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Publications associées (23)

Molecular Basis for Differential Patterns of Drug Resistance in Influenza N1 and N2 Neuraminidase

Neuraminidase (NA) inhibitors are used for the prevention and treatment of influenza A virus infections. Two subtypes of NA, N1 and N2, predominate in viruses that infect humans, but differential patterns of drug resistance have emerged in each subtype des ...

Amer Chemical Soc2016

Type I Interferon Signaling Prevents IL-1 beta-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue

Alessandra Piersigilli

Type I interferons (IFN-Is) are fundamental for antiviral immunity, but their role in bacterial infections is contradictory and incompletely described. Streptococcus pyogenes activates IFN-I production in innate immune cells, and IFN-I receptor 1 (Ifnar1)- ...

Cell Press2016

Mucosal immune responses following intestinal nematode infection

Nicola Harris

In most natural environments, the large majority of mammals harbour parasitic helminths that often live as adults within the intestine for prolonged periods (1-2years) . Although these organisms have been eradicated to a large extent within westernized hum ...

Wiley-Blackwell2014