Publications associées à Chirurgie bariatrique

The effects of time-restricted eating and weight loss on bone metabolism and health: a 6-month randomized controlled trial

Nicholas Edward Phillips, Alexandra Hemmer

Objective This study explored the impact of time-restricted eating (TRE) versus standard dietary advice (SDA) on bone health. Methods Adults with >= 1 component of metabolic syndrome were randomized to TRE (ad libitum eating within 12 hours) or SDA (food p ...

WILEY2022

New Insights Into the Pivotal Role of CREB-Regulated Transcription Coactivator 1 in Depression and Comorbid Obesity

Antoine Timothée Cherix, Jean-René Cardinaux

Depression and obesity are major public health concerns, and there is mounting evidence that they share etiopathophysiological mechanisms. The neurobiological pathways involved in both mood and energy balance regulation are complex, multifactorial and stil ...

FRONTIERS MEDIA SA2022

Probing the Limits of Optical Loss in Ion-Sliced Thin-film Lithium Niobate

Tobias Kippenberg, Mikhail Churaev, Junqiu Liu, Guanhao Huang, Zelin Tan, Di Zhu

We measured the absorption-limited loss at telecommunication wavelengths for thin-film lithium niobate micro-ring resonators using Kerr-calibrated linear response technique. We find the average absorption loss-rate kappa(abs)/2 pi to be 3.65 +/- 0.70 MHz, ...

IEEE2021

Transient Neurovascular Interface for Minimally Invasive Neural Recording and Stimulation

Diego Ghezzi, Philippe Reymond, Laura Ferlauto, Adele Fanelli, Elodie Geneviève Zollinger

Neural interfaces are used to mitigate the burden of traumatic injuries, neurodegenerative diseases, and mental disorders. However, the transient or permanent placement of an interface in close contact with the neural tissue requires invasive surgery, pote ...

Wiley2021

Separating Algorithms From Questions and Causal Inference With Unmeasured Exposures: An Application to Birth Cohort Studies of Early Body Mass Index Rebound

Mats Julius Stensrud, Aaron Leor Sarvet

Observational studies reporting on adjusted associations between childhood body mass index (BMI; weight (kg)/height (m)(2)) rebound and subsequent cardiometabolic outcomes have often not paid explicit attention to causal inference, including definition of ...

2021

Gene-by-environment modulation of lifespan and weight gain in the murine BXD family

Johan Auwerx, Maroun Bou Sleiman, Evan Graehl Williams, Pooja Jha

How lifespan and body weight vary as a function of diet and genetic differences is not well understood. Here we quantify the impact of differences in diet on lifespan in a genetically diverse family of female mice, split into matched isogenic cohorts fed a ...

NATURE PORTFOLIO2021

The Effects of Time-Restricted Eating versus Standard Dietary Advice on Weight, Metabolic Health and the Consumption of Processed Food: A Pragmatic Randomised Controlled Trial in Community-Based Adults

Felix Naef, Nicholas Edward Phillips

Weight loss is key to controlling the increasing prevalence of metabolic syndrome (MS) and its components, i.e., central obesity, hypertension, prediabetes and dyslipidaemia. The goals of our study were two-fold. First, we characterised the relationships b ...

2021

Data integration for the numerical simulation of cardiac electrophysiology

Alfio Quarteroni, Andrea Manzoni, Luca Dede', Stefano Pagani

The increasing availability of extensive and accurate clinical data is rapidly shaping cardiovascular care by improving the understanding of physiological and pathological mechanisms of the cardiovascular system and opening new frontiers in designing thera ...

WILEY2021

Enoxacin induces oxidative metabolism and mitigates obesity by regulating adipose tissue miRNA expression

Johan Auwerx, Tanes Imamura de Lima

MicroRNAs (miRNAs) have been implicated in oxidative metabolism and brown/beige adipocyte identity. Here, we tested whether widespread changes in miRNA expression promoted by treatment with the small-molecule enoxacin cause browning and prevent obesity. En ...

AMER ASSOC ADVANCEMENT SCIENCE2020

Gastric insufflation during cardiopulmonary resuscitation: A study in human cadavers

Introduction: Bag-valve-mask ventilation is the first-line ventilation method during cardiopulmonary resuscitation (CPR). Risks include excessive volume delivery and gastric insufflation, the latter increasing the risk of pneumonia. The efficacy of ventila ...

2020

Weight Loss Directly Influences Intermediate-Term Remission of Diabetes Mellitus After Bariatric Surgery: A Retrospective Case-Control Study

Sina Rüeger

Purpose Roux en Y gastric bypass surgery (RYGB) is an effective therapy for patients with severe obesity. It induces both significant weight loss and rapid improvements of metabolic complications. This study was undertaken to better define the direct role ...

2020

Genome-wide gene-based analyses of weight loss interventions identify a potential role for NKX6.3 in metabolism

Patrick Descombes, Hélène Ruffieux, Sylviane Métairon, Jörg Hager, Nele Gheldof

Hundreds of genetic variants have been associated with Body Mass Index (BMI) through genome-wide association studies (GWAS) using observational cohorts. However, the genetic contribution to efficient weight loss in response to dietary intervention remains ...

Springer2019

Paragangliomas of the spine: a retrospective case series in a national reference French center

Constantin Tuleasca

Introduction Primary paragangliomas (PG) of the spine are extremely rare entities. The present study reviews our experience over a period of 30 years. Methods This is a retrospective, single center, observational study. Patients surgically treated for a sp ...

2020

The role of somatosensory feedback for brain-machine interfaces applications

Tiffany Corbet

Brain-machine interfaces (BMI) based on motor imagery (MI) have emerged as a promising approach to enhance motor skills and restore motor functions. However, the efficacy and efficiency of BMI systems remain limited. The current lack of usability can be ex ...

EPFL2019

Non-invasive, Brain-controlled Functional Electrical Stimulation for Locomotion Rehabilitation in Individuals with Paraplegia

Mohamed Bouri, Solaiman Shokur, Miguel Nicolelis

Spinal cord injury (SCI) impairs the flow of sensory and motor signals between the brain and the areas of the body located below the lesion level. Here, we describe a neurorehabilitation setup combining several approaches that were shown to have a positive ...

Nature Research2019

Motor and cognitive brain circuits of brain-machine interactions

Silvia Marchesotti

Brain-machine interfaces (BMIs) allow the user to control an external device such as a robotic arm, a cursor, or an avatar in a virtual world through the real-time decoding of brain signals and without the involvement of the musculoskeletal system. Althoug ...

EPFL2016

Persistent spatial clusters of high body mass index in a Swiss urban population as revealed by the 5-year GeoCoLaus longitudinal study

Stéphane Joost, Solange Catherine Gaillard, Murielle Bochud, Idris Guessous, Joël Chételat, Fred Michel Paccaud

OBJECTIVE Body mass index (BMI) may cluster in space among adults and be spatially dependent. Whether and how BMI clusters evolve over time in a population is currently unknown. We aimed to determine the spatial dependence of BMI and its 5-year evolution i ...

Bmj Publishing Group2016

Anti-Obesity and Anti-Hyperglycemic Effects of Cinnamaldehyde via altered Ghrelin Secretion and Functional impact on Food Intake and Gastric Emptying

Henry Markram, Julie Meystre, Maurizio Ferdinando Pezzoli, Johannes Le Coutre, Susana Camacho Romero

Cinnamon extract is associated to different health benefits but the active ingredients or pathways are unknown. Cinnamaldehyde (CIN) imparts the characteristic flavor to cinnamon and is known to be the main agonist of transient receptor potential-ankyrin r ...

Nature Publishing Group2015

The role of leptin, melanocortin, and neurotrophin system genes on body weight in anorexia nervosa and bulimia nervosa

Pierre Magistretti, Kai Wang

Objective: Although low weight is a key factor contributing to the high mortality in anorexia nervosa (AN), it is unclear how AN patients sustain low weight compared with bulimia nervosa (BN) patients with similar psychopathology. Studies of genes involved ...

Elsevier2014

A comparison of body mass index spatial dependence among adults and children in a Swiss general population

Stéphane Joost, Idris Guessous

Background: Body mass index (BMI) may cluster in space among adults and be spatially dependent. Whether BMI clusters among children and how adults and children BMI clusters are related remains unknown. We aimed to identify and to compare BMI spatial depend ...

Nature Publishing Group2014