GenomicsGenomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dimensional structural configuration. In contrast to genetics, which refers to the study of individual genes and their roles in inheritance, genomics aims at the collective characterization and quantification of all of an organism's genes, their interrelations and influence on the organism.
Personalized medicinePersonalized medicine, also referred to as precision medicine, is a medical model that separates people into different groups—with medical decisions, practices, interventions and/or products being tailored to the individual patient based on their predicted response or risk of disease. The terms personalized medicine, precision medicine, stratified medicine and P4 medicine are used interchangeably to describe this concept though some authors and organisations use these expressions separately to indicate particular nuances.
Comparative genomicsComparative genomics is a field of biological research in which the genomic features of different organisms are compared. The genomic features may include the DNA sequence, genes, gene order, regulatory sequences, and other genomic structural landmarks. In this branch of genomics, whole or large parts of genomes resulting from genome projects are compared to study basic biological similarities and differences as well as evolutionary relationships between organisms.
File managerA file manager or file browser is a computer program that provides a user interface to manage and folders. The most common performed on files or groups of files include creating, opening (e.g. , playing, editing or printing), renaming, , , and searching for files, as well as modifying s, properties and . Folders and files may be displayed in a hierarchical tree based on their directory structure. Graphical file managers may support copying and moving of files through "copy and paste" and "cut and paste" respectively, as well as through drag and drop, and a separate menu for selecting the target path.
Computer fileIn computing, a computer file is a resource for recording data on a computer storage device, primarily identified by its . Just as words can be written on paper, so can data be written to a computer file. Files can be shared with and transferred between computers and mobile devices via removable media, networks, or the Internet. Different are designed for different purposes. A file may be designed to store an , a written message, a video, a program, or any wide variety of other kinds of data.
SwitzerlandSwitzerland, officially the Swiss Confederation, is a landlocked country located at the confluence of Western, Central and Southern Europe. It is bordered by Italy to the south, France to the west, Germany to the north and Austria and Liechtenstein to the east. Switzerland is geographically divided among the Swiss Plateau, the Alps and the Jura; the Alps occupy the greater part of the territory, whereas most of the country's population of 8.7 million are concentrated on the plateau, which hosts the largest cities and economic centres, including Zürich, Geneva and Basel.
Swiss ReSwiss Reinsurance Company Ltd, commonly known as Swiss Re, is a reinsurance company based in Zürich, Switzerland. It is one of the world's largest reinsurers, as measured by net premiums written. Swiss Re operates through offices in more than 25 countries and was ranked 118th in Forbes Global 2000 leading companies list in 2016. It was also ranked 313th on the Fortune Global 500 in 2015. On 10–11 May 1861, more than 500 houses went up in flames in the town of Glarus, Switzerland.
History of SwitzerlandSince 1848 the Swiss Confederation has been a federal republic of relatively autonomous cantons, some of which have a history of federation that goes back more than 700 years, putting them among the world's oldest surviving republics. The early history of the region is tied to that of Alpine culture. Switzerland was inhabited by the Helvetii, and it came under Roman rule in the 1st century BC. The Gallo-Roman culture was amalgamated with Germanic influence during Late Antiquity, with the eastern part of Switzerland becoming Alemannic territory.
Population genomicsPopulation genomics is the large-scale comparison of DNA sequences of populations. Population genomics is a neologism that is associated with population genetics. Population genomics studies genome-wide effects to improve our understanding of microevolution so that we may learn the phylogenetic history and demography of a population. Population genomics has been of interest to scientists since Darwin. Some of the first methods used for studying genetic variability at multiple loci included gel electrophoresis and restriction enzyme mapping.
Personal genomicsPersonal genomics or consumer genetics is the branch of genomics concerned with the sequencing, analysis and interpretation of the genome of an individual. The genotyping stage employs different techniques, including single-nucleotide polymorphism (SNP) analysis chips (typically 0.02% of the genome), or partial or full genome sequencing. Once the genotypes are known, the individual's variations can be compared with the published literature to determine likelihood of trait expression, ancestry inference and disease risk.
OmicsThe branches of science known informally as omics are various disciplines in biology whose names end in the suffix -omics, such as genomics, proteomics, metabolomics, metagenomics, phenomics and transcriptomics. Omics aims at the collective characterization and quantification of pools of biological molecules that translate into the structure, function, and dynamics of an organism or organisms. The related suffix -ome is used to address the objects of study of such fields, such as the genome, proteome or metabolome respectively.
Swiss mercenariesThe Swiss mercenaries (Reisläufer) were a powerful infantry force constituted by professional soldiers originating from the cantons of the Old Swiss Confederacy. They were notable for their service in foreign armies, especially among the military forces of the Kings of France, throughout the Early Modern period of European history, from the Late Middle Ages into the Renaissance. Their service as mercenaries was at its peak during the Renaissance, when their proven battlefield capabilities made them sought-after mercenary troops.
Economy of SwitzerlandThe economy of Switzerland is one of the world's most advanced and a highly-developed mixed economy. The service sector and Political stability and Economic stability has come to play a significant economic role, particularly the Swiss banking industry and tourism. The economy of Switzerland has ranked first in the world since 2015 on the Global Innovation Index and third in the 2020 Global Competitiveness Report. According to United Nations data for 2016, Switzerland is the third richest landlocked country in the world after Liechtenstein and Luxembourg.
File Allocation TableFile Allocation Table (FAT) is a developed for personal computers and was the default filesystem for MS-DOS and Windows 9x operating systems. Originally developed in 1977 for use on floppy disks, it was adapted for use on hard disks and other devices. The increase in disk drives capacity required three major variants: FAT12, FAT16 and FAT32. FAT was replaced with NTFS as the default file system on Microsoft operating systems starting with Windows XP.
Switzerland during the World WarsDuring World War I and World War II, Switzerland maintained armed neutrality, and was not invaded by its neighbors, in part because of its topography, much of which is mountainous. Germany was a threat and Switzerland built a powerful defense. It served as a "protecting power" for the belligerents of both sides, with a special role in helping prisoners of war. The belligerent states made it the scene for diplomacy, espionage, and commerce, as well as being a safe haven for 300,000 refugees.
File system fragmentationIn computing, file system fragmentation, sometimes called file system aging, is the tendency of a to lay out the contents of non-continuously to allow in-place modification of their contents. It is a special case of data fragmentation. File system fragmentation negatively impacts seek time in spinning storage media, which is known to hinder throughput. Fragmentation can be remedied by re-organizing files and free space back into contiguous areas, a process called defragmentation.
Icon (computing)In computing, an icon is a pictogram or ideogram displayed on a computer screen in order to help the user navigate a computer system. The icon itself is a quickly comprehensible symbol of a software tool, function, or a , accessible on the system and is more like a traffic sign than a detailed illustration of the actual entity it represents. It can serve as an electronic hyperlink or to access the program or data. The user can activate an icon using a mouse, pointer, finger, or voice commands.
