Publications associées à Left-brain interpreter

Molecular reconstruction and simulation of the Neuron-Glia-Vasculature system

The outstanding information processing capacity of the brain relies on numerous molecular mechanisms. It is an extremely energy-expensive function, which involves specialization and collaboration of different cell types. A common framework to study the com ...

EPFL2023

Common and distinct brain networks of autoscopic phenomena

Olaf Blanke, Lukas Heydrich, Eva Blondiaux

Objective Autoscopic phenomena (AP) are illusory own body reduplications characterized by the visual perception of a second own body in extrapersonal space, and include three main forms: autoscopic hallucination (AH), heautoscopy (HAS) and out-of-body-expe ...

2021

Fronto-Temporal Disconnection Within the Presence Hallucination Network in Psychotic Patients With Passivity Experiences

Olaf Blanke, Alessandra Griffa, Jevita Potheegadoo, Kim Do, Patric Hagmann, Nathan Quentin Faivre, Roy Salomon, Giulio Rognini, Eva Blondiaux, Giedre Stripeikyte, Pierre Progin

Psychosis, characterized by hallucinations and delusions, is a common feature of psychiatric disease, especially schizophrenia. One prominent theory posits that psychosis is driven by abnormal sensorimotor predictions leading to the misattribution of self- ...

2021

Synchronous nonmonotonic changes in functional connectivity and white matter integrity in a rat model of sporadic Alzheimer's disease

Bernard Lanz, Katarzyna Pierzchala, Ileana Ozana Jelescu, Carole Poitry-Yamate, Ting Yin, Yujian Diao

Brain glucose hypometabolism has been singled out as an important contributor and possibly main trigger to Alzheimer's disease (AD). Intracerebroventricular injections of streptozotocin (icv-STZ) cause brain glucose hypometabolism without systemic diabetes ...

2020

Understanding Computational Costs of Cellular-Level Brain Tissue Simulations Through Analytical Performance Models

Felix Schürmann, Francesco Cremonesi

Computational modeling and simulation have become essential tools in the quest to better understand the brain's makeup and to decipher the causal interrelations of its components. The breadth of biochemical and biophysical processes and structures in the b ...

HUMANA PRESS INC2020

Temporal Dissociation of Neocortical and Hippocampal Contributions to Mental Time Travel Using Intracranial Recordings in Humans

Olaf Blanke

In mental time travel (MTT) one is "traveling" back-and-forth in time, remembering, and imagining events. Despite intensive research regarding memory processes in the hippocampus, it was only recently shown that the hippocampus plays an essential role in e ...

2018

Inter-hemispherical asymmetry in default-mode functional connectivity and BAIAP2 gene are associated with anger expression in ADHD adults

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti, Djalel Eddine Meskaldji

Attention deficit hyperactivity disorder (ADHD) is accompanied by resting-state alterations, including abnormal activity, connectivity and asymmetry of the default-mode network (DMN). Concurrently, recent studies suggested a link between ADHD and the prese ...

Elsevier2017

Cortico-reticulo-spinal circuits mediate functional recovery after spinal cord contusion

Léonie Asboth

After a spinal cord injury (SCI), only half of affected individuals regain voluntary control of leg movements below the level of the lesion. Anatomical, electrophysiological and imaging data revealed that even the most severe forms of SCI usually spare a s ...

EPFL2017

Common and distinct brain regions processing multisensory bodily signals for peripersonal space and body ownership

Olaf Blanke, Andrea Serino, Petr Grivaz

We take the feeling that our body belongs to us for granted. However, recent research has shown that it is possible to alter the subjective sensation of body ownership (BO) by manipulating multisensory bodily inputs. Several frontal and parietal regions ar ...

Elsevier2017

Decreased integration and information capacity in stroke measured by whole brain models of resting state activity

Alessandra Griffa, Patric Hagmann

While several studies have shown that focal lesions affect the communication between structurally normal regions of the brain, and that these changes may correlate with behavioural deficits, their impact on brain's information processing capacity is curren ...

Oxford Univ Press2017

The Insula Mediates Access to Awareness of Visual Stimuli Presented Synchronously to the Heartbeat

Olaf Blanke, Bruno Herbelin, Jonathan Dönz, Roy Salomon, Roberta Ronchi, Nathan Quentin Faivre, Javier Bello Ruiz, Rémi Martet

The processing of interoceptive signals in the insular cortex is thought to underlie self-awareness. However, the influence of interoception on visual awareness and the role of the insular cortex in this process remain unclear. Here, we show in a series of ...

Soc Neuroscience2016

Representation of Sound Objects within Early-Stage Auditory Areas: A Repetition Effect Study Using 7T fMRI

Wietske Van der Zwaag, Melissa Saenz, Stephanie Clarke

Environmental sounds are highly complex stimuli whose recognition depends on the interaction of top-down and bottom-up processes in the brain. Their semantic representations were shown to yield repetition suppression effects, i. e. a decrease in activity d ...

Public Library of Science2015

Motor Control in the Mouse Whisker System

Varun Sreenivasan

The motor systems of the mammalian brain are a remarkable product of many millions of years of evolution. It is the motor systems that make us and other mammals mobile, that guide our actions in response to sensory information and conversely modulate the v ...

EPFL2015

Anatomical Priors to improve Global Tractography

Jean-Philippe Thiran, Alessandro Daducci, Alia Lemkaddem

The main assumption of fiber-tracking algorithms is that fiber trajectories are represented by paths of highest diffusion, which is usually accomplished by following the principal diffusion directions in every voxel. The state-of-the-art approaches known a ...

2014

Global tractography with embedded anatomical priors for quantitative connectivity analysis

Jean-Philippe Thiran, Alessandro Daducci, Alia Lemkaddem, Didrik Hans Malcolm Skiöldebrand

Tractography algorithms provide us with the ability to non-invasively reconstruct fiber pathways in the white matter (WM) by exploiting the directional information described with diffusion magnetic resonance. These methods could be divided into two major c ...

2014

Computational Neuroscience Breakthroughs Through Innovative Data Management

Anastasia Ailamaki, Thomas Heinis, Farhan Tauheed, Sadegh Heyrani Nobari, Laurynas Biveinis

Simulations have become key in many scientific disciplines to better understand natural phenomena. Neuroscientists, for example, build and simulate increasingly fine grained models (including subcellular details, e.g., neurotransmitter) of the neocortex to ...

2013

Distinct illusory own-body perceptions caused by damage to posterior insula and extrastriate cortex

Olaf Blanke, Lukas Heydrich

Recent research in cognitive neuroscience using virtual reality, robotic technology and brain imaging has linked self-consciousness to the processing and integration of multisensory bodily signals. This work on bodily self-consciousness has implicated the ...

2013

Virtual reality based Brain-Machine-Interface for Sensori-Motor and Social experiments with Primates

Solaiman Shokur

As a result of improved understanding of brain mechanisms as well as unprecedented technical advancement in neural recording methods and computer technology, it is now possible to translate large-scale brain signals into movement intentions in real time. S ...

EPFL2013

Characterisation of Living Matter Using Advanced Spectroscopy Techniques

Markus Bonda

In the context of an ageing society neurodegenerative disease have become more and more frequent among humans. Opposing the benefits of a longer life, these diseases have thus triggered research on neurons and how they interact with each other. In vitro as ...

EPFL2011

Synchrotron Infrared Microspectroscopy Detecting the Evolution of Huntington's Disease Neuropathology and Suggesting Unique Correlates of Dysfunction in White versus Gray Brain Matter

László Forró, Sylvia Jeney, Heike Runne, Markus Bonda

Huntington's disease (HD), caused by a mutation of the corresponding gene encoding the protein huntingtin (htt), is characterized by progressive deterioration of cognitive and motor functions, paralleled by extensive loss of striatal neurons. At the cellul ...

2011