Publications associées à Chromatophore

The Development of Aptamer-Coupled Microelectrode Fiber Sensors (apta-?FS) for Highly Selective Neurochemical Sensing

The selective and sensitive sensing of neurochemicals is essential to decipher in-brain chemistry underlying brain pathophysiology. The recent development of flexible and multifunctional polymer-based fibers has been shown useful in recording and modulatin ...

AMER CHEMICAL SOC2023

A General Framework for Pearlescent Materials

Wenzel Alban Jakob, Ibon Guillen Serrano

The unique and visually mesmerizing appearance of pearlescent materials has made them an indispensable ingredient in a diverse array of applications including packaging, ceramics, printing, and cosmetics. In contrast to their natural counterparts, such syn ...

ASSOC COMPUTING MACHINERY2020

Molecular codes and in vitro generation of hypocretin and melanin concentrating hormone neurons

Hasan Pezeshgi Modarres, Sha Li, Cyril Mikhail

Hypocretin/orexin (HCRT) and melanin concentrating hormone (MCH) neuropeptides are exclusively produced by the lateral hypothalamus and play important roles in sleep, metabolism, reward, and motivation. Loss of HCRT (ligands or receptors) causes the sleep ...

National Academy of Sciences2019

Zebrafish: Housing and husbandry recommendations

This article provides recommendations for the care of laboratory zebrafish (Danio rerio) as part of the further implementation of Annex A to the European Convention on the protection of vertebrate animals used for experimental and other scientific purposes ...

2019

Micro- and nanoscale hierarchical structure of core-shell protein microgels

Giovanni Dietler, Francesco Simone Ruggeri, Raffaele Mezzenga

Protein nanofibrils were first discovered in the context of misfolding and neurodegenerative diseases but have recently been found in naturally occurring functional materials including algal adhesives, bacterial coatings, and even mammalian melanosomes. Th ...

Royal Society of Chemistry2016

Multiple scanning electrochemical microscopy mapping of tyrosinase in micro-contact printed fruit samples on polyvinylidene fluoride membrane

Hubert Girault, Andreas Stephan Lesch, Liang Qiao, Fernando Cortes Salazar, Tzu-En Lin, Alexandra Bondarenko

Herein, we introduce three orthogonal and compatible methods for detecting tyrosinase, a key factor in fruit browning and skin disorders, with high spatial resolution by means of scanning electrochemical microscopy (SECM). All methods are performed subsequ ...

Elsevier2015

Nanostructuring and lattice dynamics of materials by femtosecond lasers

Ahmad Odeh

Physically, the colour of an object is a complex result of its intrinsic surface properties, its transmission properties and its emission properties, all of which contribute to the mix of wavelengths in the light leaving the surface of the object. Structur ...

EPFL2013

Notch Signaling in Pigment Cells and Generation of Mouse Models for Ocular Diseases

Bhushan Sarode

Cellular signaling mediated by Notch receptors results in coordinated regulation of cell growth, survival and differentiation. In melanocytes, Notch signaling is essential for the maintenance of melanocytes and the melanocyte stem cell population. Whereas, ...

EPFL2013

Constitutive gray hair in Mice induced by Melanocyte-specific deletion of c-Myc

Friedrich Beermann, Karine Schouwey, Marzia Armaro

c-Myc is involved in the control of diverse cellular processes and implicated in the maintenance of different tissues including the neural crest. Here we report that c-Myc is particularly important for pigment cell development and homeostasis. Targeting c- ...

2012

A MART-1::Cre transgenic line induces recombination in melanocytes and RPE

Friedrich Beermann, Iraz Toprak Aydin

The number of transgenic mouse lines expressing Cre in either type of pigment cells (melanocytes and retinal pigment epithelium, RPE) is limited, and the available lines do not always offer sufficient specificity. In this study, we addressed this issue and ...

2011

RBP-Jκ-dependent Notch signaling enhances retinal pigment epithelial cell proliferation in transgenic mice

Freddy Radtke, Friedrich Beermann, Iraz Toprak Aydin

The Notch signaling pathway is an ubiquitous cell-cell interaction mechanism, which is essential in controlling processes like cell proliferation, cell fate decision, differentiation or stem cell maintenance. Recent data have shown that Notch signaling is ...

Nature Publishing Group2011

Regulation of DHICA-mediated antioxidation by dopachrome tautomerase: Implication for skin photoprotection against UVA radiation

Friedrich Beermann

Dopachrome tautomerase (Dct) is a critical enzyme in the melanogenesis pathway that isomerizes the intermediate dopachrome to 5,6-dihydroxyindole-2-carboxylic acid (DHICA) and influences the proportion of DHICA monomer incorporated into the 5,6-dihydroxyin ...

Elsevier2010

Analysis of the Pigment Cell Specific Gene MART-1/Melan-A/mlana : Expressional Regulation and Function

Iraz Toprak Aydin

Pigmentation is a complex process that provides many diverse benefits for the organism. Pigment production takes place in the pigment cell lineage in dedicated organelles called melanosomes. Several proteins are specifically recruited to melanosomes for th ...

EPFL2010

Murine Neonatal Melanocytes Exhibit a Heightened Proliferative Response to Ultraviolet Radiation and Migrate to the Epidermal Basal Layer

Friedrich Beermann

Melanocytes respond to UVR not only by producing melanin, but also by proliferating. This is essentially a protective response. We have studied the melanocyte proliferative response after a single UVR exposure to neonatal mice. At 3 days post-UVR in wild-t ...

2009

The Notch signaling pathway : hair graying and pigment cell homeostasis

Karine Schouwey

In animals, pigment cells are essential for coloration, as seen in feathers, fur, skin and eyes. In mammals, neural crest-derived melanocytes constitute the major population of pigment cells that is located mainly in the skin epidermis, as well as in hair ...

EPFL2009

Metalated 1-(p-methoxybenzyl)pyrazole: a structural chameleon

Levente Ondi

When treated with either butyllithium or lithium diisopropylamide, 1-(p-methoxybenzyl)pyrazole undergoes metalation at the exocyclic alpha-position but mutates to the 5-lithio species in the course of a few minutes or hours. Trapping the intermediates with ...

2006