Publications associées à Lipoprotéine de basse densité

Squalene Depletion in Skin Following Human Exposure to Ozone under Controlled Chamber Conditions

A major component of human skin oil is squalene, a highly unsaturated hydrocarbon that protects the skin from atmospheric oxidants. Skin oil, and thus squalene, is continuously replenished on the skin surface. Squalene is also quickly consumed through reac ...

Amer Chemical Soc2024

Model-based electron density estimation using multiple diagnostics on TCV

Olivier Sauter, Federico Alberto Alfredo Felici, Cristian Galperti

Estimation of the dynamic evolution of the electron plasma density during a tokamak discharge is crucial since it directly affects the plasma performance, confinement and stability. Therefore it needs to be monitored and controlled. Knowledge of the densit ...

ELSEVIER SCIENCE SA2023

Plant sterols and cholesterol metabolism are associated with five-year cognitive decline in the elderly population

Christopher Clark, Mehdi Gholam

Dysregulations in cholesterol metabolism are associated with neurodegenerative and vascular pathologies, and dementia. Diet-derived plant sterols (phytosterols) have cholesterol-lowering, anti-inflammatory, and antioxidant properties and may interfere with ...

CELL PRESS2023

Mitochondrial respiratory chain dysfunction disrupts intracellular cholesterol homeostasis

Christopher Tadhg James Wall

Mitochondrial diseases are rare and severe conditions with debilitating symptoms. Biochemical defects in mitochondria however are common. The difference between these two frequencies is suspected to lie in the capability of the cells to adapt to the homeos ...

EPFL2022

Investigation of Ethylene and Propylene Production from CO2 Reduction over Copper Nanocubes in an MEA-Type Electrolyzer

Raffaella Buonsanti, Valery Okatenko

Previous work carried out in fully liquid environ-ments and at low current densities has demonstrated that highly uniform faceted copper nanocrystals display different selectivity profiles in CO2 reduction compared to polycrystalline copper. As part of ong ...

AMER CHEMICAL SOC2022

Pollution mask for the continuous corrected particle number concentration data in 1 min resolution, measured in the Swiss aerosol container during MOSAiC 2019/2020

Julia Schmale, Ivo Fabio Beck, Andrea Baccarini, Hélène Paule Angot

This dataset contains a pollution flag in 1 min time resolution. It is derived by the pollution detection algorithm (PDA) based on the corrected particle number concentration data (DOI upcoming) measured during the year long MOSAiC expedition from October ...

Zenodo2022

TDCOSMO VII. Boxyness/discyness in lensing galaxies: Detectability and impact on H-0

Aymeric Alexandre Galan, Georgios Vernardos

In the context of gravitational lensing, the density profile of lensing galaxies is often considered to be perfectly elliptical. Potential angular structures are generally ignored, except to explain flux ratios of point-like sources (i.e. flux ratio anomal ...

EDP SCIENCES S A2022

Study of impurity ion transport using charge exchange spectroscopy on TCV

Filippo Bagnato

The study of impurity transport in fusion plasmas has gained interest over the years due to its implication with tokamak performances. In TCV (Tokamak à Configuration Variable), as in many other facilities, impurity ions can be studied through the CXRS (Ch ...

EPFL2022

Follicular regulatory helper T cells control the response of regulatory B cells to a high-cholesterol diet

Nikolaos Stergiopoulos

Aims B cell functions in the process of atherogenesis have been investigated but several aspects remain to be clarified. ...

OXFORD UNIV PRESS2021

Variations of intracellular density during the cell cycle arise from tip-growth regulation in fission yeast

Emrah Bostan, Pascal Damian Odermatt

Intracellular density impacts the physical nature of the cytoplasm and can globally affect cellular processes, yet density regulation remains poorly understood. Here, using a new quantitative phase imaging method, we determined that dry-mass density in fis ...

ELIFE SCIENCES PUBLICATIONS LTD2021

Experimental assessment of traffic density estimation at link and network level with sparse data

Nikolaos Geroliminis, Anna Takayasu

This paper investigates the accuracy of mean density estimation from direct sensing at link and network levels. Different calculation methods are compared depending on sensor type, probe vehicles or loop detectors, and availability to quantify the magnitud ...

TAYLOR & FRANCIS LTD2022

Counting People by Estimating People Flows

Pascal Fua, Mathieu Salzmann, Weizhe Liu

Modern methods for counting people in crowded scenes rely on deep networks to estimate people densities in individual images. As such, only very few take advantage of temporal consistency in video sequences, and those that do only impose weak smoothness co ...

2022

Cholesterol Hinders the Passive Uptake of Amphiphilic Nanoparticles into Fluid Lipid Membranes

Francesco Stellacci, Matteo Gasbarri, Ester Canepa, Giulia Rossi

Plasma membranes represent pharmacokinetic barriers for the passive transport of site-specific drugs within cells. When engineered nanoparticles (NPs) are considered as transmembrane drug carriers, the plasma membrane composition can affect passive NP inte ...

AMER CHEMICAL SOC2021

Measurement of the inner structure of turbidity currents by ultrasound velocity profiling

Giovanni De Cesare, Shun Nomura, Jumpei Hitomi

The inner velocity structure and particle concentration profile of opaque turbidity currents were mea- sured simultaneously by ultrasound velocity profilers. Currents consisting of a quartz particle suspension were generated by using the lock-exchange meth ...

2021

Passive and active ion permeation through lipid bilayers investigated by second harmonic water imaging

Maksim Eremchev

Lipid membranes are complex and dynamic systems which are known to mediate signaling processes between cells and their environment. To do this multiple ion channels and pumps are involved in controlling the in- and out-flux of various ions (K+, Na+, Mg2+, ...

EPFL2021

Cardiotrophin-1 Deficiency Abrogates Atherosclerosis Progression

Nikolaos Stergiopoulos, Rodrigo Araujo Fraga Da Silva

Cardiotrophin-1 (CT-1) is associated with cardiovascular (CV) diseases. We investigated the effect of CT-1 deficiency in the development and progression of atherosclerosis in double knockout Apoe(-/-)ct-1(-/-) mice. Apoe(-/-) C57Bl/6 or Apoe(-/-)ct-1(-/-) ...

Nature Research2020

Estimating People Flows to Better Count Them in Crowded Scenes

Pascal Fua, Mathieu Salzmann, Weizhe Liu

Modern methods for counting people in crowded scenes rely on deep networks to estimate people densities in individual images. As such, only very few take advantage of temporal consistency in video sequences, and those that do only impose weak smoothness co ...

2020

Polygenic modelling of treatment effect heterogeneity

Zhi Ming Xu

Mendelian randomization is the use of genetic variants to assess the effect of intervening on a risk factor using observational data. We consider the scenario in which there is a pharmacomimetic (i.e., treatment-mimicking) genetic variant that can be used ...

2020

L-Cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling

Kristina Schoonjans, Giovanni Sorrentino

Glucagon-like peptide 1 (GLP-1) mimetics are effective drugs for treatment of type 2 diabetes, and there is consequently extensive interest in increasing endogenous GLP-1 secretion and L-cell abundance. Here we identify G-protein-coupled bile acid receptor ...

AMER DIABETES ASSOC2020

Drug-induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann-Pick type C cells and mice

Marc Moniatte, Jonathan Paz Montoya

Most cells acquire cholesterol by endocytosis of circulating low-density lipoproteins (LDLs). After cholesteryl ester de-esterification in endosomes, free cholesterol is redistributed to intracellular membranes via unclear mechanisms. Our previous work sug ...

2019