Publications associées à Context-dependent memory

Bodily self-consciousness as a framework to link sensory information and self-related components of episodic memory: behavioral, neuroimaging, and clinical evidence

The recollection of sensory information and subjective experience related to a personal past event depends on our episodic memory (EM). At the neural level, EM retrieval is linked with the reinstatement of hippocampal activity thought to recollect the sens ...

EPFL2023

An insular cortex - lateral amygdala network in fear learning

Shriya Palchaudhuri

Animals are capable of evaluating sensory cues for possible threats and adapting their behaviours accordingly. Fear learning is an evolutionarily conserved behaviour crucial for animal survival, during which sensory percepts with a negative reinforcing qua ...

EPFL2022

Where does the engram come from? Study of prefrontal cortex inputs during memory consolidation

Lucie Pauline Dixsaut

The formation and storage of memories has been under deep investigation for several decades. Nevertheless, the precise contribution of each brain region involved in this process and the interplay between them across memory consolidation is still largely de ...

EPFL2022

Genetic selection for low glucocorticoid responsiveness recapitulates PTSD-related phenotypes: a behavioral, neuroimaging and sleep-physiology study

Silvia Monari

Humans show inter-individual differences in vulnerability to develop post-traumatic stress disorder (PTSD) following exposure to trauma. Several critical biobehavioral features have been consistently described in PTSD patients, including blunted cortisol l ...

EPFL2022

Low-Cost Side-Channel Secure Standard 6T-SRAM-Based Memory With a 1% Area and Less Than 5% Latency and Power Overheads

Robert Giterman

Side-channel attacks constitute a concrete threat to IoT systems-on-a-chip (SoCs). Embedded memories implemented with 6T SRAM macrocells often dominate the area and power consumption of these SoCs. Regardless of the computational platform, the side-channel ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2021

The influence of anodal transcranial direct current stimulation over the right auditory cortex on interference effects in memory for melodies

Steffen Alexander Herff

The study investigates how transcranial direct current stimulation (tDCS) over the auditory cortex (AC) modulates memory for melodies under different noise conditions, whilst also considering cumulative disruptive interference effects. Forty-one participan ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2021

The mysteries of remote memory

Johannes Gräff, Zimbul Albo

Long-lasting memories form the basis of our identity as individuals and lie central in shaping future behaviours that guide survival. Surprisingly, however, our current knowledge of how such memories are stored in the brain and retrieved, as well as the dy ...

2018

Context-Aware Attention Mechanism for Speech Emotion Recognition

Philip Neil Garner, Gaétan Ramet

In this work, we study the use of attention mechanisms to enhance the performance of the state-of-the-art deep learning model in Speech Emotion Recognition (SER). We introduce a new Long Short-Term Memory (LSTM)-based neural network attention model which i ...

IEEE2018

The dopaminergic VTA - basal amygdala projection contributes to signal aversive state in fear memory

Wei Tang

Dopamine released from midbrain neurons is an important neuromodulatory signal during associative learning in many forebrain circuits. One model of associative learning is auditory cued fear learning, during which an innocuous sensory percept like a tone ( ...

EPFL2018

In the pursuit of the fear engram: identification of neuronal circuits underlying the treatment of anxiety disorder

Ossama Mohamed Salah El-Dien El-Sayed Ibrahim Khalaf

Fear and other anxiety disorders are extraordinarily robust and difficult to treat. Among the most effective treatments for anxiety disorders are exposure-based therapies, during which a patient is repeatedly confronted with the originally fear-eliciting s ...

EPFL2017

Isoform switching of steroid receptor co-activator-1 attenuates glucocorticoid-induced anxiogenic amygdala CRH expression

Maladaptive glucocorticoid effects contribute to stress-related psychopathology. The glucocorticoid receptor (GR) that mediates many of these effects uses multiple signaling pathways. We have tested the hypothesis that manipulation of downstream factors (' ...

Nature Publishing Group2016

Astrocytic beta(2)-adrenergic receptors mediate hippocampal long-term memory consolidation

Pierre Magistretti, Sylvain Eric Lengacher, Virginia Gao

Emotionally relevant experiences form strong and long-lasting memories by critically engaging the stress hormone/neurotransmitter noradrenaline, which mediates and modulates the consolidation of these memories. Noradrenaline acts through adrenergic recepto ...

National Academy of Sciences2016

Viability evolutionary algorithms and applications to neuroscience and biology

Andrea Maesani

Evolutionary algorithms are heuristic methods that operate on a population of individuals, which represent candidate solutions to optimization problems. Individuals with better quality, or fitness, are reproduced at a higher rate than less fit individuals ...

EPFL2015

Learning-Induced Gene Expression in the Hippocampus Reveals a Role of Neuron-Astrocyte Metabolic Coupling in Long Term Memory

Pierre Magistretti, Igor Allaman, Gabriele Grenningloh, Sylvain Eric Lengacher, Monika Tadi

We examined the expression of genes related to brain energy metabolism and particularly those encoding glia (astrocyte)-specific functions in the dorsal hippocampus subsequent to learning. Context-dependent avoidance behavior was tested in mice using the s ...

Public Library of Science2015

Connexin 30 sets synaptic strength by controlling astroglial synapse invasion

Graham Knott, Nicole Déglon

Astrocytes play active roles in brain physiology by dynamic interactions with neurons. Connexin 30, one of the two main astroglial gap-junction subunits, is thought to be involved in behavioral and basic cognitive processes. However, the underlying cellula ...

Nature Publishing Group2014

A key role for nectin-1 in the ventral hippocampus in contextual fear memory

Maria del Carmen Sandi Perez, Jocelin Grosse, Michael van der Kooij, Martina Fantin

Nectins are cell adhesion molecules that are widely expressed in the brain. Nectin expression shows a dynamic spatiotemporal regulation, playing a role in neural migratory processes during development. Nectin-1 and nectin-3 and their heterophilic trans-int ...

Public Library of Science2013

Membrane potential correlates of sensory perception in mouse barrel cortex

Carl Petersen, Yves Emile Alfred Kremer, Shankar Sachidhanandam, Varun Sreenivasan, Alexandros Kyriakatos

Neocortical activity can evoke sensory percepts, but the cellular mechanisms remain poorly understood. We trained mice to detect single brief whisker stimuli and report perceived stimuli by licking to obtain a reward. Pharmacological inactivation and optog ...

Nature Publishing Group2013

The temporal dynamics of feature integration for color and form

Michael Herzog

When two visual stimuli are presented in rapid succession only one fused image is perceived. For example, a red disk followed by a green disk is perceived as a single yellow disk (e.g., Efron, Perc Psychophys, 1973). For two verniers that last 30ms each, i ...

Association for Research in Vision and Ophthalmology2012

Electrical neuroimaging of memory discrimination based on single-trial multisensory learning

Micah Murray, Antonia Thelen

Multisensory experiences influence subsequent memory performance and brain responses. Studies have thus far concentrated on semantically congruent pairings, leaving unresolved the influence of stimulus pairing and memory sub-types. Here, we paired images w ...

Elsevier2012

Lack of cyclin D2 impairing adult brain neurogenesis alters hippocampal-dependent behavioral tasks without reducing learning ability

Maria del Carmen Sandi Perez

The exact function of the adult brain neurogenesis remains elusive, although it has been suggested to play a role in learning and memory processes. In our studies, we employed cyclin D2 gene knockout (cD2 KO) mice showing impaired neurogenesis as well as d ...

2012