (10) that comprises at least one polyester segment (13) and at least one, in particular at least two, polymer aggregating segment (11, 12) capable of forming non-covalent bonds ba ...

2020

Functional and Responsive Polymers via Controlled Radical Polymerization

Jian Wang

This Thesis is built around 4 topics, which share in common that they all take advantage of the assets of controlled radical polymerization to either (i) prepare well-defined model systems to address fundamental research questions with regard to the sensit ...

EPFL2020

Electrochemical and morphological engineering of 2D materials for nanopore sensing

Martina Lihter

Nanopores are nanometer-sized holes that were initially proposed for DNA sequencing. Several years ago sequencing was made possible with biological nanopores. However, solid-state nanopores have plenty of advantages to offer compared to their biological co ...

EPFL2020

Structural and Photophysical Templating of Conjugated Polyelectrolytes with Single-Stranded DNA

Ursula Röthlisberger, Polydefkis Diamantis, Natalie Renuka Banerji

A promising approach to influence and control the photophysical properties of conjugated polymers is directing their molecular conformation by templating. We explore here the templating effect of single-stranded DNA oligomers (ssDNAs) on cationic polythiop ...

AMER CHEMICAL SOC2020

Molecular Engineering of Electrode Surfaces for Electrocatalysis

Patrick Eduard Alexa

Electrocatalysts play an important part on the route towards environmental friendly energy sources. They support modern technologies like fuel cells to move further away from the utilization of fossil fuels and the resulting CO2 emission into our atmospher ...

EPFL2020

Swelling-Induced Chain Stretching Enhances Hydrolytic Degrafting of Hydrophobic Polymer Brushes in Organic Media

Harm-Anton Klok, Jian Wang

Hydrophilic polymer brushes grown via surface‐initiated polymerization from silicon oxide surfaces can detach or degraft in aqueous media. Degrafting of these chain end‐tethered polymers is believed to involve hydrolysis of bonds at the polymer–substrate i ...

Wiley-VCH Verlag GmbH2019

Synthesis of Loop Poly(Methyl Methacrylate) Brushes via Chain-End Postpolymerization Modification

Harm-Anton Klok, Piotr Mocny

Polymer brushes are typically densely grafted assemblies of polymer chains that are tethered via one end group to a solid substrate. Anchoring linear polymer chains via both end groups to a surface results in loop-type polymer brushes. Although loop polyme ...

American Chemical Society2019

Composition containing a polymer and an additive

John Christopher Plummer, Holger Frauenrath, Daniel Görl

The invention describes a composition containing a) a functionalized polymer (10) that comprises at least one polymer segment (13) and at least two polymer aggregating segments (11,12) capable of forming non-covalent bonds based on a supramolecular interac ...

2019

Electrochemically polymerized poly (3, 4-phenylenedioxythiophene) as efficient and transparent counter electrode for dye sensitized solar cells

Nikolaos Vlachopoulos, Ulf Anders Hagfeldt, Lin Yang, Jiahuan Zhang, Yan Hao

A new conducting polymer poly (3, 4-phenylenedioxythiophene) is synthesized by the electrochemical polymerization technique with different solvents. We find that solvents used in electrochemical polymerization play important roles for the catalytic activit ...

PERGAMON-ELSEVIER SCIENCE LTD2019

Non equilibrium thermodynamics of protein organization

Alberto Stefano Sassi

Three quarters of the thesis will be devoted to the discussion of non equilibrium systems. We show how certain biological systems cannot be described by standard thermodynamics. The reason is that the energy consumption due to the hydrolysis of ATP imposes ...

EPFL2018

Hybrid laser 3D microprocessing in glass/polymer micromechanical sensor: towards chemical sensing applications

Yves Bellouard

We demonstrate the fabrication of a 3D polymer/glass micromechanical sensor by combining two femtosecond laser direct writing processes: subtractive laser-assisted chemical etching combined with additive two-photon polymerization techniques. In the first s ...

SPIE-INT SOC OPTICAL ENGINEERING2018

Semiaromatic Polyamides and Copolyamides Comprising Kinked Repeating Units

Julien Philippe Cretenoud

The replacement of metals with polymer-based materials is considered to be key to reducing weight, cost, and cycle times in different technological applications, including the automotive and aerospace industries. Semiaromatic polyamides are particularly at ...

EPFL2018