Publications associées à Stress chez l'humain

Adolescent Stress-Induced Ventral Hippocampus Redox Dysregulation Underlies Behavioral Deficits and Excitatory/Inhibitory Imbalance Related to Schizophrenia

Maria del Carmen Sandi Perez, Dogukan Hazar Ülgen, Thamyris Silva

Background and hypothesis: Redox dysregulation has been proposed as a convergent point of childhood trauma and the emergence of psychiatric disorders, such as schizophrenia (SCZ). A critical region particularly vulnerable to environmental insults during ad ...

2024

Experimental and analytical investigation of shear-reinforced concrete and dowel action

Marko Pejatovic

Codes of practice can be overly conservative, particularly for the shear resistance of reinforced concrete beams with shear reinforcement when large loads act close to supports. This thesis addresses the topic by proposing a refined design approach based o ...

EPFL2024

Psychosomatic response to acute emotional stress in healthy students

Adriana Arza Valdes

The multidimensionality of the stress response has shown the complexity of this phenomenon and therefore the impossibility of finding a unique biomarker among the physiological variables related to stress. An experimental study was designed and performed t ...

FRONTIERS MEDIA SA2023

The effects of war on Ukrainian research

Gaétan Jean A de Rassenfosse, Wolf-Hendrik Peter Uhlbach, Tetiana Murovana

The ongoing war in Ukraine has profoundly impacted the Ukrainian scientific community. Numerous researchers have either emigrated or transitioned to alternate professions. For those who remain in research, the destruction of civil infrastructure and psycho ...

Springernature2023

Empathetic Conversational Agents for Distress Support

Kalpani Anuradha Welivita

Due to the increasing demands of today's fast-paced world, mental health concerns are on the rise, which necessitates innovative approaches to provide support to those in need. Open-domain conversational agents known as chatbots, offer a unique opportunit ...

EPFL2023

Single-Well Pore Pressure Preconditioning for Enhanced Geothermal System Stimulation

Marie Estelle Solange Violay, Mathias Alexandre David Lebihain, Barnaby Padraig Fryer

The stress state is an important parameter in terms of both earthquake nucleation and rupture. Here, a new stimulation technique is proposed for Enhanced Geothermal Systems (EGSs), which have previously been burdened with a number of high-profile incidence ...

2023

Fatigue behavior of transverse attachments under constant and variable amplitude loading from a Swiss motorway bridge

Alain Nussbaumer, Davide Leonetti, Yukina Takai

This paper investigates the fatigue behavior of non-load-carrying transverse welded steel attachments by reporting on an experimental characterization under constant and variable amplitude loading. Fatigue cracks have been monitored using DIC and ACPD tech ...

Elsevier Sci Ltd2023

Technology-Enabled Collaborative Care for Concurrent Diabetes and Distress Management During the COVID-19 Pandemic: Protocol for a Mixed Methods Feasibility Study

Sean Lewis Hill

Background: The COVID-19 pandemic disrupted the delivery of diabetes care and worsened mental health among many patients with type 2 diabetes (T2D). This disruption puts patients with T2D at risk for poor diabetes outcomes, especially those who experience ...

JMIR PUBLICATIONS, INC2023

Pore-pressure coefficients for unsaturated soils: generalized effective stress approach

Lyesse Laloui, Alessio Ferrari, Angelica Tuttolomondo

Geotechnical problems with total stress changes occurring rapidly relative to the soil consolidation time can be conveniently addressed using an effective stress-based approach. For saturated states, analytical formulations of pore-pressure coefficients ad ...

CANADIAN SCIENCE PUBLISHING2023

Linguistic effects on news headline success: Evidence from thousands of online field experiments (Registered Report)

Robert West, Kristina Gligoric

What makes written text appealing? In this registered report, we study the linguistic characteristics of news headline success using a large-scale dataset of field experiments (A/B tests) conducted on the popular website comparing multiple headline variant ...

PUBLIC LIBRARY SCIENCE2023

Monitoring On-Target Signaling Responses in Larval Zebrafish- Z-REX Unmasks Precise Mechanisms of Electrophilic Drugs and Metabolites

Yimon Aye, Jesse Poganik, Kuan-Ting Huang, Phillippe Ly

Reactive metabolites and related electrophilic drugs are among the most challenging small molecules to study. Conventional approaches to deconstruct the mode of action (MOA) of such molecules leverage bulk treatment of experimental specimens with an excess ...

JOURNAL OF VISUALIZED EXPERIMENTS2023

Quantitative study of the thickness-dependent stress in indium tin oxide thin films

Varun Gupta

A quantitative analysis of stress in indium tin oxide (ITO) films with varying thicknesses was conducted using high-precision stylus profilometry. The experimental results revealed a transition of the stress type from tensile to compressive as the ITO film ...

Elsevier Science Sa2023

'connEcted caesarean section': creating a virtual link between MOthers and their infanTs to ImprOve maternal childbirth experieNce - study protocol for a PILOT trial (e-motion-pilot)

Sandra Maria Marcadent, David Desseauve, Karine Lepigeon, Fiona Corbaz

IntroductionOne-third of mothers rate their childbirth as traumatic. The prevalence of childbirth-related post-traumatic stress disorder (CB-PTSD) is 4.7%. Skin-to-skin contact is a protective factor against CB-PTSD. However, during a caesarean section (CS ...

BMJ PUBLISHING GROUP2023

Crack tip kinematics reveal the process zone structure in brittle fracture

John Martin Kolinski, Chenzhuo Li, Xinyue Wei

When brittle hydrogels fail, several mechanisms conspire to alter the state of stress near the tip of a crack, and it is challenging to identify which mechanism is dominant. In the fracture of brittle solids, a sufficient far-field stress results in the co ...

PERGAMON-ELSEVIER SCIENCE LTD2023

Transcriptomic analysis reveals mitochondrial pathways associated with distinct adolescent behavioral phenotypes and stress response

Maria del Carmen Sandi Perez, Dogukan Hazar Ülgen, Thamyris Silva

Adolescent individuals exhibit great variability in cortical dynamics and behavioral outcomes. The developing adolescent brain is highly sensitive to social experiences and environmental insults, influencing how personality traits emerge. A distinct patter ...

2023

Opposite effects of stress on effortful motivation in high and low anxiety are mediated by CRHR1 in the VTA

Maria del Carmen Sandi Perez, Jocelin Grosse, Olivia Zanoletti, Simone Astori, Marie-Isabelle Guillot de Suduiraut, Ioannis Zalachoras, Mandy Meijer

Individuals frequently differ in their behavioral and cognitive responses to stress. However, whether motivation is differently affected by acute stress in different individuals remains to be established. By exploiting natural variation in trait anxiety in ...

2022

Negative Associations of Stress and Anxiety Levels With Cytotoxic and Regulatory Natural Killer Cell Frequency in Chronic Tinnitus

Patrick Karl Alois Neff

BackgroundDepression and anxiety are known to be associated with stress-induced changes in the immune system. Bothersome tinnitus can be related to stress and often co-occurs with depression and anxiety. This study investigates associations of psychologica ...

Frontiers Media2022

Persistence of variant selection in red gold alloys

Roland Logé, Cyril Cayron, Margaux Nathalie Dominique Larcher

Recently, a new thermally activated distortion with amplification (TADA) effect has been reported in red gold alloys caused by the A1 -> L1(0) phase transformation. The macroscopic amplification is due to the persistence of variant selection nucleated unde ...

ELSEVIER SCIENCE SA2022

Role of Stress History on the Swelling-Shrinkage Behavior of Compacted Scaly Clay

Alessio Ferrari

Compacted scaly clays are complex geomaterials widely used for the realization of dam cores and waste dump liners. This research aims to investigate the swelling/shrinkage behavior of these geomaterials subjected in an oedometric cell to complex hydromecha ...

ASCE-AMER SOC CIVIL ENGINEERS2022

Design of slender and squat reinforced concrete members with shear reinforcement

Aurelio Muttoni, Miguel Fernández Ruiz, Marko Pejatovic

As proposed in several design standards for structural concrete, including Eurocode 2 (EN:1992-1-1:2004) and fib's Model Code 2010, the shear design of slender members with shear reinforcement can be performed by means of consistent models based on suitabl ...

ERNST & SOHN2022