Publications associées à Glande sudoripare

Multisensing wearables for real-time monitoring of sweat electrolyte biomarkers during exercise and analysis on their correlation with core body temperature

Danick Briand, Silvia Demuru, Jaemin Kim, Brince Paul Kunnel, Vincent Gremeaux, Shu Wang

Sweat secreted by the human eccrine sweat glands can provide valuable biomarker information during exercise. Real-time non-invasive biomarker recordings are therefore useful for evaluating the physiological conditions of an athlete such as their hydration ...

2023

Optical Urea Sensing in Sweat for Kidney Healthcare by Sensitive and Selective Non-enhanced Raman Spectroscopy

Christian Enz, Sandro Carrara, Assim Boukhayma, Ata Jedari Golparvar, Mattia Petrelli

Sweat biomarker analysis has attracted much interest in applications ranging from sports to wearable healthcare. Among all the sweat biomolecules, abnormal urea levels have been linked to several complications, particularly renal dysfunction. Here, we repo ...

SPIE-INT SOC OPTICAL ENGINEERING2023

Configurable Organic Electrochemical Transistors with Printed Functional Materials for Multiplexed Sweat Analysis

Silvia Demuru

Monitoring human sweat with wearable biochemical sensors could give insights into the hydration, fatigue, and health status, tracking the variations of biomarkers non-invasively and in real-time. In this field, organic electrochemical transistors (OECTs) a ...

EPFL2022

Wearable systems for measuring sweat rate and methods of using the same

Junrui Zhang, Hoël Maxime Guérin, Fabien Patrick Wildhaber

Presented herein are systems and methods for measuring sweat rate of a subject using a wearable system. A sweat rate may be determined automatically based on one or more signals produced by a wetting sensor module in response to a presence of sweat in the ...

2021

A Wearable Autonomous Colorimetric Sweat Induction System for Sweat Analysis

Silvia Demuru, Brince Paul Kunnel

The wearable biochemical sweat sensor's capability to provide insight into molecular information of health dynamics ignites sweat analysis as a promising noninvasive diagnosis scheme for precision medicine. Here, we demonstrate, for the first time, a color ...

IEEE2021

Printed Iontophoretic‐Integrated Wearable Microfluidic Sweat‐Sensing Patch for On‐Demand Point‐Of‐Care Sweat Analysis

Danick Briand, Silvia Demuru, Brince Paul Kunnel

In recent years, wearable epidermal sweat sensors have received extensive attention owing to their great potential to provide personalized information on the health status of individuals at the molecular level. For on‐demand medical analysis of sweat in se ...

Wiley2021

ANTIGONE: A Programmable Energy-Efficient Current Digitizer for an ISFET Wearable Sweat Sensing System

Maher Kayal, Evgenia Voulgari, François Krummenacher

This article describes the design and the characterization of the ANTIGONE (ANalog To dIGital cONvErter) ASIC (Application Specific Integrated Circuit) built in AMS 0.35 m technology for low dc-current sensing. This energy-efficient ASIC was specifically d ...

2021

Electrochemical determination of nicotine in smokers' sweat

Sandro Carrara, Tugba Kilic

In this work, we report the demonstration of the capability of electrochemical sensors to provide measurements directly on the sweat of volunteers to successfully discriminate heavy smokers by light ones. Since its importance as pharmaceutical treatment-ag ...

ELSEVIER2020

A 3D printed wearable device for sweat analysis

Sandro Carrara, Mahshid Alsadat Padash

This work presents a wearable microfluidic device for sweat analysis. The purpose of this device is to collect sweat from the skin and convey it to the sensor. The device is printed by a 3D printer with Multi-Jet Modelling (MJM) technology using flexible m ...

IEEE2020

Microfluidics by Additive Manufacturing for Wearable Biosensors: A Review

Christian Enz, Sandro Carrara, Mahshid Alsadat Padash

Wearable devices are nowadays at the edge-front in both academic research as well as in industry, and several wearable devices have been already introduced in the market. One of the most recent advancements in wearable technologies for biosensing is in the ...

2020

Sweat monitoring with CMOS compatible technology: ISFETS and beyond

Francesco Bellando

In recent years, sweat has gained increasing attention from the scientific community as a new analyte for health monitoring. The main advantage with respect to the "Gold Standard" for laboratory analysis, i.e. blood, is of course the possibility of perform ...

EPFL2020

Real-Time Multi-Ion Detection in the Sweat Concentration Range Enabled by Flexible, Printed, and Microfluidics-Integrated Organic Transistor Arrays

Danick Briand, Silvia Demuru, Brince Paul Kunnel

Organic electrochemical transistors (OECTs) show remarkable promise as biosensors, thanks to their high signal amplification, simple architecture, and the intrinsic flexibility of the organic material. Despite these properties, their use for real-time sens ...

Wiley2020

Membrane expression of the estrogen receptor ER alpha is required for intercellular communications in the mammary epithelium

Cathrin Brisken, Stéphanie Cagnet

17 beta-Estradiol induces the postnatal development of mammary gland and influences breast carcinogenesis by binding to the estrogen receptor ER alpha. ER alpha acts as a transcription factor but also elicits rapid signaling through a fraction of ER alpha ...

2020

Wearable System for Real-Time Sensing of Biomarkers in Human Sweat

Junrui Zhang

Wearable sweat sensing systems offer non-invasive and real-time bio-data streaming solutions. They open the possibility for continuous monitoring of biomarkers' concentrations as well as their variation in sweat, which is a complementary to current passive ...

EPFL2019

Apparatus for non-invasive sensing of biomarkers in human sweat

Mihai Adrian Ionescu, Erick Antonio Garcia Cordero, Johan Frédéric Longo, Hoël Maxime Guérin, Francesco Bellando, Fabien Patrick Wildhaber

Presented herein are devices for collecting and/or channeling a biofluid (e.g., sweat, tears, saliva) and detecting and/or quantifying one or more biomarkers in the biofluid. The biomarker(s) may include, for example, ions, salts thereof, hormones and/or s ...

2019

A programmable low-power ADC interface for an ISFET sweat sensor used in a wearable multi-sensing system

Maher Kayal, Evgenia Voulgari, François Krummenacher

An application specific integrated circuit (ASIC) named ANTIGONE (ANalog To dIGital cONvErter) was designed in AMS 0.35 mu m technology to interface with four Ion-sensitive field-effect transistor (ISFET) sensors and perform real-time monitoring of some bi ...

IEEE2019

Flexible sweat sensors for non-invasive optimization of lithium dose in psychiatric disorders

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Criscuolo

Lithium is the main mood stabilizer in bipolar disorders and other psychiatric conditions. However, lithium levels in blood must be monitored frequently during therapies because of its narrow therapeutic range. For this reason the patients, whose quality o ...

IEEE2019

Wearable System with Integrated Passive Microfluidics for Real-Time Electrolyte Sensing in Human Sweat

Erick Antonio Garcia Cordero

Wearable systems embodied as patches could offer noninvasive and real-time solutions for monitoring of biomarkers in human sweat as an alternative to blood testing, with applications in personalized and preventive healthcare. Sweat is considered to be a bi ...

EPFL2018

Lab on skin™: 3D monolithically integrated zero-energy micro/nanofludics and FD SOI ion sensitive FETs for wearable multi-sensing sweat applications

Mihai Adrian Ionescu, Erick Antonio Garcia Cordero, Johan Frédéric Longo, Francesco Bellando, Hoël Maxime Guérin, Fabien Patrick Wildhaber

This paper reports a novel fully integrated low power multi-sensing smart system, which, by wafer-level 3D heterogeneous integration of Ion Sensitive Fully Depleted (FD) FETs and SU-8 micro/nanofludics, achieves the first of its kind wearable multi-sensing ...

2017

Analysis of Mammary Gland Phenotypes by Transplantation of the Genetically Marked Mammary Epithelium

Cathrin Brisken, Duje Buric

The mammary gland is the only organ to undergo most of its development after birth and therefore particularly attractive for studying developmental processes. In the mouse, powerful tissue recombination techniques are available that can be elegantly combin ...

2016