Publication

Needle-free delivery of fluids from compact laser-based jet injector

Christophe Moser, Paul Delrot, Jan Krizek
2020
Journal Articles

Abstract

Jet injection devices have been studied and developed for transdermal drug delivery to avoid the use of needles. Due to bulky actuation mechanisms, they are limited to body areas that are easy to reach such as skin. Here, we demonstrate a thin and long liquid delivery system (e.g.flexible and 30 cm long with 1.2 mm outer diameter) compatible with minimally invasive surgical procedures. The actuation mechanism is based on optical cavitation in a capillary nozzle where a laser pulse is deliveredviaa multimode optical fibre. We show good controllability of the jet speed by varying the actuation laser fluence. The generated jets can successfully penetrate into a 1% agarose gel which is representative of the mechanical properties of several soft body tissues. We further observe that when the system is used in a low laser energy regime (

Official source

https://infoscience.epfl.ch/entities/publication/f942f54d-8161-458e-b8be-880a9207e1be

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Christophe Moser, Paul Delrot, Jan Krizek
2020
Journal Articles

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/f942f54d-8161-458e-b8be-880a9207e1be

About this result

Related concepts (28)

Jet engine

A jet engine is a type of reaction engine, discharging a fast-moving jet of heated gas (usually air) that generates thrust by jet propulsion. While this broad definition may include rocket, water jet, and hybrid propulsion, the term typically refers to an internal combustion air-breathing jet engine such as a turbojet, turbofan, ramjet, or pulse jet. In general, jet engines are internal combustion engines.

Jet aircraft

A jet aircraft (or simply jet) is an aircraft (nearly always a fixed-wing aircraft) propelled by jet engines. Whereas the engines in propeller-powered aircraft generally achieve their maximum efficiency at much lower speeds and altitudes, jet engines achieve maximum efficiency at speeds close to or even well above the speed of sound. Jet aircraft generally cruise most efficiently at about Mach 0.8 () and at altitudes around or more. The idea of the jet engine was not new, but the technical problems involved could not begin to be solved until the 1930s.

Jet propulsion

Jet propulsion is the propulsion of an object in one direction, produced by ejecting a jet of fluid in the opposite direction. By Newton's third law, the moving body is propelled in the opposite direction to the jet. Reaction engines operating on the principle of jet propulsion include the jet engine used for aircraft propulsion, the pump-jet used for marine propulsion, and the rocket engine and plasma thruster used for spacecraft propulsion.

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