Publications associées à Neural Darwinism

Subcortical correlates of consciousness with human single neuron recordings

Olaf Blanke, Fosco Bernasconi, Nathan Quentin Faivre, Michael Eric Anthony Pereira

Subcortical brain structures such as the basal ganglia or the thalamus are involved in regulating motor and cognitive behavior. However, their contribution to perceptual consciousness is still unclear, due to the inherent difficulties of recording subcorti ...

2024

Me, Myself, and I: Neural Activity for Self versus Other across Development

Solange Noémie Jeanne Denervaud, Paola Zanchi

Although adults and children differ in self-vs.-other perception, a developmental perspective on this discriminative ability at the brain level is missing. This study examined neural activation for self-vs.-other in a sample of 39 participants spanning fou ...

MDPI2023

Plasticity of sensory representations in the posterior insular cortex during fear learning

Denys Osypenko

Aversively-motivated associative learning allows animals to avoid harm and thus ensures survival. Aversive learning can be studied by the fear learning paradigm, in which an innocuous sensory stimulus like a tone (conditioned stimulus, CS), acquires a nega ...

EPFL2023

Tissue clearing applications in memory engram research

Johannes Gräff, Kwok Yui Reymond Yip

A memory engram is thought to be the physical substrate of the memory trace within the brain, which is generally depicted as a neuronal ensemble activated by learning to fire together during encoding and retrieval. It has been postulated that engram cell e ...

FRONTIERS MEDIA SA2023

Uncovering the neural encoding of behavior in the adult Drosophila motor system

Chin-Lin Chen

One of the most important goals in neuroscience research has always been to understand how animals control their behavior. However, the long focus on the role of brain neurons in behavioral control might be missing the full story. In fact, brain-wide fluct ...

EPFL2022

Epigenetic plasticity as a signature for memory allocation

Giulia Santoni

Long-lasting memories are stored in a small set of neurons scattered throughout the brain, so-called engram cells. To define a stable engram each region of the brain involved in memory storage recruits between 5 and 20 percent of excitatory neurons. In par ...

EPFL2022

Uncovering the neural substrates of communication between the brain and ventral nerve cord in Drosophila melanogaster (italic)

Florian Aymanns

Despite a long history of research in motor control, the exact mechanism of how the brain communicates with the the invertebrate ventral nerve cord (VNC) and the vertebrate spinal cord on a single neuron basis remains largely elusive. Drosophila melanogast ...

EPFL2022

The perspectives of mapping and monitoring of the sense of self in neurosurgical patients

Olaf Blanke, Bruno Herbelin, Hyeongdong Park, Sophie Jacqueline Andrée Betka, Pavo Orepic, Sixto Luis Alcoba Banqueri, Giannina Rita Iannotti

Surgical treatment of tumors, epileptic foci or of vascular origin, requires a detailed individual pre-surgical workup and intra-operative surveillance of brain functions to minimize the risk of post-surgical neurological deficits and decline of quality of ...

SPRINGER WIEN2021

Evidence accumulation relates to perceptual consciousness and monitoring

Olaf Blanke, Fosco Bernasconi, Nathan Quentin Faivre, Mi Xue Tan, Michael Eric Anthony Pereira, Wenwen Chang

A fundamental scientific question concerns the neural basis of perceptual consciousness and perceptual monitoring resulting from the processing of sensory events. Although recent studies identified neurons reflecting stimulus visibility, their functional r ...

Nature Research2021

Deconvolution of Sustained Neural Activity From Large-Scale Calcium Imaging Data

Dimitri Nestor Alice Van De Ville, Fikret Isik Karahanoglu, Younes Farouj

Recent technological advances in light-sheet microscopy make it possible to perform whole-brain functional imaging at the cellular level with the use of Ca2+ indicators. The outstanding spatial extent and resolution of this type of data open unique opportu ...

Institute of Electrical and Electronics Engineers2020

Breathing is coupled with voluntary action and the cortical readiness potential

Olaf Blanke, Oliver Alan Kannape, Hyeongdong Park, Coline Barnoud, Henri Dan Trang

Voluntary action is a fundamental element of self-consciousness. The readiness potential (RP), a slow drift of neural activity preceding self-initiated movement, has been suggested to reflect neural processes underlying the preparation of voluntary action; ...

Nature Research2020

Development and application of dynamic functional connectivity methods to elucidate the neural underpinnings of human behaviour with functional magnetic resonance imaging

Thomas William Arthur Bolton

Human behaviour is exquisitely complex, because it is staggeringly multi-facetted and subtly varies across individuals. Characterising its yet incompletely understood underlying biological mechanisms has profound clinical implications. Here, our goal was t ...

EPFL2020

First-person body view modulates the neural substrates of episodic memory and autonoetic consciousness: A functional connectivity study

Dimitri Nestor Alice Van De Ville, Olaf Blanke, Bruno Herbelin, Thomas William Arthur Bolton, Nathan Quentin Faivre, Baptiste Gauthier, Robin Mange, Florian Lance, Lucie Bréchet

Episodic memory (EM) is classically conceived as a memory for events, localized in space and time, and characterized by autonoetic consciousness (ANC) allowing to mentally travel back in time and subjectively relive an event. Building on recent evidence th ...

2020

Tapping into Multi-Faceted Human Behavior and Psychopathology Using fMRI Brain Dynamics

Dimitri Nestor Alice Van De Ville, Thomas William Arthur Bolton, Maria Giulia Preti, Elenor Morgenroth

Human behavior comprises many aspects that stand out by their dynamic nature. To quantify its neural underpinnings, time-resolved fMRI methods have blossomed over the past decade. In this review we conceptually organize a broad repertoire of dynamic analyt ...

2020

Towards everyday brain-computer interfacing through decoding visual cognition

Ruslan Aydarkhanov

Decoding visual cognition from non-invasive measurements of brain activity has shown valuable applications. Vision-based Brain-Computer Interfaces (BCI) systems extend from spellers to database search and spatial navigation. Despite the high performance of ...

EPFL2020

Dynamic spatiotemporal patterns of brain connectivity reorganize across development

Alessandra Griffa, Patric Hagmann, Marie Schaer, Emeline Mullier

Late human development is characterized by the maturation of high-level functional processes, which rely on reshaping of white matter connections, as well as synaptic density. However, the relationship between the whole-brain dynamics and the underlying wh ...

MIT PRESS2020

Prefrontal High Gamma in ECoG Tags Periodicity of Musical Rhythms in Perception and Imagination

Steffen Alexander Herff

Rhythmic auditory stimuli are known to elicit matching activity patterns in neural populations. Furthermore, recent research has established the particular importance of high-gamma brain activity in auditory processing by showing its involvement in auditor ...

2020

Coupling Inner and Outer Body for Self-Consciousness

Olaf Blanke, Hyeongdong Park

Although recent studies on self-consciousness emphasized the importance of bodily processing and multisensory integration, such research has focused solely on bodily signals originating from the outside of the body (i.e., exteroceptive bodily signals) or i ...

2019

Bold Signal Deconvolution Under Uncertain HÆModynamics: A Semi-Blind Approach

Dimitri Nestor Alice Van De Ville, Fikret Isik Karahanoglu, Younes Farouj

The investigation of spontaneous and evoked neuronal activity from functional Magnetic Resonance Imaging (fMRI) data has come to play a significant role in deepening our understanding of brain function. As this research trend continues, activity detection ...

IEEE2019

Capturing the spatiotemporal dynamics of self-generated, task-initiated thoughts with EEG and fMRI

Rolf Gruetter, João Pedro Forjaco Jorge, Lucie Bréchet

The temporal structure of self-generated cognition is a key attribute to the formation of a meaningful stream of consciousness. When at rest, our mind wanders from thought to thought in distinct mental states. Despite the marked importance of ongoing menta ...

2019