Publications associées à Surpopulation

Identifying genetic and dietary modulators of metabolic disorders using systems genetics

Long-term consumption of lipid-rich foods can contribute to common metabolic diseases and systemic low-grade inflammation. However, dietary responses and the development of non-communicable diseases are shaped by genetic factors and gene-by-environment int ...

EPFL2023

Impact of population size on early adaptation in rugged fitness landscapes

Anne-Florence Raphaëlle Bitbol, Richard Marie Servajean

Owing to stochastic fluctuations arising from finite population size, known as genetic drift, the ability of a population to explore a rugged fitness landscape depends on its size. In the weak mutation regime, while the mean steady-state fitness increases ...

ROYAL SOC2023

Hyperdimensional computing for biosignal monitoring: Applications for epilepsy detection

Una Pale

Hyperdimensional (HD) computing is a novel approach to machine learning inspired by neuroscience, which uses vectors in a hyper-dimensional space to represent data and models. This approach has gained significant interest in recent years with applications ...

EPFL2023

Experimental Study on Bedload Transport and Bedforms: Behaviour and Interplay in Steep Turbulent Streams

Ivan Pascal

In mountain regions, steep streams play an important role in water and sediment connectivity. In these highly dynamic systems, water flow features, sediment fluxes and stream morphologies are tightly interlinked over a broad range of temporal and spatial s ...

EPFL2022

A platform for experimental precision medicine: The extended BXD mouse family

Johan Auwerx, Evan Graehl Williams

The challenge of precision medicine is to model complex interactions among DNA variants, phenotypes, development, environments, and treatments. We address this challenge by expanding the BXD family of mice to 140 fully isogenic strains, creating a uniquely ...

CELL PRESS2021

A Machine-Generated View of the Role of Blood Glucose Levels in the Severity of COVID-19

Henry Markram, Emmanuelle Logette, Samuel Claude Kerrien, Enrico Scantamburlo, Daniel Keller, Jay Coggan, Cyrille Pierre Henri Favreau, Francesco Casalegno, Mohameth François Sy, Anna-Kristin Kaufmann, Pierre-Alexandre Fonta, Marine Laure Bertschy

SARS-CoV-2 started spreading toward the end of 2019 causing COVID-19, a disease that reached pandemic proportions among the human population within months. The reasons for the spectrum of differences in the severity of the disease across the population, an ...

FRONTIERS MEDIA SA2021

Stabilization of cultural innovations depends on population density: Testing an epidemiological model of cultural evolution against a global dataset of rock art sites and climate-based estimates of ancient population densities

John Richard Walker, Taylor Howard Newton, Francesco Casalegno

Demographic models of human cultural evolution have high explanatory potential but weak empirical support. Here we use a global dataset of rock art sites and climate and genetics-based estimates of ancient population densities to test a new model based on ...

2021

Dysmaturation Observed as Altered Hippocampal Functional Connectivity at Rest Is Associated With the Emergence of Positive Psychotic Symptoms in Patients With 22q11 Deletion Syndrome

Dimitri Nestor Alice Van De Ville, Maude Schneider, Daniela Maria Zöller, Farnaz Delavari, Karin Bortolin

BACKGROUND: Hippocampal alterations are among the most replicated neuroimaging findings across the psychosis spectrum. Moreover, there is strong translational evidence that preserving the maturation of hippocampal networks in mice models prevents the progr ...

ELSEVIER SCIENCE INC2021

Demography of galactic technosignatures

Claudio Grimaldi

Probabilistic arguments about the existence of technological life beyond Earth traditionally refer to the Drake equation to draw possible estimates of the number of technologically advanced civilizations releasing, either intentionally or not, electromagne ...

OXFORD UNIV PRESS2021

Critical review on bioconversion of winery wastes into value-added products

Edgard Gnansounou, Ranjna Sirohi

Global increase in the human population and life-style changes have led to enormous development in various industries, including beverage industry. Among the innumerable beverage industries, wineries have received increasing attention and consideration due ...

ELSEVIER2020

Time-lapse high-resolution microscopy to study the morphogenesis of microorganisms

Mélanie Thérèse Marie Hannebelle

Mycobacterium tuberculosis, the etiological agent for the tuberculosis disease, is a bacterial pathogen thought to infect about a quarter of the global human population. It is the first cause of death among infectious diseases, and is most prevalent in low ...

EPFL2020

An ecotoxicological view on neurotoxicity assessment

Wolfgang Schulz

The numbers of potential neurotoxicants in the environment are raising and pose a great risk for humans and the environment. Currently neurotoxicity assessment is mostly performed to predict and prevent harm to human populations. Despite all the efforts in ...

SPRINGEROPEN2018

Risk-Based Human-Aware Multi-Robot Coordination in Dynamic Environments Shared with Humans

Alcherio Martinoli, Zeynab Talebpour

In this paper, we propose a risk-based coordination method for the Multi-Robot Task Allocation (MRTA) problem in human-populated environments. We introduce risk-based bids that incorporate human trajectory prediction uncertainties and furthermore, social c ...

2018

KRAB'n'KAP, DNA methylation and epigenetic memory

Andrea Coluccio

The KZFP/KAP1 (Krüppel associated box zinc finger proteins/KRAB-associated protein 1) complex is a transcriptional repressor that triggers the deposition of heterochromatin (H3K9me3) and DNA methylation. The main targets of the KZFP/KAP1 complex are transp ...

EPFL2017

Rethinking Urban Form: Switzerland as a "Horizontal Metropolis"

Paola Viganò, Elena Cogato Lanza, Martina Barcelloni Corte, Chiara Cavalieri, Christian Arnsperger

In light of the rapid population growth forecast for the coming years and the powerful transformations already occurring throughout its whole territory, today's Switzerland stands in urgent need of critical reflection on its urban future. A novel set of co ...

Cogitatio Press2017

Mitochondrial DNA Analyses Indicate High Diversity, Expansive Population Growth and High Genetic Connectivity of Vent Copepods (Dirivultidae) across Different Oceans

Stefan Jean Laurent

Communities in spatially fragmented deep-sea hydrothermal vents rich in polymetallic sulfides could soon face major disturbance events due to deep-sea mineral mining, such that unraveling patterns of gene flow between hydrothermal vent populations will be ...

Public Library of Science2016

Performance assessment of pressurized fluid-distribution networks

Gaudenz Moser

Pressurized fluid-distribution networks are key strategic elements of infrastructure. Drinking water is a precious resource and will become more and more important with the depletion of reserves. With the growth of the human population, challenges related ...

EPFL2015

Environomic Design of Vehicle Integrated Energy System - Application on a Hybrid Electric Vehicle Energy System

François Maréchal, Zlatina Kirilova Dimitrova

With the increasing trend of mobility of the human population, vehicles have to face the problem of primary energy resources scarcity. The vehicles need higher efficiency and better adaptation to the alternative energy sources. The need to improve the effi ...

Aidic Servizi Srl2014

Comparison Between Reconstructions of Global Anthropogenic Land Cover Change over Past Two Millennia

Jed Oliver Kaplan, Jian Liu

Three global datasets, the History Database of the Global Environment (HYDE), Kaplan and Krumhardt (KK) and Pongratz of reconstructed anthropogenic land cover change (ALCC) were introduced and compared in this paper. The HYDE dataset was reconstructed by G ...

Springer2013

Robust Demographic Inference from Genomic and SNP Data

Matthieu Foll

We introduce a flexible and robust simulation-based framework to infer demographic parameters from the site frequency spectrum (SFS) computed on large genomic datasets. We show that our composite-likelihood approach allows one to study evolutionary models ...

Public Library of Science2013