The prediction of implant behaviors in vivo by the use of easy-to-perform in vitro methods is of great interest in biomaterials research. In the field of bone implants, it is commonly accepted that a spontaneous formation of a hydroxyapatite (HA) layer on ...
Biocompatibility is one of the biggest challenges for biomaterials development. This issue arises in the case of coatings. Calcium phosphate (CP) coatings are currently used to cover femoral stem implants, while calcium titanate (CT) has also been proposed ...
The heterogeneous precipitation of calcium phosphates on calcium hydroxyapariLe (Ca-10(PO4)(4)OH)(2) or HAP) in the presence arid absence of fluoride is important in the formation of bone and teeth, protection against tooth decay, dental and skeletal fluor ...
An obvious means to improve the fixation of a cancellous bone screw is to augment the surrounding bone with cement. Previous studies have shown that bone augmentation with Calcium Phosphate (CaP) cement significantly improves screw fixation. Nevertheless, ...
The composition and evolution of a brushite-type calcium phosphate cement was investigated by Solid-State NMR and X-ray during the setting process. The cement is obtained by mixing beta-tricalcium phosphate [Ca-3(PO4)(2), beta-TCP] and monocalcium phosphat ...
Phosphate glass (PG) of the composition 0.46(CaO)–0.04(Na2O)–0.5(P2O5) was used as filler in poly-L-lactic acid (PLA) foams developed as degradable scaffolds for bone tissue engineering. The effect of PG on PLA was assessed both in bulk and porous composit ...
Only with appropriate coatings and coating techniques the use of nanoparticles is possible for biomedical applications. The appropriate choice of the coating material and techniques helps to render the particles biocompatible, colloidally and chemically st ...
The gene therapy approach presented in this protocol employs a polymer encapsulated, xenogenic, transfected cell line to release human ciliary neurotrophic factor (hCNTF) for the treatment of Amyotrophic Lateral Sclerosis (ALS). A tethered device, containi ...
