Concept

Alcohol dependence

Publications associées (26)

Artificial intelligence of things for smart cities: advanced solutions for enhancing transportation safety

In the context of smart cities, ensuring road safety is crucial due to increasing urbanization and the interconnected nature of contemporary urban environments. Leveraging innovative technologies is essential to mitigate risks and create safer communities. ...

Springernature2024

Medical and Personal Characteristics Can Predict the Risk of Lung Metastasis

Michele De Palma, Nahal Mansouri

Aims: Understanding the correlations between underlying medical and personal characteristics of a patient with cancer and the risk of lung metastasis may improve clinical management and outcomes. We used machine learning methodologies to predict the risk o ...

2023

Measuring electro-adhesion pressure before and after contact

Herbert Shea, Sylvain Thomas Schaller

Electro-adhesion (EA) is a low-power, tunable, fast and reversible electrically-controlled adhesion method, effective on both conducting and insulating objects. Typically, only the electro-adhesive detachment force, i.e., the force required to separate an ...

Nature Portfolio2023

Dopamine Transporter, PhosphoSerine129 alpha-Synuclein and alpha-Synuclein Levels in Aged LRRK2 G2019S Knock-In and Knock-Out Mice

Salvatore Novello, Chiara Domenicale

The G2019S mutation in leucine rich-repeat kinase 2 (LRRK2) is a major cause of familial Parkinson's disease. We previously reported that G2019S knock-in mice manifest dopamine transporter dysfunction and phosphoSerine129 alpha-synuclein (pSer129 alpha-syn ...

MDPI2022

Impaired cognitive flexibility and heightened urgency are associated with increased alcohol consumption in rodent models of excessive drinking

Emanuela De Falco

Alcohol use disorder (AUD) is characterized by impairments in decision-making that can exist as stable traits or transient states. Cognitive inflexibility reflects an inability to update information that guides decision-making and is thought to contribute ...

WILEY2021

Is a Single Conformer Sufficient to Describe the Reorganization Energy of Amorphous Organic Transport Materials?

Anne-Clémence Corminboeuf, Iwona Swiderska, Kun-Han Lin, Raimon Fabregat I De Aguilar-Amat, Jacob Terence Blaskovits, Hélène Wu

The reorganization energy (lambda), which quantifies the structural rearrangement of a molecule when accommodating a charge, is a key parameter in the evaluation of charge mobility in molecular solids. However, it is unclear how lambda is influenced by con ...

AMER CHEMICAL SOC2021

Dynamics of optical forces and torques in plasmonic systems: a surface integral equation

Olivier Martin, Karim Achouri, Andrei Kiselev

A novel approach is introduced to determine the time evolution of optical forces and torques on arbitrary shape nanostructures by combining Maxwell's stress tensor with the surface integral equation method (SIE). Conventional time averaging of Maxwell’s st ...

SPIEDigitalLibrary2020

Inference on the Angular Distribution of Extremes

Claudio Andri Semadeni

The spectral distribution plays a key role in the statistical modelling of multivariate extremes, as it defines the dependence structure of multivariate extreme-value distributions and characterizes the limiting distribution of the relative sizes of the co ...

EPFL2020

The contexts of heavy drinking: A systematic review of the combinations of context-related factors associated with heavy drinking occasions

Background The amount of alcohol consumed during an occasion can be influenced by physical and social attributes of the setting, characteristics and state of individuals, and the interactions of these components. This systematic review identifies and descr ...

2019

Crystal Orientation Drives the Interface Physics at Two/Three-Dimensional Hybrid Perovskites

Jacques-Edouard Moser, Mohammad Khaja Nazeeruddin, Sanghyun Paek, Giulia Grancini, Kyung Taek Cho, Cristina Roldán Carmona, Valentin Ianis Emmanuel Queloz, Marine Eva Fedora Bouduban

Combining halide perovskites with tailored dimensionality into two/three-dimensional (2D/3D) systems has revealed a powerful strategy to boost the performances of perovskite photovoltaics (PVs). Despite recent advances, a clear understanding of the intimat ...

2019

Exploration and Inference in Spatial Extremes Using Empirical Basis Functions

Emeric Rolland Georges Thibaud

Statistical methods for inference on spatial extremes of large datasets are yet to be developed. Motivated by standard dimension reduction techniques used in spatial statistics, we propose an approach based on empirical basis functions to explore and model ...

SPRINGER2019

On the benefits of a stress criterion for the simulation of cup drawing process

Roland Logé

Experimental and numerical cup drawing process has been investigated on 0.65 mm zinc sheets. The cup exhibits anisotropic earrings due to the material microstructure. The material formability is studied through elliptical bulge tests in the rolling, diagon ...

Springer France2018

After how many drinks does someone experience acute consequences-determining thresholds for binge drinking based on two event-level studies: Optimal thresholds for binge drinking

Background and Aims: The threshold of 4+/5+ drinks per occasion has been used for decades in alcohol research to distinguish between non risky versus risky episodic drinking. However, no study has assessed the validity of this threshold using event level d ...

2018

Semiparametric Bayesian Risk Estimation for Complex Extremes

Thomas Lugrin

Extreme events are responsible for huge material damage and are costly in terms of their human and economic impacts. They strike all facets of modern society, such as physical infrastructure and insurance companies through environmental hazards, banking an ...

EPFL2018

A preclinical model for identifying rats at risk of alcohol use disorder

Pierre Magistretti, Benjamin Boutrel

Alcohol use is one of the world's leading causes of death and disease, although only a small proportion of individuals develop persistent alcohol use disorder (AUD). The identification of vulnerable individuals prior to their chronic intoxication remains o ...

Springer Nature2017

Robust Bounds In Multivariate Extremes

Sebastian Engelke

Extreme value theory provides an asymptotically justified framework for estimation of exceedance probabilities in regions where few or no observations are available. For multivariate tail estimation, the strength of extremal dependence is crucial and it is ...

Institute of Mathematical Statistics2017

Pressure-dependent elastic and transport properties of porous and permeable rocks: Microstructural control

Lucas Xan Pimienta, Christian David

Although several studies aimed at linking electrical and hydraulic transport properties in rocks, the existing models remain at most incomplete. Based on this observation, in addition to the transport properties, this contribution investigates the pressure ...

Amer Geophysical Union2017

Time-Dependent Diffusion MRI in Cancer: Tissue Modeling and Applications

Olivier Benoit Thomas Reynaud

In diffusion weighted imaging (DWI), the apparent diffusion coefficient (ADC) has been recognized as a useful and sensitive surrogate for cell density, paving the way for non-invasive tumor staging, and characterization of treatment efficacy in cancer. How ...

Frontiers Research Foundation2017

Bayesian uncertainty management in temporal dependence of extremes

Anthony Christopher Davison, Thomas Lugrin, Jonathan A. Tawn

Both marginal and dependence features must be described when modelling the extremes of a stationary time series. There are standard approaches to marginal modelling, but long-and short-range dependence of extremes may both appear. In applications, an assum ...

Springer Verlag2016

Time-dependent correlations in quantum magnets at finite temperature

Thomas Keller, Felix Groitl

In this Rapid Communication we investigate the time dependence of the gap mode of copper nitrate at various temperatures. We combine state-of-the-art theoretical calculations with high precision neutron resonance spin-echo measurements to understand the an ...

Amer Physical Soc2016