Publications associées à Tendon d'Achille

Micro- and nanostructure specific X-ray tomography reveals less matrix formation and altered collagen organization following re duce d loading during Achilles tendon healing

Recovery of the collagen structure following Achilles tendon rupture is poor, resulting in a high risk for re-ruptures. The loading environment during healing affects the mechanical properties of the tendon, but the relation between loading regime and heal ...

Elsevier Sci Ltd2023

Vertical and Leg Stiffness Modeling During Running: Effect of Speed and Incline

Kamiar Aminian, Frédéric Meyer, Mathieu Pascal Falbriard, Grégoire Millet

A spring mass model is often used to describe human running, allowing to understand the concept of elastic energy storage and restitution. The stiffness of the spring is a key parameter and different methods have been developed to estimate both the vertica ...

GEORG THIEME VERLAG KG2023

Investigating the neuromechanical control of healthy gait modulation and pathological gaits observed in cerebral palsy using neuromuscular simulations

Andrea Di Russo

Locomotion is based on a sophisticated interaction among the environment, the musculoskeletal system, the spinal cord, and the brain locomotor areas. Quality of life is strongly related to the proper capability of this movement. However, many pathologies, ...

EPFL2023

Novel Design and Implementation of a Neuromuscular Controller on a Hip Exoskeleton for Partial Gait Assistance

Auke Ijspeert, Mohamed Bouri, Ali Reza Manzoori, Andrea Di Russo, Sara Messara

Exoskeletons intended for partial assistance of walking should be able to follow the gait pattern of their users, via online adaptive control strategies rather than imposing predefined kinetic or kinematic profiles. NeuroMuscular Controllers (NMCs) are ada ...

2023

Aging and matrix viscoelasticity affect multiscale tendon properties and tendon derived cell behavior

Yann Tinguely

Aging is the largest risk factor for Achilles tendon associated disorders and rupture. Although Achilles tendon macroscale elastic properties are suggested to decline with aging, less is known about the effect of maturity and aging on multiscale viscoelast ...

ELSEVIER SCI LTD2022

Neuromuscular Controller Embedded in a Powered Ankle Exoskeleton: Effects on Gait, Clinical Features and Subjective Perspective of Incomplete Spinal Cord Injured Subjects

Auke Ijspeert, Florin Dzeladini

Powered exoskeletons are among the emerging technologies claiming to assist functional ambulation. The potential to adapt robotic assistance based on specific motor abilities of incomplete spinal cord injury (iSCI) subjects, is crucial to optimize Human-Ro ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2020

Modeling knee osteoarthritis pathophysiology using an integrated joint system (IJS): a systematic review of relationships among cartilage thickness, gait mechanics, and subchondral bone mineral density

Julien Favre, Brigitte Jolles-Haeberli

Objective: To introduce an integrated joint system (IJS) model of joint health and osteoarthritis (OA) pathophysiology through a systematic review of the cross-sectional relationships among three knee properties (cartilage thickness, gait mechanics, and su ...

ELSEVIER SCI LTD2018

Answer validation for generic crowdsourcing tasks with minimal efforts

Karl Aberer

Crowdsourcing has been established as an essential means to scale human computation in diverse Web applications, reaching from data integration to information retrieval. Yet, crowd workers have wide-ranging levels of expertise. Large worker populations are ...

2017

Alignment of collagen fiber in knitted silk scaffold for functional massive rotator cuff repair

Dominique Pioletti, Weiliang Shen, Ting Zhu, Jiayun Huang

Rotator cuff tear is one of the most common types of shoulder injuries, often resulting in pain and physical debilitation. Allogeneic tendon-derived decellularized matrices do not have appropriate pore size and porosity to facilitate cell infiltration, whi ...

Elsevier2017

Effects of a neuromuscular controller on a powered ankle exoskeleton during human walking

Auke Ijspeert, Arash Arami, Florin Dzeladini, Etienne Burdet, Amy Roning Wu, Daniel Renjewski

Wearable devices to assist abnormal gaits require controllers that interact with the user in an intuitive and unobtrusive manner. To design such a controller, we investigated a bio-inspired walking controller for orthoses and prostheses. We present (i) a S ...

Ieee2016

MOVING ALONG In biomechanics, rehabilitation engineering, and movement analysis, Italian researchers are making great strides

Silvestro Micera

In Italy, biomechanics research and the analysis of human and animal movement have had a very long history, beginning with the exceptional pioneering work of Leonardo da Vinci. In 1489, da Vinci began investigating human anatomy, including an examination o ...

Ieee-Inst Electrical Electronics Engineers Inc2015

Effect of Patient Specific Parameters on Degenerative Shoulder Diseases

Christoph Anselm Engelhardt

Osteoarthritis and rotator cuff tears are two common and wide spread shoulder diseases leading to significant restrictions in the daily life of the affected. The pathogenesis is not fully understood yet. A chronic process triggered by multiple causes is as ...

EPFL2015

Device for a Novel Hand and Wrist Rehabilitation Strategy for Stroke Patients Based on Illusory Movements Induced by Tendon Vibration

Mike Domenik Rinderknecht

This paper presents a new device for a novel neurorehabilitation strategy for stroke patients suffering from upper limb paralysis. The concept consists in combining illusory movements, induced by tendon vibration on the hand and wrist, with a virtual reali ...

Ieee2012

Imidazoacridinone-dependent lysosomal photodestruction: a pharmacological Trojan horse approach to eradicate multidrug-resistant cancers

Hubert van den Bergh, Patrycja Nowak-Sliwinska

Multidrug resistance (MDR) remains a primary hindrance to curative cancer therapy. Thus, introduction of novel strategies to overcome MDR is of paramount therapeutic significance. Sequestration of chemotherapeutics in lysosomes is an established mechanism ...

2012

Comparing localized and nonlocalized dynamic 31P magnetic resonance spectroscopy in exercising muscle at 7T

Christine Nabuurs

By improving spatial and anatomical specificity, localized spectroscopy can enhance the power and accuracy of the quantitative analysis of cellular metabolism and bioenergetics. Localized and nonlocalized dynamic 31P magnetic resonance spectroscopy using a ...

Wiley-Blackwell2012

Phosphocreatine line with changes in localised 31P MRS of exercising muscle at 7T

Rolf Gruetter, Christine Nabuurs

The aim was to investigate changes in the line width of high-energy phosphates solely originating from the intramyocellular compartment by temporally resolved localised 31P-MRS after aerobic calf muscle exercise. Semi-Laser [2] localised 31P-MRS of gastroc ...

2011

Modeling perceptual learning: why mice do not play backgammon

Michael Herzog, Elisa Tartaglia, Carl Kristoffer Aberg

Perceptual learning is often considered one of the simplest and basic forms of learning in general. Accordingly, it is usually modeled with simple and basic neural networks which show good results in grasping the empirical data. Simple meets simple. Comple ...

2009

Epigenetic Deregulation of DNA Repair and Its Potential for Therapy

Epigenetic silencing of essential components of DNA repair pathways is a common event in many tumor types, and comprise O6-methylguanine-DNA methyltransferase (MGMT), human mut L homolog 1 (hMLH1), Werner syndrome gene (WRN), breast cancer susceptibility g ...

2009

Multimodal x-ray scatter imaging

We describe a small-angle x-ray scattering-based imaging technique that reveals the distribution and orientation of nano-scale structures over extended areas. By combining two measurement and analysis schemes, complementary structural information is availa ...

2009