Publications associées à Chambre antérieure de l'œil

Intraocular Lens Refractive Index and Its Impact on External Surface Reflections

PURPOSE: To determine and compare the origin of the external surface reflections produced by commonly used intraocular lenses (IOLs). ...

SLACK INC2021

Outcome and Complications of Combined Modified Deep Sclerectomy and Trabeculectomy for Surgical Management of Glaucoma: A Pilot Study

André Mermoud, Sylvain Roy

Purpose: To report the outcome and complications of a combined surgical technique of modified deep sclerectomy and trabeculectomy (mDST) for glaucoma. Patients and Methods: Retrospective study of 44 eyes of 43 patients with open and closed angle glaucoma w ...

2020

MRI after successful eyeWatch(TM) implantation

Nikolaos Stergiopoulos, André Mermoud, Sylvain Roy, Adan Villamarin

The eyeWatch(TM) is a new glaucoma drainage device that includes an adjustable mechanism that can vary the resistance to aqueous humor outflow during the postoperative period to reduce the burden of postoperative intraocular pressure (IOP) management. The ...

SAGE PUBLICATIONS LTD2020

EyeWatch Rescue of Refractory Hypotony After Baerveldt Drainage Device Implantation: Description of a New Technique

André Mermoud, Nikolaos Stergiopoulos, Adan Villamarin, Sina Elahi

The most effective way to control glaucoma is by lowering intraocular pressure (IOP) in order to prevent the progression of the disease. Glaucoma drainage devices (GDDs) are surgical option reserved for refractory cases and have been designed to address kn ...

LIPPINCOTT WILLIAMS & WILKINS2020

Initial Clinical Results of the eyeWatch: a New Adjustable Glaucoma Drainage Device Used in Refractory Glaucoma Surgery

Nikolaos Stergiopoulos, André Mermoud, Sylvain Roy, Adan Villamarin, Stéphane Bigler, Constantinos Stergiopulos

Precis: In this study, we report clinical results after implantation of an adjustable glaucoma drainage device. The intraocular pressure (IOP) profile was efficiently controlled postoperatively as the resistance to aqueous humor outflow was finely adjusted ...

LIPPINCOTT WILLIAMS & WILKINS2019

Ocular Structures Segmentation from Multi-sequences MRI Using 3D Unet with Fully Connected CRFs

Meritxell Bach Cuadra, Raphael Sznitman, Alessia Pica

The use of 3D Magnetic Resonance Imaging (MRI) has attracted growing attention for the purpose of diagnosis and treatment planning of intraocular ocular cancers. Precise segmentation of such tumors are highly important to characterize tumors, their progres ...

SPRINGER INTERNATIONAL PUBLISHING AG2018

Corneal epithelial stem cells and their niche at a glance

Freddy Radtke, Craig Nowell

The corneal epitheliumacts as a protective barrier on the anterior ocular surface and is essential for maintaining transparency of the cornea and thus visual acuity. During both homeostasis and repair, the corneal epithelium is maintained by self-renewing ...

Company Of Biologists Ltd2017

Eyewatch, an Innovative Adjustable GDD for the Treatment of Glaucoma - in Vivo Results

Nikolaos Stergiopoulos, André Mermoud, Sylvain Roy, Adan Villamarin, Stéphane Bigler

PURPOSE: To report the in vivo results of a continuously adjustable glaucoma drainage device (GDD) in glaucoma surgery with rabbits. METHODS: Under general anesthesia, the AGDD was implanted on 12 white New-Zealand rabbits for duration of 6 months. The adj ...

Springer2016

Longitudinal three-dimensional visualisation of autoimmune diabetes by functional optical coherence imaging

Theo Lasser, Martin Villiger, Anne Grapin-Botton, Arno Pino Bouwens, Corinne Berclaz, Daniel Pawel Szlag, Jérôme Extermann, Joan Goulley

Aims/hypothesis It is generally accepted that structural and functional quantitative imaging of individual islets would be beneficial to elucidate the pathogenesis of type 1 diabetes. We here introduce functional optical coherence imaging (FOCI) for fast, ...

Springer Verlag2016

Results of CO2 Laser-assisted Deep Sclerectomy as Compared With Conventional Deep Sclerectomy

André Mermoud, Sylvain Roy

Purpose: To evaluate the efficacy of CO2 laser-assisted sclerectomy surgery (CLASS) compared with classic nonpenetrating deep sclerectomy (NPDS) with implant in medically uncontrolled glaucoma patients. Materials and Methods: Patients who underwent primary ...

Lippincott, Williams & Wilkins2016

Molecular Analysis of NOTCH2 in Patients with Primary Open-Angle Glaucoma

Background and Purpose: Transgenic mice over-expressing Notch2 in the uvea exhibit a hyperplastic ciliary body leading to increased IOP and glaucoma. The aim of this study was to investigate the possible presence of NOTCH2 variants in patients with primary ...

Georg Thieme Verlag Kg2015

A New Adjustable Glaucoma Drainage Device

Nikolaos Stergiopoulos, Sylvain Roy, Adan Villamarin, Stéphane Bigler

PURPOSE. This work is focused on the testing of a new experimental noninvasively adjustable glaucoma drainage device (AGDD) that allows for the control of its outflow resistance to modulate intraocular pressure (IOP) in a customized fashion. METHODS. Six A ...

Association for Research in Vision and Ophthalmology2014

Notch Signaling in Pigment Cells and Generation of Mouse Models for Ocular Diseases

Bhushan Sarode

Cellular signaling mediated by Notch receptors results in coordinated regulation of cell growth, survival and differentiation. In melanocytes, Notch signaling is essential for the maintenance of melanocytes and the melanocyte stem cell population. Whereas, ...

EPFL2013

3D simulation of the aqueous flow in the human eye

Nikolaos Stergiopoulos, Sylvain Roy, Adan Villamarin, Philippe Reymond, Orestis Vardoulis, Reda Hasballa

Glaucoma results in an increase in the resistance of the aqueous humor outflow, which in turn leads to an increase of the intraocular pressure (IOP). Several treatments are proposed to reduce and stabilize the IOP that include medications, filtering surger ...

Elsevier Sci Ltd2012

Oligopotent stem cells are distributed throughout the mammalian ocular surface

Yann Barrandon, Ariane Rochat, Georges Abou Jaoudé

The integrity of the cornea, the most anterior part of the eye, is indispensable for vision. Forty- five million individuals worldwide are bilaterally blind and another 135 million have severely impaired vision in both eyes because of loss of corneal trans ...

2008

Time-domain optical coherence tomography with digital holographic microscopy

Christian Depeursinge, Etienne Cuche, Pierre Marquet, Florian Charrière, Pia Massatsch

We show that digital holography can be combined easily with optical coherence tomography approach. Varying the reference path length is the means used to acquire a series of holograms at different depths, providing after reconstruction images of slices at ...

2005

First steps toward noninvasive intraocular pressure monitoring with a sensing contact lens

Philippe Renaud, Arnaud Bertsch, Matteo Leonardi

PURPOSE. To present a novel and minimally invasive approach to intraocular pressure (IOP) monitoring based on a sensing contact lens. METHODS. The key element of this measurement method is a soft contact lens with an embedded microfabricated strain gauge a ...

2004

Low coherence digital holographic microscopy : applications to vision in turbid media and biomedical imaging

Pia Massatsch

A new holographic technique combining digital holographic microscopy with the use of low coherence light has been developed and the potential of the resulting method for vision in turbid media and biomedical imaging has been evaluated. In digital holograph ...

EPFL2003

Optische Augenlängenmessung für klinische Anwendungen

Beate Möller

Cataract is the leading cause of blindness worldwide. The clouding of the human eye lens is called "Grauer Star" in German. In the industrialized countries this process of increased blindness is corrected by the surgical removal of the clouded lens and its ...

EPFL2001