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Publications associées (26)

Seeking the new, learning from the unexpected: Computational models of surprise and novelty in the brain

Alireza Modirshanechi

Human babies have a natural desire to interact with new toys and objects, through which they learn how the world around them works, e.g., that glass shatters when dropped, but a rubber ball does not. When their predictions are proven incorrect, such as whe ...

EPFL2024

Non-invasive stimulation of the human striatum disrupts reinforcement learning of motor skills

Elena Beanato, Esra Neufeld, Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Traian Popa, Pierre Theopistos Vassiliadis, Julie Duqué, Fabienne Windel

Reinforcement feedback can improve motor learning, but the underlying brain mechanisms remain underexplored. In particular, the causal contribution of specific patterns of oscillatory activity within the human striatum is unknown. To address this question, ...

Nature Portfolio2024

Unraveling behavior and cortical signals to guide the development of soft neuroprostheses for auditory restoration and spreading depolarization

Emilie Cornelia Maria Revol

Neuroprostheses have been used clinically for decades, to help restore or preserve brain functions, when pharmaceutical treatments are inefficient. Although great progress in the field has been made over the years to interface with the nervous system, surf ...

EPFL2024

Involvement of prelimbic cortex neurons and related circuits in the acquisition of a cooperative learning by pairs of rats

Maria del Carmen Sandi Perez, Elias Georges Gebara, Ana del Rocio Conde Moro

Social behaviors such as cooperation are crucial for mammals. A deeper knowledge of the neuronal mechanisms underlying cooperation can be beneficial for people suffering from pathologies with impaired social behavior. Our aim was to study the brain activit ...

Springer2024

Neurobiological and metabolic basis of motivation and effort-based decision-making - A human 1H-MRS, fMRI and machine learning study

Arthur Barakat

Motivation is a multifaceted phenomenon that we explore within the framework of decision-making. Through this cognitive process, actions are directed towards specific goals by performing a trade-off between the cost and benefit of an action. The dorsomedia ...

EPFL2024

Variability is the rule: Neurophysiology and contextual visual processing in schizophrenia

Dario Alejandro Gordillo Lopez

Traditionally, studies in schizophrenia research employ a single experimental paradigm. The results typically demonstrate a significant difference between patients and controls. Subsequent studies aim to describe the underlying abnormal mechanism at the ge ...

EPFL2024

QCD worldsheet axion from the bootstrap

Andrea Guerrieri, Victor Gorbenko

The worldsheet axion plays a crucial role in the dynamics of the Yang-Mills confining flux tubes. According to the lattice measurements, its mass is of order the string tension and its coupling is close to a certain critical value. Using the S-matrix Boots ...

Springer Nature2024

Short-term behavior of glass fiber-polymer composite bending-active elastica beam under service load application

Thomas Keller, Landolf-Giosef-Anastasios Rhode-Barbarigos, Tara Habibi

Bending-active elastica beam is a structural configuration that is based on the elastic deformation of an initially straight beam. This deformation occurs when horizontal displacements are applied to a sliding support, causing the beam to bend into an arch ...

2024

Plasticity of sensory representations in the posterior insular cortex during fear learning

Denys Osypenko

Aversively-motivated associative learning allows animals to avoid harm and thus ensures survival. Aversive learning can be studied by the fear learning paradigm, in which an innocuous sensory stimulus like a tone (conditioned stimulus, CS), acquires a nega ...

EPFL2023

A striatal circuit balances learned fear in the presence and absence of sensory cues

Ralf Schneggenburger, Olexiy Kochubey, Michael Kintscher

During fear learning, defensive behaviors like freezing need to be finely balanced in the presence or absence of threat-predicting cues (conditioned stimulus, CS). Nevertheless, the circuits underlying such balancing are largely unknown. Here, we investiga ...

eLIFE SCIENCES PUBL LTD2023

Behavioral outcome of very preterm children at 5 years of age: Prognostic utility of brain tissue volumes at term-equivalent-age, perinatal, and environmental factors

Djalel Eddine Meskaldji, Laura Ioana Gui, Serafeim Loukas

ObjectivePrematurity is associated with a high risk of long-term behavioral problems. This study aimed to assess the prognostic utility of volumetric brain data at term-equivalent-age (TEA), clinical perinatal factors, and parental social economic risk in ...

WILEY2023

Social isolation shortens lifespan through oxidative stress in ants

Alessandro Crespi, Laurent Keller

Social isolation negatively affects health, induces detrimental behaviors, and shortens lifespan in social species. Little is known about the mechanisms underpinning these effects because model species are typically short-lived and non-social. Using coloni ...

Nature Research2023

Mitofusin-2 in nucleus accumbens D2-MSNs regulates social dominance and neuronal function

Bernard Schneider, Maria del Carmen Sandi Perez, Olivia Zanoletti, Jocelin Grosse, Elias Georges Gebara, Marie-Isabelle Guillot de Suduiraut, Simone Astori, Sriparna Ghosal, Eva Ramos Fernandez, Alessandro Chioino

The nucleus accumbens (NAc) is a brain hub regulating motivated behaviors, including social competitiveness. Mitochondrial function in the NAc links anxiety with social competitiveness, and the mitochondrial fusion protein mitofusin 2 (Mfn2) in NAc neurons ...

2023

A biohybrid interaction framework for the integration of robots in animal societies

Francesco Mondada, Daniel Burnier, Vaios Papaspyros, Raphael Cherfan

The collective behavior of animals has been traditionally studied through observation, quantitative models of behavior, and devices of low intelligence. Nowadays, the advancements in the field of robotics allow for closed-loop experiments that occur in rea ...

2023

Curiosity-driven exploration: foundations in neuroscience and computational modeling

Wulfram Gerstner, Alireza Modirshanechi

Curiosity refers to the intrinsic desire of humans and animals to explore the unknown, even when there is no apparent reason to do so. Thus far, no single, widely accepted definition or framework for curiosity has emerged, but there is growing consensus th ...

Cell Press2023

Transcriptomic analysis reveals mitochondrial pathways associated with distinct adolescent behavioral phenotypes and stress response

Maria del Carmen Sandi Perez, Dogukan Hazar Ülgen, Thamyris Silva

Adolescent individuals exhibit great variability in cortical dynamics and behavioral outcomes. The developing adolescent brain is highly sensitive to social experiences and environmental insults, influencing how personality traits emerge. A distinct patter ...

2023

Survey experiments on economic expectations

Andreas Fuster

In this chapter, we discuss field experiments in surveys that are conducted with the purpose of learning about expectation formation and the link between expectations and behavior. We begin by reviewing the rationale for conducting experiments within surve ...

Academic Press2023

Routing and charging game in ride-hailing service with electric vehicles

John Lygeros, Kenan Zhang

This paper studies the routing and charging behaviors of electric vehicles in a competitive ride-hailing market. When the vehicles are idle, they can choose whether to continue cruising to search for passengers, or move a charging station to recharge. The ...

IEEE2023

Thermo-hydro-mechanical behavior of energy barrettes: Field experiments and numerical simulations

Lyesse Laloui, Alessandro Francesco Rotta Loria, Elena Ravera

Over the past two decades, the thermo-hydro-mechanical behavior of earth-contact structures such as piles, walls, slabs, and tunnels, which simultaneously provide structural support and energy supply, has been studied through various field experiments and ...

ELSEVIER2023

Perceived impacts of the Fridays for Future climate movement on environmental concern and behaviour in Switzerland

Claudia Rebeca Binder Signer, Livia Bianca Fritz, Ralph Hansmann

Calling for increased action on climate change, Fridays for Future (FFF) quickly gained momentum around the world and became highly visible through strikes and protests in more than 150 countries. Considering its scale and magnitude, questions about the im ...

2023

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