Publications associées à Chlamydomonas reinhardtii

Disturbed mitochondrial dynamics in CD8(+)TILs reinforce T cell exhaustion

Li Tang, Nicola Vannini, George Coukos, Marcela Rincón-Restrepo, Min Gao, Fabien Franco

Ho and colleagues report that mitochondrial dysfunction and impaired mitophagy triggered by the tumor microenvironment lead to subsequent epigenetic changes and cause permanent T cell exhaustion and dysfunction. The metabolic challenges present in tumors a ...

2020

A synthetic biology approach to engineering living photovoltaics

Ardemis Anoush Boghossian, Nils Schürgers

The ability to electronically interface living cells with electron accepting scaffolds is crucial for the development of next-generation biophotovoltaic technologies. Although recent studies have focused on engineering synthetic interfaces that can maximiz ...

Royal Soc Chemistry2017

Pro-oxidant effects of nano-TiO2 on Chlamydomonas reinhardtii during short-term exposure

Olivier Martin, Paul Bowen, Christian Santschi, Lionel André Maurizi, Volodymyr Koman, Nadia Rachel Von Moos, Amarnath Jayaprakash

This study sheds light on the short-term dynamics of pro-oxidant processes related to the exposure of C. reinhardtii microalgae to nano-TiO2 using (a) conventional fluorescence probes for cellular pro-oxidant process and (b) a recently developed cytochrome ...

Royal Soc Chemistry2016

Multiscattering-enhanced optical biosensor: multiplexed, non-invasive and continuous measurements of cellular processes

Christian Santschi, Olivier Martin, Volodymyr Koman

The continuous measurement of uptake or release of biomarkers provides invaluable information for understanding and monitoring the metabolism of cells. In this work, a multiscattering-enhanced optical biosensor for the multiplexed, non-invasive, and contin ...

Optical Soc Amer2015

Interactions of silver and polystyrene nanoparticles with algae

Xiaomei Li

Nanoparticles have various physicochemical properties attributed by their small dimensions. The global production of nanoparticles lead to a raised concern for their environmental impacts. Algae are of highly ecological importance functioning as primary pr ...

EPFL2015

Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype of Chlamydomonas reinhardtii exposed to silver

Kristin Schirmer, Laura Sigg, Renata Behra

Understanding mechanistic and cellular events underlying a toxicological outcome allows the prediction of impact of environmental stressors to organisms living in different habitats. A systems-based approach aids in characterizing molecular events, and the ...

National Academy of Sciences2014

Correlative multicolor 3D SIM and STORM microscopy

Pierre Gönczy, Arne Seitz, Paul Guichard, Romain Guiet, Virginie Hamel, Isabelle Fluckiger, Mathias Fournier

Within the last decade, super-resolution methods that surpass the diffraction limit of light microscopy have provided invaluable insight into a variety of biological questions. Each of these approaches has inherent advantages and limitations, such that the ...

Optical Soc Amer2014

Degradation of Eight Relevant Micropollutants in Different Water Matrices by Neutral Photo-Fenton Process under UV254 and Simulated Solar Light Irradiation – a comparative study

César Pulgarin, Andrzej Sienkiewicz, Dominique Grandjean, Luiz Felippe De Alencastro

This is a comparative study of photolytic degradation under exposure to UV254 nm and solar-simulator irradiation of a mixture of eight equally concentrated relevant micropollutants in the presence of H2O2 and Fe(II) in ultrapure water, Lake Geneva water, a ...

Elsevier Science Bv2014

Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry

Pierre Gönczy, Virginie Hamel, Georgios Hatzopoulos, Paul Guichard, Isabelle Fluckiger

Centrioles are evolutionary conserved organelles that give rise to cilia and flagella as well as centrosomes. Centrioles display a characteristic ninefold symmetry imposed by the spindle assembly abnormal protein 6 (SAS-6) family. SAS-6 from Chlamydomonas ...

2013

Sensing the dynamics of oxidative stress using enhanced absorption in protein-loaded random media

Olivier Martin, Christian Santschi, Guillaume Suarez

Reactive oxygen species play a key role in cell signalling and oxidative stress mechanisms, therefore, sensing their production by living organisms is of fundamental interest. Here we describe a novel biosensing method for extracellular detection of endoge ...

Nature Publishing Group2013

Multiple-endpoint assay provides a detailed mechanistic view of responses to herbicide exposure in Chlamydomonas reinhardtii

Kristin Schirmer, Renata Behra

The release of herbicides into the aquatic environment raises concerns about potential detrimental effects on ecologically important non-target species, such as unicellular algae, necessitating ecotoxicological risk assessment. Algal toxicity tests based o ...

2012

Cell-wall-dependent effect of carboxyl-CdSe/ZnS quantum dots on lead and copper availability to green microalgae

Miguel Garcia

The present study examines the effect of carboxyl-CdSe/ZnS quantum dots (QDs) on Cu and PI) availability to microalgae with different cell wall characteristics: Chlorella kesslerii possessing a cellulosic cell wall and two strains of Chlamydomonas reinhard ...

2012