Vibrio

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Publications associées (27)

Neighbor predation linked to natural competence fosters the transfer of large genomic regions in Vibrio cholerae

Melanie Blokesch, Nicolas Jean Philippe Guex, Sandrine Stutzmann, Christian Iseli, Candice Stoudmann, Noémie Matthey

Natural competence for transformation is a primary mode of horizontal gene transfer. Competent bacteria are able to absorb free DNA from their surroundings and exchange this DNA against pieces of their own genome when sufficiently homologous. However, the ...

2019

Mechanisms of DNA Uptake by Naturally Competent Bacteria

Melanie Blokesch

Transformation is a widespread mechanism of horizontal gene transfer in bacteria. DNA uptake to the periplasmic compartment requires a DNA-uptake pilus and the DNA-binding protein ComEA. In the gram-negative bacteria, DNA is first pulled toward the outer m ...

2019

Eco-Evolutionary Dynamics Linked to Horizontal Gene Transfer in Vibrios

Melanie Blokesch, Frédérique Marie Jeanne Le Roux

Vibrio is a genus of ubiquitous heterotrophic bacteria found in aquatic environments. Although they are a small percentage of the bacteria in these environments, vibrios can predominate during blooms. Vibrios also play important roles in the degradation of ...

2018

Molecular insights into Vibrio cholerae’s intra-amoebal host-pathogen interactions

Graham Knott, Melanie Blokesch, Sandrine Stutzmann, Candice Stoudmann, Catherine Maclachlan, Natalia Carolina Drebes Dorr, Charles Ulric V Van der Henst, Tiziana Scrignari, Audrey Sophie Vanhove

Vibrio cholerae, which causes the diarrheal disease cholera, is a species of bacteria commonlyfound in aquatic habitats. Within such environments, the bacterium must defend itselfagainst predatory protozoan grazers. Amoebae are prominent grazers, withAcant ...

Nature Research2018

Visualizing chemical transport from extracellular symbionts into squid host tissues using NanoSIMS

Stéphanie Kéren Cohen

Chemical communication is the basis of host-microbe interaction. Insights into this communication will provide a deeper understanding of the mechanisms that govern these complex associations, in beneficial as well as pathogenic contexts. In this dissertati ...

EPFL2017

The DNA-Uptake Process of Naturally Competent Vibrio cholerae

Melanie Blokesch, Noémie Matthey

The sophisticated DNA-uptake machinery used during natural transformation is still poorly characterized, especially in Gram-negative bacteria where the transforming DNA has to cross two membranes as well as the peptidoglycan layer before entering into the ...

Elsevier2016

Independent Regulation of Type VI Secretion in Vibrio cholerae by TfoX and TfoY

Melanie Blokesch, Sandrine Stutzmann, Noémie Matthey, Lisa Christina Metzger, Tiziana Scrignari, Charles Ulric V Van der Henst

Type VI secretion systems (T6SSs) are nanomachines used for interbacterial killing and intoxication of eukaryotes. Although Vibrio cholerae is a model organism for structural studies on T6SSs, the underlying regulatory network is less understood. A recent ...

Elsevier2016

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