Publications associées à Désarmement nucléaire

Comprehensive analysis of the circadian nuclear and cytoplasmic transcriptome in mouse liver

Felix Naef, Cédric Gobet, Benjamin Dieter Weger, Clémence Yumie Syloun Hurni

In eukaryotes, RNA is synthesised in the nucleus, spliced, and exported to the cytoplasm where it is translated and finally degraded. Any of these steps could be subject to temporal regulation during the circadian cycle, resulting in daily fluctuations of ...

PUBLIC LIBRARY SCIENCE2022

Tuning the Size and Geometry of Heteroleptic Coordination Cages by Varying the Ligand Bent Angle

Rosario Scopelliti, Kay Severin, Farzaneh Fadaei Tirani, Rujin Li

Spherical assemblies of the type [PdnL2n]2n+ can be obtained from PdII salts and curved N-donor ligands, L. It is well established that the bent angle, α, of the ligand is a decisive factor in the self-assembly process, with larger angles leading to comple ...

2021

Synthesis, reactivity, and environmental relevance of uranyl(V) complexes

Radmila Faizova

Knowledge of fundamental chemical properties of all environmentally relevant uranium species is essential to understand environmental uranium mobility and develop novel remediation strate-gies. A myriad of uranium(VI) and uranium(IV) compounds has been stu ...

EPFL2020

A risk-based multi-level stress test methodology: application to six critical non-nuclear infrastructures in Europe

Anton Schleiss, José Pedro Gamito de Saldanha Calado Matos, Daniela Rodrigues

Recent natural disasters that seriously affected critical infrastructure (CI) with significant socio-economic losses and impact revealed the need for the development of reliable methodologies for vulnerability and risk assessment. In this paper, a risk-bas ...

2020

cGAS regulation and activity during genotoxic stress

Sélène-Véronique Glück

The innate immune system has evolved to detect pathogens through germlineencoded pattern recognition receptors (PRRs). Nucleic acid sensors, a defined class of PRRs, bind to microbial and viral nucleic acids and trigger the production of type I interferons ...

EPFL2020

Probing strongly hybridized nuclear-electronic states in a model quantum ferromagnet

Henrik Moodysson Rønnow, Giovanni Boero, Peter Babkevich, Julian Piatek, Ivan Kovacevic

We present direct local-probe evidence for strongly hybridized nuclear-electronic spin states of an Ising ferromagnet LiHoF4 in a transverse magnetic field. The nuclear-electronic states are addressed via a magnetic resonance in the GHz frequency range usi ...

2016

A SIRT7-Dependent Acetylation Switch of GABPβ1 Controls Mitochondrial Function

Johan Auwerx, Kristina Schoonjans, Alessia Perino, Dongryeol Ryu, Hongbo Zhang, Matthias Alexander Sokrates Stein, Giuseppe Lo Sasso

Mitochondrial activity is controlled by proteins encoded by both nuclear and mitochondrial DNA. Here, we identify Sirt7 as a crucial regulator of mitochondrial homeostasis. Sirt7 deficiency in mice induces multisystemic mitochondrial dysfunction, which is ...

Cell Press2014

How adeno-associated virus Rep78 relocalises Cdc25B to arrest the cell cycle : the multiple interactions of Rep78 with cellular regulatory, replication and recombination proteins

Florence Magnin

Adeno-associated virus (AAV) is a small DNA virus belonging to the family of the parvoviridae. AAV infects the human population, however no disease has been associated with this virus. On the contrary, AAV was reported to have oncosuppressive activities. T ...

EPFL2009

Management of actinide waste inventories in nuclear phase-out scenarios

Rakesh Chawla, Marco Cometto

The improvement of the "radiological cleanliness" of nuclear energy is a primary goal in the development of advanced reactors and fuel cycles. The multiple recycling of actinides in advanced nuclear systems with fast neutron spectra represents a key option ...

Elsevier Ltd2008

Development and application of objective uncertainty measures for nuclear power plant transient analysis

Paolo Vinai

For the development, design and licensing of a nuclear power plant (NPP), a sound safety analysis is necessary to study the diverse physical phenomena involved in the system behaviour under a wide range of operational and transient conditions. Such studies ...

EPFL2007

Methodological Aspects of the Definition of a 2kW Society

Daniel Favrat, Pierre-André Haldi

The consumption of primary energy is often used to compare energy systems from a sustainability viewpoint at regional, national or even world level. For such comparisons to be “fair” and meaningful, this implies however to define primary energies in a cohe ...

2006