Publications associées à Tachycardie jonctionnelle hisienne

A Computational Study of the Electrophysiological Substrate in Patients Suffering From Atrial Fibrillation

In the context of cardiac electrophysiology, we propose a novel computational approach to highlight and explain the long-debated mechanisms behind atrial fibrillation (AF) and to reliably numerically predict its induction and sustainment. A key role is pla ...

FRONTIERS MEDIA SA2021

ECG-Based Indices to Characterize Persistent Atrial Fibrillation Before and During Stepwise Catheter Ablation

Jean-Marc Vesin, Adrian Luca, Etienne Pruvot

Background: Consistently successful patient outcomes following catheter ablation (CA) for treatment of persistent atrial fibrillation (pers-AF) remain elusive. We propose an electrocardiogram (ECG) analysis designed to (1) refine selection of patients most ...

2021

Outer loop and isthmus in ventricular tachycardia circuits: Characteristics and implications

Alfio Quarteroni, Andrea Manzoni, Luca Dede', Stefano Pagani

BACKGROUND The isthmus of ventricular tachycardia (VT) circuits has been extensively characterized. Few data exist regarding the contribution of the outer loop (OL) to the VT circuit. OBJECTIVE The purpose of this study was to characterize the electrophysi ...

2020

Modular Design and Optimization of Biomedical Applications for Ultra-Low Power Heterogeneous Platforms

David Atienza Alonso, Miguel Peon Quiros, Simone Machetti, Luca Benini, Benoît Walter Denkinger, Elisabetta De Giovanni, Fabio Montagna

In the last years, remote health monitoring is becoming an essential branch of health care with the rapid development of wearable sensors technology. To meet the demand of new more complex applications and ensuring adequate battery lifetime, wearable senso ...

2020

Mapping Biological Current Densities With Ultrafast Acoustoelectric Imaging: Application to the Beating Rat Heart

Pierre-Marc Jean Marie Dansette

Ultrafast acoustoelectric imaging (UAI) is a novel method for the mapping of biological current densities, which may improve the diagnosis and monitoring of cardiac activation diseases such as arrhythmias. This paper evaluates the feasibility of performing ...

Institute of Electrical and Electronics Engineers2019

Experimental study of atrial fibrillation cycle length during rapid atrial septal pacing

Jean-Marc Vesin, Adrian Luca, Sasan Yazdani

Computer model-based simulations have shown that rapid stimulation at 60-100% of atrial fibrillation cycle length (AFCL) from a ring of electrodes located around the septum may induce local capture in both atria for most AF dynamics. The present study aims ...

2017

False arrhythmia alarms reduction in the intensive care unit: a multimodal approach

Jean-Marc Vesin, Sasan Yazdani, Sibylle Fallet

The purpose of this study was to develop algorithms to lower the incidence of false arrhythmia alarms in the ICU using information from independent sources, namely electrocardiogram (ECG), arterial blood pressure (ABP) and photoplethysmogram (PPG). Our app ...

Institute of Physics2016

Nonlinear analysis of right atrial electrograms predicts termination of persistent atrial fibrillation within the left atrium by catheter ablation

Jean-Marc Vesin, Adrian Luca, Andréa Buttu, Etienne Pruvot

The termination of long-standing persistent atrial fibrillation (LS-pAF) can be achieved by stepwise catheter ablation (step-CA) within the left atrium (LA). Our study aims to applying complexity measures derived from nonlinear time series analysis in orde ...

Institute of Physics2016

Atrial fibrillation septal pacing: translation of modelling results

Adrian Luca

Aims: Atrial fibrillation (AF) septal pacing consists of rapid pacing from a ring of electrodes around the atrial septum, leading to local capture of both atria during AF. The present model-based study evaluated the impact of the number of stimulation elec ...

Oxford Univ Press2016

Study of the impact of electrical heterogeneities in the right and left atrium on atrial fibrillation perpetuation

Jean-Marc Vesin, Adrian Luca, Vincent Jacquemet

Introduction: Electrical heterogeneity in the atria has been consistently linked with the initiation and perpetuation of atrial fibrillation (AF). The present model-based study investigated the contribution of action potential duration (APD) heterogeneitie ...

Oxford Univ Press2016

A Multimodal Approach to Reduce False Arrhythmia Alarms in the Intensive Care Unit

Jean-Marc Vesin, Sasan Yazdani, Sibylle Fallet

As part of the 2015 PhysioNet/CinC Challenge, this work aims at lowering the number of false alarms, which are a persistent concern in the intensive care unit. The multimodal database consists of 1250 life-threatening alarm recordings, each categorized as ...

2015

Intermittent Atrial Tachycardia Promotes Repolarization Alternans and Conduction Slowing During Rapid Rates, and Increases Susceptibility to Atrial Fibrillation in a Free-Behaving Sheep Model

Jean-Marc Vesin, Florian Jousset, Etienne Pruvot

Repolarization Alternans and Atrial Remodeling Introduction Paroxysmal atrial fibrillation (AF) may be triggered by intermittent atrial tachycardia, and ultimately lead to persistent AF. However, the mechanisms by which intermittent atrial tachycardia prom ...

Wiley-Blackwell2014

Correlation Dimension as a Measure of the Atrial Fibrillation Capture during Atrial Septal Pacing

Jean-Marc Vesin, Adrian Luca

In the present model-based study, the correlation dimension (D2) was used as a measure of the effectiveness of atrial septal pacing during atrial fibrillation (AF). From ongoing simulated atrial fibrillation, instantaneous transmembrane potential maps were ...

2014

Adaptive frequency tracking of the baseline ECG identifies the site of atrial fibrillation termination by catheter ablation

Jean-Marc Vesin, Andréa Buttu, Jérôme Sébastien Van Zaen, Etienne Pruvot

Multiple organization indices have been used to predict the outcome of stepwise catheter ablation in long-standing persistent atrial fibrillation (AF), however with limited success. Our study aims at developing innovative organization indices from baseline ...

Elsevier Sci Ltd2013

Atrial septal pacing for the termination of atrial fibrillation: study in a biophysical model of human atria

Jean-Marc Vesin, Laurent Renaud Uldry, Lukas Kappenberger

Aims While successful termination by pacing of organized atrial tachycardias has been observed in patients, single site rapid pacing has not yet led to conclusive results for the termination of atrial fibrillation (AF). The purpose of this study was to eva ...

Oxford Univ Press2012

Termination of atrial fibrillation by catheter ablation can be successfully predicted from baseline ECG

Jean-Marc Vesin, Andréa Buttu, Jérôme Sébastien Van Zaen, Etienne Pruvot

Purpose Multiple organization indices (OIs) have been used to predict the outcome of stepwise catheter ablation (step-CA) in long-standing persistent AF (pers-AF), however with limited success. Our study aims at developing innovative OIs from baseline (BL, ...

2012

Tracking of Stepwise Ablation of Persistent Atrial Fibrillation using Synchronization of nearby Electrograms

Jean-Marc Vesin, Andréa Buttu, Etienne Pruvot, Sarah Volorio

Purpose: The timing of bipolar intracardiac electrograms (EGMs) during atrial fibrillation (AF) reflects the dynamics of AF wavelets. The extent of synchronization between EGMs is an indirect measure of AF spatial organization. Our study intends to determi ...

Ieee2011

Characterization of Atrial Repolarization Alternans and Activation Time Kinetics based on Intracardiac Electrograms

Florian Jousset

Interdisciplinary collaboration between physicians and engineers is now widespread in fundamental and clinical studies, due to the increasing complexity of the physiological problems tackled, and the development of novel measurement devices and data analys ...

EPFL2011

Optimizing Local Capture of Atrial Fibrillation by Rapid Pacing: Study of the Influence of Tissue Dynamics

Jean-Marc Vesin, Vincent Jacquemet, Laurent Renaud Uldry, Lukas Kappenberger

While successful termination by pacing of organized atrial tachycardias has been observed in patients, rapid pacing of AF can induce a local capture of the atrial tissue but in general no termination. The purpose of this study was to perform a systematic e ...

Springer Verlag2010

Activity Level of an Atrial Ectopic Focus Observed Through the Equivalent Dipole: a Biophysical Model

Jean-Marc Vesin, Vincent Jacquemet, Mathieu Lemay, Cédric Duchene

Quantifying the role of atrial ectopic foci in the initiation and the maintenance of atrial fibrillation (AF) is a relevant clinical problem. This study aims at assessing the relation between the activity level of an ectopic focus and the complexity of the ...

2009