Publications associées à Alimentation saine

Innovative Biomarkers for Obesity and Type 1 Diabetes Based on Bifidobacterium and Metabolomic Profiling

Stephan Morgenthaler, Paul Refinetti, Mariya Yuryevna Skvortsova

The role of Bifidobacterium species and microbial metabolites such as short-chain fatty acids (SCFAs) and human milk oligosaccharides in controlling intestinal inflammation and the pathogenesis of obesity and type 1 diabetes (T1D) has been largely studied ...

MDPI2024

A Comparison of Residual-based Methods on Fault Detection

Olga Fink, Gaëtan Michel Frusque

An important initial step in fault detection for complex industrial systems is gaining an understanding of their health condition. Subsequently, continuous monitoring of this health condition becomes crucial to observe its evolution, track changes over tim ...

PHM Society2023

Identifying genetic and dietary modulators of metabolic disorders using systems genetics

Xiaoxu Li

Long-term consumption of lipid-rich foods can contribute to common metabolic diseases and systemic low-grade inflammation. However, dietary responses and the development of non-communicable diseases are shaped by genetic factors and gene-by-environment int ...

EPFL2023

Drivers and Barriers Toward Healthy and Environmentally Sustainable Eating in Switzerland: Linking Impacts to Intentions and Practices

Claudia Rebeca Binder Signer, Ivo Philippe Baur, Ralph Hansmann

Food consumption is among the activities with the most significant environmental impacts, and furthermore contributes to rising health costs. We explored the factors that foster or hinder healthy and sustainable eating in Switzerland. Based on an online ho ...

2022

Cognitive Impairment and Metabolite Profile Alterations in the Hippocampus and Cortex of Male and Female Mice Exposed to a Fat and Sugar-Rich Diet are Normalized by Diet Reversal

João Miguel das Neves Duarte, Adélaïde Alice Mohr

Diabetes impacts on brain metabolism, structure, and function. Alterations in brain metabolism have been observed in obesity and diabetes models induced by exposure to diets rich in saturated fat and/or sugar and have been linked to memory impairment. Howe ...

INT SOC AGING & DISEASE2022

Computational Approaches for Studying Dietary Behaviors with Digital Traces

Kristina Gligoric

Human nutrition and dietary habits shape our health, daily life, societies, the environment, and life on earth in general. However, it remains challenging to understand and attempt to change dietary behaviors using traditional methods due to measurement an ...

EPFL2022

The progressive loss of brain network fingerprints in Amyotrophic Lateral Sclerosis predicts clinical impairment

Enrico Amico, Antonella Romano

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterised by functional connectivity alterations in both motor and extra-motor brain regions. Within the framework of network analysis, fingerprinting represents a reliable approach to ...

ELSEVIER SCI LTD2022

Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans

Johan Auwerx, Richardus Houtkooper

Background: Nicotinamide riboside (NR) is an NAD(+) precursor that boosts cellular NAD(+) concentrations. Preclinical studies have shown profound metabolic health effects after NR supplementation. ...

OXFORD UNIV PRESS2020

Microstructured Fibers for the Production of Food

Véronique Michaud, Francesco Stellacci, Fabien Sorin, Yunpeng Qu, Federica Sordo, Emma-Rose Janecek

Food engineering faces the difficult challenge of combining taste, i.e., tailoring texture and rheology of food matrices with the balanced intake of healthy nutrients. In materials science, fiber suspensions and composites have been developed as a versatil ...

Wiley2019

Neurochemical Modifications in the Hippocampus, Cortex and Hypothalamus of Mice Exposed to Long-Term High-Fat Diet

João Miguel das Neves Duarte, Ana Francisca Leal Silva Soares, Blanca Lizarbe Serra

Metabolic syndrome and diabetes impact brain function and metabolism. While it is well established that rodents exposed to diets rich in saturated fat develop brain dysfunction, contrasting results abound in the literature, likely as result of exposure to ...

2019

A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals

Jacques Fellay, Christian Hammer, Flavia Aurelia Shoko Hodel, Petar Scepanovic

Background The gut microbiome is an important determinant of human health. Its composition has been shown to be influenced by multiple environmental factors and likely by host genetic variation. In the framework of the Milieu Interieur Consortium, a total ...

2019

Transition of the Swiss Phosphorus System towards a Circular EconomyPart 2: Socio-Technical Scenarios

Claudia Rebeca Binder Signer, Jonas Ramon Mehr

A transition towards a circular economy of phosphorus (P) in Switzerland is a multi-faceted challenge as P use is subject to a variety of influencing factors comprising policy interventions, consumption trends, or technological innovations on different spa ...

2018

Detecting overlapping spatial clusters of high sugar-sweetened beverage intake and high body mass index in a general population: a cross-sectional study

Stéphane Joost, Idris Guessous, David Nicolas De Ridder, Beatrice Bacchilega

Background: Evidence suggests that sugar-sweetened beverage (SSB) intake frequency is positively associated with the risk of obesity and diabetes. We aimed to identify populations and areas in high need for interventions to reduce SSB consumption using a f ...

2018

Dietary risk assessment of pesticides from vegetables and drinking water in gardening areas in Burkina Faso

Luiz Felippe De Alencastro, Edouard René Gilbert Lehmann

Vegetables and water samples have been collected around the lake of Loumbila in Burkina Faso. Pesticides resi- dues in food commodities were analyzed using a modified QuEChERS extraction method prior analysis on GC-MS and UPLC-MS/MS of 31 pesticides. Maxim ...

Elsevier2017

Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2

Johan Auwerx, Julien Weber

Sirtuin 3 (Sirt3) is an NAD(+)-dependent mitochondrial deacetylase associated with superoxide dismutase 2 (SOD2)-mediated protection from oxidative stress. We have reported accelerated weight gain and impaired metabolic flexibility in atherosclerotic Sirt3 ...

Springer2016

How Does Circadian Rhythm Impact Salt Sensitivity of Blood Pressure in Mice? A Study in Two Close C57Bl/6 Substrains

Background Mouse transgenesis has provided the unique opportunity to investigate mechanisms underlying sodium kidney reabsorption as well as end organ damage. However, understanding mouse background and the experimental conditions effects on phenotypic rea ...

Public Library of Science2016

Modelling blood flows in the heart: extended Nitsche's method for the treatment of the valves as generalized boundary conditions

Alfio Quarteroni, Luca Dede', Anna Tagliabue

We investigate the blood flow inside idealized left ventricles with prescribed wall movement by defining a formulation of boundary conditions for the Navier-Stokes equations accounting for the valves. Specifically, we consider an extended Nitsche’s method ...

CMBE, Zeta Computational Resources Ltd.2015

Estimation of Blood Pressure and Pulse Transit Time Using Your Smartphone

David Atienza Alonso, Francisco Javier Rincon Vallejos, Srinivasan Murali, Alair Dias Junior

It is widely recognized today that there is an alarming rise of lifestyle-induced chronic diseases (e.g., type II diabetes) in our society. Therefore, a strong need exists for cost-effective and non-invasive devices that can measure blood pressure (BP) to ...

IEEE Computer Society Press2015

An Increased Arginase Activity Is Associated with Corpus Cavernosum Impairment Induced by Hypercholesterolemia

Nikolaos Stergiopoulos, Mikaël Nils Sturny, Fabiana Pereira Da Costa Fraga, Younouss Faye

IntroductionHypercholesterolemia is a prevalent risk factor for the development of erectile dysfunction (ED), mostly due to an increase in oxidative stress and impaired nitric oxide (NO) bioavailability within the penis. Arginase is an enzyme that shares t ...

Wiley-Blackwell2014

An Oral Formulation of Angiotensin-(1-7) Reverses Corpus Cavernosum Damages Induced by Hypercholesterolemia

Nikolaos Stergiopoulos, Fabiana Pereira Da Costa Fraga, Danielle Gomes Passos Silva

Introduction The renin angiotensin system plays a crucial role in erectile function. It has been shown that elevated angiotensin-II levels contribute to the development of erectile dysfunction (ED). Oppositely, angiotensin-(1-7) (Ang-[1-7]) mediates penile ...

Wiley-Blackwell2013