Publications associées à Digestion

Fate and effects of microplastic particles in a periphyton-grazer system

Kristin Schirmer, Ahmed Tlili, Renata Behra

In the aquatic environment, microplastic particles (MP) can accumulate in microbial communities that cover submerged substrata, i.e. in periphyton. Despite periphyton being the essential food source for grazers in the benthic zones, MP transfer from periph ...

Elsevier Sci Ltd2024

Microfluidic devices for automated analysis of ingested bacteria in the Caenorhabditis elegans intestine

Farzad Rezaeianaran

In this thesis, we explored on-chip high-resolution imaging of the fate of intestinal bacteria and bacterial products in Caenorhabditis elegans (C. elegans). In the first part, we carried out high-resolution z-stack fluorescent imaging of Red Fluorescent P ...

EPFL2023

Evaluation of tire tread particle toxicity to fish using rainbow trout cell lines

Kristin Schirmer, Florian Frédéric Vincent Breider, Benoît Jean Dominique Ferrari, Thibault Béranger Masset, Gabrielle Léger

Tire and road wear particles (TRWP) resulting from tire abrasion while driving raise concerns due to their potential contribution to aquatic toxicity. Our study aimed to assess cryogenically milled tire tread (CMTT) particle toxicity, used as a proxy for T ...

2023

Sex Differences in Comorbidity Combinations in the Swedish Population

Patrick Karl Alois Neff

High comorbidity rates, especially mental-physical comorbidity, constitute an increasing health care burden, with women and men being differentially affected. To gain an overview of comorbidity rates stratified by sex across a range of different conditions ...

MDPI2022

Microfluidic culture platforms for C. elegans bacterial interaction and digestion studies at single-organism resolution

Vittorio Viri

Increasing interest in understanding fundamental biological processes, among which aging and nutrition, has led to the study of simple and powerful model organisms, as the round-worm Caenorhabditis elegans (C. elegans). The nematode, selected by Sydney Bre ...

EPFL2021

An In Vivo Microfluidic Study of Bacterial Load Dynamics and Absorption in the C. elegans Intestine

Martinus Gijs, Thomas Lehnert, Vittorio Viri, Maël Arveiler

Caenorhabditiselegans (C. elegans) has gained importance as a model for studying host-microbiota interactions and bacterial infections related to human pathogens. Assessing the fate of ingested bacteria in the worm's intestine is therefore of great interes ...

MDPI2021

Functional kleptoplasts intermediate incorporation of carbon and nitrogen in cells of the Sacoglossa sea slug Elysia viridis

Anders Meibom, Stéphane Laurent Escrig, Charlotte Madeleine Nicole Lekieffre, Michael Kühl

Some sacoglossan sea slugs incorporate intracellular functional algal chloroplasts, a process termed kleptoplasty. "Stolen" chloroplasts (kleptoplasts) can remain photosynthetically active up to several months, contributing to animal nutrition. Whether thi ...

Nature Research2020

Ammonium is the preferred source of nitrogen for planktonic foraminifer and their dinoflagellate symbionts

Anders Meibom, Charlotte Madeleine Nicole Lekieffre, Emmanuelle Geslin

The symbiotic planktonic foraminiferaOrbulina universainhabits open ocean oligotrophic ecosystems where dissolved nutrients are scarce and often limit biological productivity. It has previously been proposed thatO. universameets its nitrogen (N) requiremen ...

ROYAL SOC2020

Anatomy and Physiology of the Digestive Tract of Drosophila melanogaster

Bruno Lemaitre

The gastrointestinal tract has recently come to the forefront of multiple research fields. It is now recognized as a major source of signals modulating food intake, insulin secretion and energy balance. It is also a key player in immunity and, through its ...

GENETICS SOCIETY AMERICA2018

Pediatric Size Swallowable Glass Pill for Digestive Motility Analysis

Catherine Dehollain, Vincent Schlageter, Onur Kazanç

A glass pill for digestive motility tracking with wireless communication is presented. The pill encapsulates three magnetic transmitter coils with a 125 kHz signal, the circuitry required to control the magnetic coil output and the battery. The system prov ...

IEEE2018

Hippo, TGF-beta, and Src-MAPK pathways regulate transcription of the upd3 cytokine in Drosophila enterocytes upon bacterial infection

Bart Deplancke, Yu-Chen Tsai

Cytokine signaling is responsible for coordinating conserved epithelial regeneration and immune responses in the digestive tract. In the Drosophila midgut, Upd3 is a major cytokine, which is induced in enterocytes (EC) and enteroblasts (EB) upon oral infec ...

Public Library of Science2017

Control of growth and gut maturation by &ITHoxD&IT genes and the associated lncRNA &ITHaglr&IT

Denis Duboule, Fabrice Daniel Darbellay, Jozsef Zakany, Anamaria Necsulea

During embryonic development, Hox genes participate in the building of a functional digestive system in metazoans, and genetic conditions involving these genes lead to important, sometimes lethal,growth retardation. Recently, this phenotype was obtained af ...

National Academy of Sciences2017

Oral transfer of chemical cues, growth proteins and hormones in social insects

Laure Menin, Oksana Riba Grognuz, Daniel Ortiz Trujillo, Laurent Keller

Social insects frequently engage in oral fluid exchange trophallaxis between adults, and between adults and larvae. Although trophallaxis is widely considered a food-sharing mechanism, we hypothesized that endogenous components of this fluid might underlie ...

Elife Sciences Publications Ltd2016

Nanotoxicology: 2D analysis in a 3D matrix

Anders Meibom, Louise Helene Soegaard Jensen

Engineered nanoparticles are the fastest growing nanotechnology product, and of increasing environmental concern. Examples include antimicrobial silver nanoparticles, iron oxide particles used in bulk scale for environmental remediation, and micro- and nan ...

2016

How to Architect a Query Compiler

Christoph Koch, Ioannis Klonatos, Amir Shaikhha, Lionel Emile Vincent Parreaux, Mohammad Dashti Rahmat Abadi, Lewis Alexander Brown

This paper studies architecting query compilers. The state of the art in query compiler construction is lagging behind that in the compilers field. We attempt to remedy this by exploring the key causes of technical challenges in need of well founded soluti ...

2016

Clumped isotope fractionation during phosphoric acid digestion of carbonates at 70°C

Marie Estelle Solange Violay

The application of clumped isotopes (Delta(47)) in carbonate minerals as a sensitive temperature proxy in paleo-environments depends on a well-constrained clumped isotope fractionation for the necessary step of phosphoric acid digestion of the carbonate mi ...

Elsevier2016

Live yeasts enhance fibre degradation in the cow rumen through an increase in plant substrate colonization by fibrolytic bacteria and fungi

AimsTo monitor the effect of a live yeast additive on feedstuff colonization by targeted fibrolytic micro-organisms and fibre degradation in the cow rumen. Methods and ResultsAbundance of adhering fibrolytic bacteria and fungi on feedstuffs incubated in sa ...

Wiley-Blackwell2016

Gut physiology mediates a trade-off between adaptation to malnutrition and susceptibility to food-borne pathogens

Bruno Lemaitre, Sveta Chakrabarti, Sylvain Kolly

The animal gut plays a central role in tackling two common ecological challenges, nutrient shortage and food-borne parasites, the former by efficient digestion and nutrient absorption, the latter by acting as an immune organ and a barrier. It remains unkno ...

Wiley-Blackwell2015

Redefining the metabolic landscape through TGF-beta/Activin signaling in Drosophila melanogaster

Wen Bin Chng

Multicellular organisms assess their nutritional state and adapt their metabolic landscape to match their energy demands. In this thesis, we address a longstanding conundrum of how an organism coordinates digestive enzyme expression in response to its nutr ...

EPFL2015

Proteomics of Cerebrospinal Fluid: Throughput and Robustness Using a Scalable Automated Analysis Pipeline for Biomarker Discovery

Loïc Dayon, Martin Kussmann

Cerebrospinal fluid (CSF) is a body fluid of high clinical relevance and an important source of potential biomarkers for brain-associated damages, such as traumatic brain injury and stroke, and for brain diseases, such as Alzheimer's and Parkinson's. Herei ...

Amer Chemical Soc2015