Publications associées à Linguistique structurale

A global framework for data-informed bridge examination

Eugen Brühwiler, Numa Joy Bertola, Philippe Schiltz

Examining the performance of an existing bridge requires information on several aspects, such as design choices, material properties, and ongoing degradation processes. It often happens that some critical information is not available. The traditional appro ...

2024

Computational Conceptual Design – Typological Exploration Of Spatial Truss Systems Through Optimization

Corentin Jean Dominique Fivet, Jonas Warmuth, Pierluigi D'Acunto

Exploring a wide range of relevant design options from the outset is crucial for every sound conceptual design process. Optimization techniques are generally employed to generate well-performing structural design options. However, focusing only on performa ...

2023

Structural Basis of the Allosteric Inhibition of Human ABCG2 by Nanobodies

Henning Paul-Julius Stahlberg, Dongchun Ni

ABCG2 is an ATP-binding cassette transporter that exports a wide range of xenobiotic compounds and has been recognized as a contributing factor for multidrug resistance in cancer cells. Substrate and inhibitor interactions with ABCG2 have been extensively ...

Academic Press Ltd- Elsevier Science Ltd2023

Interactive design with optimum matchmaking of reused structural elements – a software implementation

Corentin Jean Dominique Fivet, Jonas Warmuth, Jan Friedrich Georg Brütting

Structural systems are a significant contributor to buildings’ embodied carbon and reusing structural elements in new load-bearing applications is one strategy to reduce this impact. However, integrating this approach into existing design workflows without ...

International Association for Shell and Spatial Structures (IASS)2023

Framework to evaluate the value of monitoring-technique information for structural performance monitoring

Eugen Brühwiler, Numa Joy Bertola

The management of existing civil infrastructure is becoming more crucial as a large share of bridges is approaching their theoretical end of service duration. Structural performance monitoring aims to verify bridge safety at a given time, and it should be ...

2023

Neural substrates of psychosis revealed by altered dependencies between brain activity and white-matter architecture in individuals with 22q11 deletion syndrome

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti, Farnaz Delavari, Karin Bortolin, Emeline Mullier

Background: Dysconnectivity has been consistently proposed as a major key mechanism in psychosis. Indeed, disruptions in large-scale structural and functional brain networks have been associated with psychotic symptoms. However, brain activity is largely c ...

ELSEVIER SCI LTD2022

Structural basis of drug recognition by the multidrug transporter ABCG2

Henning Paul-Julius Stahlberg, Dongchun Ni

ABCG2 is an ATP-binding cassette (ABC) transporter whose function affects the pharmacokinetics of drugs and contributes to multidrug resistance of cancer cells. While its interaction with the endogenous substrate estrone-3-sulfate (E1S) has been elucidated ...

Elsevier2021

Bridge enhancement by means of the UHPFRC Technology: concepts and recent applications

Eugen Brühwiler

Existing bridges in reinforced concrete (RC) need to be enhanced in order to comply with utilization and safety requirements of future use, in particular for higher traffic loads. Such enhancements comprise strengthening to increase the structural resistan ...

Taylor & Francis2021

Validating model-based data interpretation methods for quantification of reserve capacity

Ian Smith, Sai Ganesh Sarvotham Pai

Optimal performance of civil infrastructure is an important aspect of liveable cities. A judicious combination of physics-based models with monitoring data in a validated methodology that accounts for uncertainties is explored in this paper. This methodolo ...

2021

Western listeners detect boundary hierarchy in Indian music: a segmentation study

Martin Alois Rohrmeier, Tudor Popescu

How are listeners able to follow and enjoy complex pieces of music? Several theoretical frameworks suggest links between the process of listening and the formal structure of music, involving a division of the musical surface into structural units at multip ...

NATURE RESEARCH2021

Late Fusion of the Available Lexicon and Raw Waveform-based Acoustic Modeling for Depression and Dementia Recognition

Petr Motlicek, Mathew Magimai Doss, Julian David Fritsch, Subrahmanya Pavankumar Dubagunta

Mental disorders, e.g. depression and dementia, are categorized as priority conditions according to the World Health Organization (WHO). When diagnosing, psychologists employ structured questionnaires/interviews, and different cognitive tests. Although acc ...

ISCA-INT SPEECH COMMUNICATION ASSOC2021

Producing highly complicated materials. Nature does it better

Gervais Chapuis

Through the years, mineralogical studies have produced a tremendous amount of data on the atomic arrangement and mineral properties. Quite often, structural analysis has led to elucidate the role played by minor components, giving interesting insights into ...

2020

Sustainability through reuse: a reconfigurable structural system for residential and office buildings

Corentin Jean Dominique Fivet, Jan Friedrich Georg Brütting, Dario Redaelli, Alex-Manuel Muresan

Current load-bearing systems for buildings rarely have a beneficial end of life. Modular design is a proven solution for revalorizing obsolete structures, but it hardly competes with conventional solutions: the range of future spatial configurations that t ...

World Sustainable Built Environment2020

A Structural Design Methodology for Freeform Timber Plate Structures Using Wood-Wood Connections

Anh Chi Nguyen

Over the past decades, timber has gained popularity as a sustainable building material because of the rising environmental awareness. Furthermore, the resurgence of timber has also been encouraged by the advent of the digital age during the 21st century. T ...

EPFL2020

A New Lighting on Analytical Discrete Sensitivities in the Context of IsoGeometric Shape Optimization

Thibaut Hirschler

Isogeometric shape optimization has been now studied for over a decade. This contribution aims at compiling the key ingredients within this promising framework, with a particular attention to sensitivity analysis. Based on all the researches related to iso ...

2021

A Calculation Method for Interconnected Timber Elements Using Wood-Wood Connections

Yves Weinand, Julien Gamerro, Jean-François Bocquet

Wood-wood connections, widely used in the past, have been progressively replaced by steel fasteners in timber constructions. Currently, they can be manufactured and implemented more efficiently thanks to digital fabrication techniques. In addition, with th ...

2020

A helical inner scaffold provides a structural basis for centriole cohesion

Henning Paul-Julius Stahlberg, Davide Gambarotto, Paul Guichard, Virginie Hamel

The ninefold radial arrangement of microtubule triplets (MTTs) is the hallmark of the centriole, a conserved organelle crucial for the formation of centrosomes and cilia. Although strong cohesion between MTTs is critical to resist forces applied by ciliary ...

2020

The zaojing: review of a unique wooden construction typology

Corentin Jean Dominique Fivet, Jingxian Ye

The zaojing is an ancient Chinese construction system consisting of a dome-shaped assembly of interlocked wooden pieces. These structures are placed above live performance spaces to enhance sound diffusion while creating background scenery. Existing zaojin ...

2020

Force and Shape Control Strategies for Minimum Energy Adaptive Structures

Gennaro Senatore, Arka Prabhata Reksowardojo

This work presents force and shape control strategies for adaptive structures subjected to quasi-static loading. The adaptive structures are designed using an integrated structure-control optimization method developed in previous work, which produces minim ...

2020

Model-Based Occupant Tracking Using Slab-Vibration Measurements

Ian Smith, Yves Sylvain Gilles Reuland, Sai Ganesh Sarvotham Pai, Slah Drira

Sensor-based occupant tracking has the potential to enhance knowledge of the utilization of buildings. Occupancy-tracking strategies using footstep-induced floor vibrations may be beneficial for thermal-load prediction, security enhancement, and care-givin ...

2019