Publication

Implantable glucose sensor : an approach based on a rotating microviscometer combined with a sensitive liquid containing dextran and Concanavalin A

2007
Theses

Abstract

For more than thirty years there has been a high demand for glucose measuring devices to replace the finger pricking methods and to improve the life quality of diabetics. Three approaches are possible, electrochemical, electromagnetic (including optical), and mechanical. We analyzes the feasibility of a glucose sensing technology based on the rheological property of a liquid solution containing Concanavalin A, dextran and glucose which changes its viscosity with the glucose concentration. This sensitive solution is placed into a minimally-invasive subcutaneously implantable sensor. The glucose equilibrium establishes through a selective membrane. The viscosity is measured with a passive, magnetically actuated two-rotor microviscometer. The first rotor measures the local temperature and the second the glucose dependent viscosity of the solution. To miniaturize the microviscometer, a sensitive solution with a low viscosity (

Official source

2007
Theses

Abstract

Official source

Related concepts (28)

Blood glucose monitoring

Blood glucose monitoring is the use of a glucose meter for testing the concentration of glucose in the blood (glycemia). Particularly important in diabetes management, a blood glucose test is typically performed by piercing the skin (typically, via fingerstick) to draw blood, then applying the blood to a chemically active disposable 'test-strip'. The other main option is continuous glucose monitoring (CGM). Different manufacturers use different technology, but most systems measure an electrical characteristic and use this to determine the glucose level in the blood.

Glucose meter

A glucose meter, also referred to as a "glucometer", is a medical device for determining the approximate concentration of glucose in the blood. It can also be a strip of glucose paper dipped into a substance and measured to the glucose chart. It is a key element of glucose testing, including home blood glucose monitoring (HBGM) performed by people with diabetes mellitus or hypoglycemia. A small drop of blood, obtained from slightly piercing a fingertip with a lancet, is placed on a disposable test strip that the meter reads and uses to calculate the blood glucose level.

Continuous glucose monitor

A continuous glucose monitor (CGM) is a device used for monitoring blood glucose on a continual basis by insulin-requiring people with diabetes, e.g. people with type I, type II diabetes or other types of diabetes (e.g. gestational diabetes). A continuous glucose monitor consists of three parts: a small electrode placed under the skin, a transmitter sending readings at regular intervals (ranging from every 1 to 15 min), and a separate receiver.

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