Publications associées à Éthylènediamine

Shape and size control of colloidal CdSe nanocrystals in the presence of carboxylate and alkylamine ligands

In this thesis, we focus on investigating the shape and size evolution of colloidal CdSe nanomaterials in the presence of carboxylate and alkylamine surface ligands. By elaborating the combination of carboxylates and alkylamines with different hydrocarbon ...

EPFL2019

Chiral Cyclopentadienyls: Enabling Ligands for Asymmetric Rh(III)-Catalyzed C-H Functionalizations

Nicolai Cramer, Baihua Ye

Transition-metal catalyzed C-H functionalizations became a complementary and efficient bond-forming strategy over the past decade. In this respect, Cp*Rh(III) complexes have emerged as powerful catalysts for a broad spectrum of reactions giving access to s ...

American Chemical Society2015

Dinuclear DOTA-Based Gd-III Chelates - Revisiting a Straightforward Strategy for Relaxivity Improvement

Lothar Helm, Shima Karimi

The need for magnetic resonance imaging (MRI) contrast agents with improved relaxivity maintains the development of new Gd-III chelates as an intensive and demanding field of research. In this work, we introduce the new dimeric chelators bis{1,4,7,10-tetra ...

Wiley-Blackwell2015

Ligand substitutions between ruthenium-cymene compounds can control protein versus DNA targeting and anticancer activity

Paul Joseph Dyson, Ursula Röthlisberger, Wee Han Ang, Alexey Nazarov, Pablo Campomanes Ramos, Catherine Marie Amélie Clavel, Michael Groessl

Ruthenium compounds have become promising alternatives to platinum drugs by displaying specific activities against different cancers and favourable toxicity and clearance properties. Nonetheless, their molecular targeting and mechanism of action are poorly ...

Nature Research2014

Lanthanide Complexes Formed with the Tri- and Tetraacetate Derivatives of Bis(aminomethyl)phosphinic Acid: Equilibrium, Kinetic and NMR Spectroscopic Studies

André Merbach, Eva Jakab Toth, Laurent Quebatte

The lanthanide(III) complexes formed with the tri- and tetraacetate derivatives of bis(aminomethyl)phosphinic acid, L1 and L2, respectively, have been studied by pH potentiometry, spectrophotometry and 1H and 17O NMR spectroscopy. L1 forms [Ln(L1)], [Ln(L1 ...

Wiley-Blackwell2012

Synthesis and electronic properties of a pentafluoroethyl-derivatized nickel pincer complex

Xile Hu, Oleg Vechorkin, Peng Ren

The synthesis of a bis(amino)amide nickel pincer complex bearing a perfluoroethyl ligand was effected by reaction of the corresponding nickel chloride complex with cesium fluoride and trimethyl(pentafluoroethyl)silane. Electrochemical experiments revealed ...

Royal Society of Chemistry2012

A molecular probe for the optical detection of biogenic amines

Rosario Scopelliti, Kay Severin, Bo Ram Lee

A coumarin derivative was employed for the detection of biogenic amines in buffered aqueous solution by UV-Vis or fluorescence spectroscopy. Incorporated in a polymeric matrix, the dye can also be used for the optical detection of gaseous amines. ...

Royal Society of Chemistry2011

Anticancer activity of new organo-ruthenium, rhodium and iridium complexes containing the 2-(pyridine-2-yl)thiazole N,N-chelating ligand

Paul Joseph Dyson, Angela Casini, Fabio Edafe

The dinuclear dichloro complexes [(η6-arene)2Ru2(μ-Cl)2Cl2] and [(η5-C5Me5)2M2(μ-Cl)2Cl2] react with 2-(pyridine-2-yl)thiazole (pyTz) to afford the cationic complexes [(η6-arene)Ru(pyTz)Cl]+ (arene = C6H6 (1), p-iPrC6H4Me (2) or C6Me6 (3)) and [(η5-C5Me5)M ...

Elsevier2010

Binding of Organometallic Ruthenium(II) Anticancer Compounds to Nucleobases: A Computational Study

Ursula Röthlisberger, Ivano Tavernelli, Christian Gossens

The reaction of the anticancer compound (eta(6)-benzene)Ru(en)(OH2) (1) toward the nucleobases guanine, adenine, and cytosine is studied computationally using DFT/BP86 calculations. The aqua leaving group of such compounds is known to undergo ligand ...

2009

Homo- and Heterodinuclear Helicates of Lanthanide(III), Zinc(II) and Aluminium(III) Based on 8-Hydroxyquinoline Ligands

Jean-Claude Bünzli, Frédéric Gumy

Homonuclear helicates with rare-earth-metal(III) ions or heteronuclear derivatives with rare-earth-metal and aluminium or zinc centres are obtained in alkali-metal-templated selfassembly processes from isobutenylidene- bridged homoditopic bis(2-carb-Gamido ...

2009

In silico DNA-binding and rational design of ruthenium-arene anticancer drugs

Christian Gossens

Organometallic ruthenium(II)-arene (RA) antitumour compounds of the general type [Ru(II)(η6-arene)(X)2(pta)], RA-pta, and [Ru(II)(η6-arene)X(en)], RA-en, (X=leaving group; pta=1,3,5-triaza-7-phosphaadamantane, en=ethylenediamine) have been investigated com ...

EPFL2007

Mécanismes d'isomérisation et d'échange de ligand de complexes octaédriques labiles de cobalt (II) : étude par RMN et haute pression

Fabrice Riblet

There are only few structural thermodynamic and kinetic studies on labile octahedral complexes available today. Octahedral paramagnetic compounds of cobalt(II) have an optimum electronic relaxation leading to NMR spectra with good resolution. Therefore, th ...

EPFL2007

Toward the Rational Design of Lanthanide Coordination Polymers: a New Topological Approach

Jean-Claude Bünzli, Marinella Mazzanti

The implementation of four bidentate building blocks into a highdenticity linker with a flexible spacer leads to a predisposed ligand that allows one to direct the self- assembly of 1D functional coordination polymers. This is illustrated by the assembly u ...

2007

Biomimetic catalysis with immobilized transition metal complexes

Alexander Schiller

The tetradentate chelate ligand tris[(1-vinylimidazol-2-yl)methyl]amine (10) was synthesized in five steps from commercially available starting materials. Upon reaction with MCl2 (M = Zn, Cu, Ni, Co) in the presence of NH4PF6, the complexes [M(10)Cl]PF6 (M ...

EPFL2006

Heterobimetallic lanthanide helicates : deciphering substituent effects by crystallography and NMR analysis

Thomas Binderup Jensen

Based on the ligand LAB the new heterobitopic ligands LAB2, LAB3, LAB4 and LAB5 have been designed and synthesised. The five ligands were designed to selectively form heterobimetallic complexes of composition LnLn'(L)36 when reacted with a pair of ...

EPFL2006

The effect of pyridinecarboxylate chelating groups on the stability and electronic relaxation of gadolinium complexes

André Merbach, Lothar Helm, Marinella Mazzanti, Alain Borel

The ligand N,N'-bis[6-carboxy-2-pyridylmethyl]ethylenediamine-N,N'-diacetic acid (H4bpeda) was synthesized using an improved procedure which requires a reduced no. of steps and leads to a higher yield with respect to the published procedure. It was obtaine ...

2005

Highly cross-linked polymers containing N,N ',N ''-chelate ligands for the Cu(II)-mediated hydrolysis of phosphoesters

Rosario Scopelliti, Kay Severin, Alexander Schiller

Three immobilized Cu(II) complexes were generated by the following: (a) homopolymerization of the N,N',N '' chelate ligand tris[2-(1-vinylimidazolyl)]phosphine (1) and subsequent metalation with CuCl2; (b) copolymerization of 1 with ethyleneglycol dimethac ...

2005