Publications associées à Heart sounds

Course Design - A Visual and Modular Approach

This book has been designed for instructors in higher education or adult training who wish to develop a new course or revise an existing one. It adopts a practical, visual, and modular approach based on the principle of constructive alignment. At its heart ...

EPFL Press2024

Hemodynamic effects of a dielectric elastomer augmented aorta on aortic wave intensity: An in-vivo study

Yves Perriard, Yoan René Cyrille Civet, Thomas Guillaume Martinez, Francesco Clavica, Armando Matthieu Walter, Silje Ekroll Jahren, Lorenzo Ferrari

Dielectric elastomer actuator augmented aorta (DEA) represents a novel approach with high potential for assisting a failing heart. The soft tubular device replaces a section of the aorta and increases its diameter when activated. The hemodynamic interactio ...

2023

DeepBreath-automated detection of respiratory pathology from lung auscultation in 572 pediatric outpatients across 5 countries

Martin Jaggi, Mary-Anne Hartley, Jonathan Dönz, Juliane Dervaux, Tatjana Chavdarova, Daniel Mueller, Julien Niklas Heitmann, Daniel Hinjos García

The interpretation of lung auscultation is highly subjective and relies on non-specific nomenclature. Computer-aided analysis has the potential to better standardize and automate evaluation. We used 35.9 hours of auscultation audio from 572 pediatric outpa ...

NATURE PORTFOLIO2023

Deep learning diagnostic and severity-stratification for interstitial lung diseases and chronic obstructive pulmonary disease in digital lung auscultations and ultrasonography: clinical protocol for an observational case-control study

Mary-Anne Hartley, Jonathan Dönz

BackgroundInterstitial lung diseases (ILD), such as idiopathic pulmonary fibrosis (IPF) and non-specific interstitial pneumonia (NSIP), and chronic obstructive pulmonary disease (COPD) are severe, progressive pulmonary disorders with a poor prognosis. Prom ...

BMC2023

A comprehensive mathematical model for cardiac perfusion

Alfio Quarteroni, Francesco Regazzoni, Christian Vergara

The aim of this paper is to introduce a new mathematical model that simulates myocardial blood perfusion that accounts for multiscale and multiphysics features. Our model incorporates cardiac electrophysiology, active and passive mechanics, hemodynamics, v ...

Nature Portfolio2023

Impact of atrial fibrillation on left atrium haemodynamics: A computational fluid dynamics study

Alfio Quarteroni, Luca Dede'

We analyse the haemodynamics of the left atrium, highlighting differences between healthy individuals and patients affected by atrial fibrillation. The computational study is based on patient-specific geometries of the left atria to simulate blood flow dyn ...

PERGAMON-ELSEVIER SCIENCE LTD2022

Computational methods for live heart imaging with speed-constrained microscopes

Olivia Mariani

Imaging methods to capture the beating and developing heart inside embryonic animal models such as the zebrafish are a key component for the study of fundamental biological processes such as cardiac birth defects or tissue regeneration. However, live heart ...

EPFL2021

Detection of myocardial medium‐chain fatty acid oxidation and tricarboxylic acid cycle activity with hyperpolarized [1– 13 C]octanoate

Arnaud Comment, Josefina Adriana Maria Bastiaansen, Hikari Ananda Infinity Yoshihara

Under normal conditions, the heart mainly relies on fatty acid oxidation to meet its energy needs. Changes in myocardial fuel preference are noted in the diseased and failing heart. The magnetic resonance signal enhancement provided by spin hyperpolarizati ...

2020

Marker-Free Automatic Quantification of Drug-Treated Cardiomyocytes with Digital Holographic Imaging

Gerardo Turcatti, Benjamin Rappaz, Fabien Kuttler, Bokyoung Kim, Pierre Marquet

We use quantitative phase digital holographic microscopy (QP-DHM) to image and quantify the beating movement of cardiomyocytes, derived from induced pluripotent stem cells (iPSCs), in control and drug-treated conditions. The development of an analysis algo ...

AMER CHEMICAL SOC2020

Increasing heart vascularisation after myocardial infarction using brain natriuretic peptide stimulation of endothelial and WT1(+) epicardial cells

Na Li, Alexia Laurie Carboni

Brain natriuretic peptide (BNP) treatment increases heart function and decreases heart dilation after myocardial infarction (MI). Here, we investigated whether part of the cardioprotective effect of BNP in infarcted hearts related to improved neovascularis ...

2020

Mapping Biological Current Densities With Ultrafast Acoustoelectric Imaging: Application to the Beating Rat Heart

Pierre-Marc Jean Marie Dansette

Ultrafast acoustoelectric imaging (UAI) is a novel method for the mapping of biological current densities, which may improve the diagnosis and monitoring of cardiac activation diseases such as arrhythmias. This paper evaluates the feasibility of performing ...

Institute of Electrical and Electronics Engineers2019

A 1D computer model of the arterial circulation in horses: An important resource for studying global interactions between heart and vessels under normal and pathological conditions

Nikolaos Stergiopoulos, Patrick Segers

Arterial rupture in horses has been observed during exercise, after phenylephrine administration or during parturition (uterine artery). In human pathophysiological research, the use of computer models for studying arterial hemodynamics and understanding n ...

2019

Synchrotron-based phase contrast imaging of cardiovascular tissue in mice-grating interferometry or phase propagation?

Nikolaos Stergiopoulos, Lydia Aslanidou, Bram Trachet, Goran Lovric, Mauro Ferraro, Patrick Segers

Synchrotron-based x-ray phase-contrast imaging allows for detailed 3D insight into the microstructure of soft tissue and is increasingly used to improve our understanding of mouse models of cardiovascular disease. Two techniques dominate the field: grating ...

2019

Relative Effects of the Hospital Readmissions Reduction Program on Hospitals That Serve Poorer Patients

Yun Wang, Christine Choirat

Importance: Hospitals that serve poorer populations have higher readmission rates. It is unknown whether these hospitals effectively lowered readmission rates in response to the Hospital Readmissions Reduction Program (HRRP). Objective: To compare pre-post ...

2019

Cylindrical Dielectric Elastomer Actuator for Cardiac Assist Device

Jonathan André Jean-Marie Chavanne

This work has been triggered because of the need for a new way to relieve the heart. Current solutions are based on invasive systems. The main problem of such assistance is infectious risks. State of the art to define an alternative has allowed highlightin ...

EPFL2019

Numerical approximation of cardiac electro-fluid-mechanical models : coupling strategies for large-scale simulation

Antonello Gerbi

The mathematical modeling of the heart involves several challenges, which are intrinsically related to the complexity of its function. A satisfactory cardiac model must be able to describe a wide range of different processes, such as the evolution of the t ...

EPFL2018

Noninvasive Stroke Volume Monitoring by Electrical Impedance Tomography

Fabian Braun

In clinical practice it is of vital importance to track the health of a patient's cardiovascular system via the continuous measurement of hemodynamic parameters. Cardiac output (CO) and the related stroke volume (SV) are two such parameters of central inte ...

EPFL2018

A matrix DEIM technique for model reduction of nonlinear parametrized problems in cardiac mechanics

Alfio Quarteroni, Andrea Manzoni

When relying on Newton iterations to solve nonlinear problems in the context of Reduced Basis (RB) methods, the assembling of the RB arrays during the online stage depends on the dimension of the underlying high-fidelity approximation. This is more of an i ...

Elsevier Science Sa2017

Identification of Abnormal Heart Sounds

Jean-Marc Vesin, Sasan Yazdani, Silas Schlatter, Seyyed Abbas Atyabi

As a part of 2016 Physionet/CinC callenge, this work aims at the detection of abnormal phonocardiogram (PCG) recordings. Heart sound signal analysis has been an active research topic over the past decades with various studies such as heart sound segmentati ...

2016

Methods for reliable estimation of pulse transit time and blood pressure variations using smartphone sensors

David Atienza Alonso, Francisco Javier Rincon Vallejos, Srinivasan Murali, Alair Dias Junior

Hypertension is known to affect around one third of adults globally and early diagnosis is essential to reduce the effects of this affliction. Today’s Blood Pressure (BP) monitoring cuffs are obtrusive and in- convenient for performing regular measurements ...

Elsevier Science Bv2016