Publications associées à Vestibular membrane

Variants in USP48 encoding ubiquitin hydrolase are associated with autosomal dominant non-syndromic hereditary hearing loss

Non-Syndromic Hereditary Hearing Loss (NSHHL) is a genetically heterogeneous sensory disorder with about 120 genes already associated. Through exome sequencing (ES) and data aggregation, we identified a family with six affected individuals and one unrelate ...

Oxford University Press2021

Circadian Regulation of Cochlear Sensitivity to Noise by Circulating Glucocorticoids

Frédéric Bruno Martin Gachon, Benjamin Dieter Weger

The cochlea possesses a robust circadian clock machinery that regulates auditory function. How the cochlear clock is influenced by the circadian system remains unknown. Here, we show that cochlear rhythms are system driven and require local Bmal1 as well a ...

2019

The Changing Paradigm for the Surgical Treatment of Large Vestibular Schwannomas

Constantin Tuleasca

Objective Planned subtotal resection followed by Gamma Knife surgery (GKS) in patients with large vestibular schwannoma (VS) has emerged during the past decade, with the aim of a better functional outcome for facial and cochlear function. Methods We prospe ...

2018

Modulation of vection latencies in the full-body illusion

Olaf Blanke, Bruno Herbelin, Alessandro Nesti, Giulio Rognini

Current neuroscientific models of bodily self-consciousness (BSC) argue that inaccurate integration of sensory signals leads to altered states of BSC. Indeed, using virtual reality technology, observers viewing a fake or virtual body while being exposed to ...

2018

Optical proximity sensing system for atraumatic cochea implant surgery

Demetri Psaltis, Ye Pu, Christophe Moser, Ye Pu

The design of a proximity sensor to be integrated into cochlea implants is described. The sensor allows the anticipation of contact between the cochlear implant and intracochlear structures, including the cochlear canal wall and basilar membrane, providing ...

2017

Balancing the Self

Mariia Kaliuzhna

The vestibular system is composed of otolith organs and semi-circular canals that encode linear and angular accelerations, as well as the position of the head with respect to gravity. Thus, the detection of self-motion, the distinction between self- and ob ...

EPFL2015

Vestibular contribution to bodily self-consciousness and multisensory cortical processing

Christian Pfeiffer

How does the self relate to the body? Bodily self-consciousness, i.e. the sense of being a subject bound to a body, involves a first-person perspective (1PP), i.e. the sense of being directed at the world. Prior research suggests that bodily self-conscious ...

EPFL2015

Vestibular Processing and its Cortical Signature in Humans

Steven Gale

The vestibular system encodes rotations and translations of the head in space. While much is known about cortical processing of the classical Aristotelian sensory modalities, such as vision and touch, knowledge of how vestibular stimulation is encoded in t ...

EPFL2015

Oscillatory neural responses evoked by natural vestibular stimuli in humans

Olaf Blanke, Bruno Herbelin, Christophe Lopez, Aaron Schurger, Steven Gale

While there have been numerous studies of the vestibular system in mammals, less is known about the brain mechanisms of vestibular processing in humans. In particular, of the studies that have been carried out in humans over the last 30 years, none has inv ...

American Physiological Society2015

Multisensory Spatial Mechanisms of the Bodily Self and Social Cognition - A Commentary on Vittorio Gallese and Valentina Cuccio

Christian Pfeiffer

This commentary aims to find the right description of the pre-reflective brain mechanisms underlying our phenomenal experience of being a subject bound to a physical body (bodily self) and basic cognitive, perceptual, and subjective aspects related to inte ...

2015

Nobel Prize centenary: Robert Barany and the vestibular system

Olaf Blanke, Christophe Lopez

The hundredth anniversary of Robert Barany's Nobel Prize in Medicine offers the opportunity to highlight the importance of his discoveries on the physiology and pathophysiology of the vestibular organs. Barany developed the method of caloric vestibular sti ...

Cell Press2014

Vestibular-Somatosensory Interactions: Effects of Passive Whole-Body Rotation on Somatosensory Detection

Olaf Blanke, Bruno Herbelin, Mariia Kaliuzhna

Vestibular signals are strongly integrated with information from several other sensory modalities. For example, vestibular stimulation was reported to improve tactile detection. However, this improvement could reflect either a multimodal interaction or an ...

Public Library of Science2014

The vestibular system: a spatial reference for bodily self-consciousness

Olaf Blanke, Andrea Serino, Christian Pfeiffer

Self-consciousness is the remarkable human experience of being a subject: the “I”. Self- consciousness is typically bound to a body, and particularly to the spatial dimensions of the body, as well as to its location and displacement in the gravitational fi ...

Frontiers Research Foundation2014

Precise toxigenic ablation of intermediate cells abolishes the "battery" of the cochlear duct

Friedrich Beermann

The extracellular potential of excitable and nonexcitable cells with respect to ground is ∼0 mV. One of the known exceptions in mammals is the cochlear duct, where the potential is ∼80-100 mV, called the endocochlear potential (EP). The EP serves as the "b ...

Society for Neuroscience2013

The thalamocortical vestibular system in animals and humans

Olaf Blanke, Christophe Lopez

The vestibular system provides the brain with sensory signals about three-dimensional head rotations and translations. These signals are important for postural and oculomotor control, as well as for spatial and bodily perception and cognition, and they are ...

Elsevier2011

Functional and neural mechanisms of embodiment: importance of the vestibular system and the temporal parietal junction

Olaf Blanke, Bigna Lenggenhager

Embodiment, the sense of being localized within one's physical body, is a fundamental aspect of the self. Recent research shows that self and body processing as well as embodiment require distinct brain mechanisms. Here, we review recent clinical and neuro ...

Freund Publishing House2006