Publications associées à Angor de Prinzmetal

Implementation of an epicardial implantable MEMS sensor for continuous and real-time postoperative assessment of left ventricular activity in adult minipigs over a short- and long-term period

The sensing of left ventricular (LV) activity is fundamental in the diagnosis and monitoring of cardiovascular health in high-risk patients after cardiac surgery to achieve better short- and long-term outcome. Conventional approaches rely on noninvasive me ...

Aip Publishing2024

Interrelation between cardiac and brain small-vessel disease: a pilot quantitative PET and MRI study

Bénédicte Marie Maréchal, Ricardo Alberto Corredor Jerez

Background: Small-vessel disease (SVD) plays a crucial role in cardiac and brain ischemia, but little is known about potential interrelation between both. We retrospectively evaluated 370 patients, aiming at assessing the interrelation between cardiac and ...

Springernature2023

A comprehensive mathematical model for cardiac perfusion

Alfio Quarteroni, Francesco Regazzoni, Christian Vergara

The aim of this paper is to introduce a new mathematical model that simulates myocardial blood perfusion that accounts for multiscale and multiphysics features. Our model incorporates cardiac electrophysiology, active and passive mechanics, hemodynamics, v ...

Nature Portfolio2023

Polygenic Risk Scores for Prediction of Subclinical Coronary Artery Disease in Persons Living With HIV: The Swiss HIV Cohort Study

Jacques Fellay, Christian Axel Wandall Thorball

Background. In people living with human immunodeficiency virus (HIV) (PLWH), individual polygenic risk scores (PRSs) are associated with coronary artery disease (CAD) events. Whether PRSs are associated with subclinical CAD is unknown. ...

OXFORD UNIV PRESS INC2022

Association of Heart Rate Variability With Silent Brain Infarcts in Patients With Atrial Fibrillation

Jean-Marc Vesin, Vincent Schlageter

Purpose: Silent brain infarcts (SBI) are frequently detected in patients with atrial fibrillation (AF), but it is unknown whether SBI are linked to autonomic dysfunction. We aimed to explore the association of autonomic dysfunction with SBI in AF patients. ...

FRONTIERS MEDIA SA2021

Predicting future myocardial infarction from angiographies with deep learning

Pascal Frossard, Emmanuel Abbé, Ortal Yona Senouf, Olivier Muller, Ntorina Thanou, Thabodhan Mahendiran, Omar Raita, Stéphane Fournier, David Meier, Nicolas Dayer, Farhang Aminfar

In patients with stable Coronary Artery Disease (CAD), the identification of lesions which will be responsible of a myocardial infarction (MI) during follow-up remains a daily challenge. In this work, we propose to predict culprit stenosis by applying a de ...

2021

Heart Rate Variability Triangular Index as a Predictor of Cardiovascular Mortality in Patients With Atrial Fibrillation

Jean-Marc Vesin, Vincent Schlageter

Background Impaired heart rate variability (HRV) is associated with increased mortality in sinus rhythm. However, HRV has not been systematically assessed in patients with atrial fibrillation (AF). We hypothesized that parameters of HRV may be predictive o ...

2020

Novel Low Complexity Biomedical Signal Processing Techniques for Online Applications

Sasan Yazdani

Biomedical signal processing has become a very active domain of research nowadays. With the advent of portable monitoring devices, from accelerometer-enabled bracelets and smart-phones to more advanced vital sign tracking body area networks, this field has ...

EPFL2018

A Novel Short-term Event Extraction Algorithm for Biomedical Signals

Jean-Marc Vesin, Sasan Yazdani, Sibylle Fallet

In this paper we propose a fast novel non-linear filtering method named Relative-Energy (Rel-En), for robust short-term event extraction from biomedical signals. We developed an algorithm that extracts short- and long-term energies in a signal and provides ...

2018

Photodynamic therapy for the treatment of atherosclerotic plaque: Lost in translation?

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Manish Jain

Acute coronary syndrome is a life-threatening condition of utmost clinical importance, which, despite recent progress in the field, is still associated with high morbidity and mortality. Acute coronary syndrome results from a rupture or erosion of vulnerab ...

Wiley2017

Hierarchical Cardiac-Rhythm Classification Based on Electrocardiogram Morphology

David Atienza Alonso, Amir Aminifar, Elisabetta De Giovanni, Dionisije Sopic

Atrial Fibrillation (AF) is a type of cardiac arrhythmia that significantly increases the risk of stroke and heart failure. In general, in the case of patients affected by AF, their electrocardiogram (ECG) shows a typical pattern of irregular RR intervals ...

2017

Anti-apoA-1 auto-antibodies increase mouse atherosclerotic plaque vulnerability, myocardial necrosis and mortality triggering TLR2 and TLR4

Nikolaos Stergiopoulos

Auto-antibodies to apolipoprotein A-1 (anti-apoA-1 IgG) were shown to promote inflammation and atherogenesis, possibly through innate immune receptors signalling. Here, we aimed at investigating the role of Toll-like receptors (TLR) 2 and 4 on anti-apoA-1 ...

Schattauer Gmbh-Verlag Medizin Naturwissenschaften2015

Insights into the antiatherogenic molecular mechanisms of andrographolide against Porphyromonas gingivalis-induced atherosclerosis in rabbits

Amer Ashrafi

Atherosclerosis is the commonest and most important vascular disease. Andrographolide (AND) is the main bioactive component of the medicinal plant Andrographis paniculata and is used in traditional medicine. This study was aimed to evaluate the antiatherog ...

Springer2014

Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice

Melody Swartz

Reverse cholesterol transport (RCT) refers to the mobilization of cholesterol on HDL particles (HDL-C) from extravascular tissues to plasma, ultimately for fecal excretion. Little is known about how HDL-C leaves peripheral tissues to reach plasma. We first ...

American Society for Clinical Investigation2013

Increase of arginase activity in old apolipoprotein-E deficient mice under Western diet associated with changes in neurovascular unit

Rafaela Fernandes Da Silva, Jean-Christophe Copin

Aging and atherosclerosis are well-recognized risk factors for cardiac and neurovascular diseases. The Apolipoprotein E deficient (ApoE-/-) mouse on a high-fat diet is a classical model of atherosclerosis, characterized by the presence of atherosclerotic p ...

Biomed Central Ltd2012

Measures of spatiotemporal organization differentiate persistent from long-standing atrial fibrillation

Jean-Marc Vesin, Yann Prudat, Laurent Renaud Uldry, Jérôme Sébastien Van Zaen, Lukas Kappenberger

This study presents an automatic diagnostic method for the discrimination between persistent and long-standing atrial fibrillation (AF) based on the surface electrocardiogram (ECG). Standard 12-lead ECG recordings were acquired in 53 patients with either p ...

Oxford Univ Press2012

Early temporal and spatial regularization of persistent atrial fibrillation predicts termination and arrhythmia-free outcome

Laurent Renaud Uldry

BACKGROUND Termination of persistent atrial fibrillation (AF) is a valuable ablation endpoint but is difficult to anticipate. We evaluated whether temporal and spatial indices of AF regularization predict intraprocedural AF termination and outcome. ...

2011

Full Spectral Analysis of the Atrial Components in the ECG during Atrial Fibrillation

Lukas Kappenberger, Mathieu Lemay

Clinical standard 12-lead ECG recordings over 5 minutes on patients in atrial fibrillation or in atrial flutter were analyzed. After suppression of the signal components related to ventricular activity, the amplitude spectra of all leads were inspected. Th ...

IEEE2008

The role of actively released fibrin-conjugated VEGF for VEGF receptor 2 gene activation and the enhancement of angiogenesis

Jeffrey Alan Hubbell, Martin Ehrbar

A major challenge for therapeutic delivery of angiogenic agents such as vascular endothelial growth factor (VEGF) is to achieve sustained, low dose signaling leading to durable neovessel formation. To this end, we recently created a variant of VEGF(121), T ...

2008

Rehabilitation of St-Marc dam: Model studies for the spillways

Marcelo Leite Ribeiro, Sameh Ahmad Kantoush

The Saint-Marc dam, owned by EDF-France is a concrete gravity dam built between 1926 and 1930. It is located near Limoges (France) on the Taurion River and has currently two gated spillways, one 7.50 m wide on the right bank and the other with two passes o ...

2007