Publications related to A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment

Modified capillary number to standardize droplet generation in suction-driven microfluidics

In droplet microfluidic devices with suction-based flow control, the microchannel geometry and suction pressure at the outlet govern the dynamic properties of the two phases that influence the droplet generation. Therefore, it is critical to understand the ...

Springer Heidelberg2024

Strategy to systematically design and deploy the ITER plasma control system: A system engineering and model-based design approach

Richard Pitts, Federico Alberto Alfredo Felici, Federico Pesamosca, Anna Ngoc Minh Trang Vu

The paper details the process of developing the ITER Plasma Control System (PCS), that is, how to design and deploy it systematically, in the most efficient and effective manner. The integrated nature of the ITER PCS, with its multitude of coupled control ...

Elsevier Science Sa2024

RE:SLAB — a load bearing system for open-ended component reuse in building structures

Dario Redaelli, Corentin Jean Dominique Fivet, Jan Friedrich Georg Brütting, Alex-Manuel Muresan, Edisson Xavier Estrella Arcos

The construction industry plays a major role in the high levels of greenhouse gas emissions, resource consumption, and waste generation observed nowadays. Key to the circular economy, structural component reuse arises as a promising solution to divert cons ...

2024

Dynamical simulation via quantum machine learning with provable generalization

Zoë Holmes

Much attention has been paid to dynamical simulation and quantum machine learning (QML) independently as applications for quantum advantage, while the possibility of using QML to enhance dynamical simulations has not been thoroughly investigated. Here we d ...

Amer Physical Soc2024

Oligolithic Cross-task Optimizations across Isolated Workloads

Anastasia Ailamaki, Panagiotis Sioulas, Eleni Zapridou

Enterprises collect data in large volumes and leverage them to drive numerous concurrent decisions and business processes. Their teams deploy multiple applications that often operate concurrently on the same data and infrastructure but have widely differen ...

2024

A semantic model-based systems engineering approach for assessing the operational performance of metal forming process

Dimitrios Kyritsis, Jinzhi Lu, Xiaochen Zheng

Metal Forming is a basic and essential industrial process to provide materials for constructing complex products. To design an efficient metal forming process, the functional requirements and operational performance are two important aspects to be consider ...

Pergamon-Elsevier Science Ltd2024

An aircraft assembly process formalism and verification method based on semantic modeling and MBSE

Dimitrios Kyritsis, Jinzhi Lu, Xiaochen Zheng

The aircraft assembly system is highly complex involving different stakeholders from multiple domains. The design of such a system requires comprehensive consideration of various industrial scenarios aiming to optimize key performance indicators. Tradition ...

Elsevier Sci Ltd2024

A Tunable Self-Offloading Module for Plantar Pressure Regulation in Diabetic Patients

Paolo Germano, Christian Köchli, Yves Perriard, Yoan René Cyrille Civet, Kenny Jeanmonod, Sofia Lydia Ntella, Bhawnath Tiwari

Plantar pressure plays a crucial role in the pathogenesis of foot ulcers among patients with diabetes and peripheral polyneuropathy. Pressure relief is a key requirement for both the prevention and treatment of plantar ulcers. Conventional medical practice ...

2024

Estrogenic, Genotoxic, and Antibacterial Effects of Chemicals from Cryogenically Milled Tire Tread

Florian Frédéric Vincent Breider, Kristin Schirmer, Benoît Jean Dominique Ferrari, Thibault Béranger Masset

Tire and road wear particles (TRWP) contain complex mixtures of chemicals and release them to the environment,and potential toxic effects of these chemicals still need to be characterized. We used a standardized surrogate for TRWP,cryogenically milled tire ...

2024

Lessons Learned from Data-Driven Building Control Experiments: Contrasting Gaussian Process-based MPC, Bilevel DeePC, and Deep Reinforcement Learning

Colin Neil Jones, Loris Di Natale, Yingzhao Lian, Emilio Maddalena, Jicheng Shi

This manuscript offers the perspective of experimentalists on a number of modern data-driven techniques: model predictive control relying on Gaussian processes, adaptive data-driven control based on behavioral theory, and deep reinforcement learning. These ...

2023

Chat2Code: A Chatbot for Model Specification and Code Generation, The Case of Smart Contracts

Shailesh Mishra

The potential of automatic code generation through Model-Driven Engineering (MDE) frameworks has yet to be realized. Beyond their ability to help software professionals write more accurate, reusable code, MDE frameworks could make programming accessible fo ...

Ieee Computer Soc2023

Studies on EU-DEMO 3D coils requirements and conceptual design for error field correction and plasma control

Pierluigi Bruzzone, Hartmut Zohm, Leonardo Pigatto

This work presents the initial studies on the requirements for the design of 3D coils on EU-DEMO. The use of 3D coils in present machines includes two main purposes: the first one is the Error Field Correction (EFC). The EFC aims at minimizing the intrinsi ...

Elsevier Science Sa2023

Modeling high-entropy transition metal alloys with alchemical compression

Michele Ceriotti, Sandip De, Nataliya Lopanitsyna, Guillaume André Jean Fraux

Alloys composed of several elements in roughly equimolar composition, often referred to as high-entropy alloys, have long been of interest for their thermodynamics and peculiar mechanical properties, and more recently for their potential application in cat ...

AMER PHYSICAL SOC2023

A Reuse-Ready Timber Slab-and-Column System for Modular Building Structures

Corentin Jean Dominique Fivet, Jan Friedrich Georg Brütting, Alex-Manuel Muresan, Jonas Warmuth, Edisson Xavier Estrella Arcos

The construction industry is a significant contributor to resource consumption and waste generation. To address this issue, component reuse has been proposed as a way to prevent valuable building elements from being discarded and avoid producing new ones. ...

Curran Associates, Inc.2023

Plasma-Assisted Hybrid Vapour Deposition Technology for Thin Film Fabrication

Caroline Hain

Continuous development of thin film deposition technologies is essential for the fabrication of films that meet the specific requirements of their target applications and working conditions. Therefore, it is necessary to increase the number of accessible a ...

EPFL2023

Human Interactive Robotic Surfaces for Physical Immersion

Fabio Zuliani

Computers have long been augmenting human capabilities and communication, and with emerging technologies, physical immersion in virtual worlds is now attainable. These advancements push the boundaries of human potential, allowing designers, architects, eng ...

EPFL2023

A guide to preclinical evaluation of hydrogel-based devices for treatment of cartilage lesions

Dominique Pioletti, Peyman Karami, Theofanis Stampoultzis, Yanheng Guo

The drive to develop cartilage implants for the treatment of major defects in the musculoskeletal sys-tem has resulted in a major research thrust towards developing biomaterial devices for cartilage repair. Investigational devices for the restoration of ar ...

ELSEVIER SCI LTD2023

Modality-invariant Visual Odometry for Embodied Vision

Amir Roshan Zamir, Roman Christian Bachmann, Marius Reinhard Memmel

Effectively localizing an agent in a realistic, noisy setting is crucial for many embodied vision tasks. Visual Odometry (VO) is a practical substitute for unreliable GPS and compass sensors, especially in indoor environments. While SLAM-based methods show ...

Ieee Computer Soc2023

Interlocking modular microfluidic cooling substrates for future high energy physics experiments

Massimo Angeletti

In high energy physics, semiconductor-based sensors are widely used in particle tracking applications. These sensors are typically glued on low-mass cooling substrates, which guarantee the correct thermal management and, at the same time, minimise their in ...

EPFL2023

Probing proton diffusion as a guide to environmental stability in powder-engineered FAPbI3 and CsFAPbI3 perovskites

Mohammad Khaja Nazeeruddin, Jianxing Xia

Formamidinium lead iodide-based solar cells show promising device reliability. The grain imperfection can be further suppressed by developing powder methodology. The water uptake capability is critical for the stability of a-formamidinium lead triiodide (F ...

ELSEVIER2023