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Publications associées (30)

Brain Perfusion Measurements Using Multidelay Arterial Spin-Labeling Are Systematically Biased by the Number of Delays

Dimitri Nestor Alice Van De Ville, Nicolas Gninenko, Merel Margaretha van der Thiel

BACKGROUND AND PURPOSE:Multidelay arterial spin-labeling is a promising emerging method in clinical practice. The effect of imaging parameters in multidelay arterial spin-labeling on estimated cerebral blood flow measurements remains unknown. We directly c ...

AMER SOC NEURORADIOLOGY2018

In vivo (13)C MRS in the mouse brain at 14.1 Tesla and metabolic flux quantification under infusion of [1,6-(13)C2]glucose

Rolf Gruetter, Cristina Ramona Cudalbu, Bernard Lanz, Carole Poitry-Yamate, Marta Lai, Corina Mihaela Berset

In vivo (13)C magnetic resonance spectroscopy (MRS) enables the investigation of cerebral metabolic compartmentation while, e.g. infusing (13)C-labeled glucose. Metabolic flux analysis of (13)C turnover previously yielded quantitative information of glutam ...

2018

Implantable IoT System for Closed-Loop Epilepsy Control based on Electrical Neuromodulation

Alexandre Schmid, Reza Ranjandish

A closed-loop system aiming at epilepsy control is proposed in this paper, in which electrical stimulation is triggered upon a decision aggragating different biological signatures of the seizure such as changes in the heart rate, blood flow in the brain, a ...

IEEE2018

A Multifaceted Approach to Covert Attention Brain-Computer Interfaces

Christoph Schneider

Over the last years, brain-computer interfaces (BCIs) have shown their value for assistive technology and neurorehabilitation. Recently, a BCI-approach for the rehabilitation of hemispatial neglect has been proposed on the basis of covert visuospatial atte ...

EPFL2018

In vivo neurochemical measurements in cerebral tissues using a droplet-based monitoring system

Philippe Renaud, Guillaume Cédric Yves Petitpierre, Bernard Schneider, Arnaud Bertsch, Philippe Colin, Aurélien Thomas

Direct collection of extracellular fluid (ECF) plays a central role in the monitoring of neurological disorders. Current approaches using microdialysis catheters are however drastically limited in term of temporal resolution. Here we show a functional in v ...

Nature Publishing Group2017

Lactate and Glutamate dynamics during prolonged stimulation of the rat barrel cortex suggest adaptation of cerebral glucose and oxygen metabolism

Nathalie Just, João Miguel das Neves Duarte, Sarah Catherine Sonnay

A better understanding of BOLD responses stems from a better characterization of the brain’s ability to metabolize glucose and oxygen. Non-invasive techniques such as functional magnetic resonance spectroscopy (fMRS) have thus been developed allowing for t ...

Elsevier2017

Hyperpolarized MRS: New tool to study real-time brain function and metabolism

Mor-Miri Mishkovsky, Arnaud Comment

The advent of dissolution dynamic nuclear polarization (DNP) led to the emergence of a new kind of magnetic resonance (MR) measurements providing the opportunity to probe metabolism in vivo in real time. It has been shown that, following the injection of h ...

Elsevier2017

A Microfluidic Brain Interface for In Vivo Recording of Neurochemical Activity

Guillaume Cédric Yves Petitpierre

Neurological disorders have a strong negative impact on the quality of life of affected patients, their close relatives as well as on the health economic system. Early diagnosis associated with better treatment outcomes remain difficult to reach. Similarly ...

EPFL2017

In vivo cerebral metabolism of glioblastoma xenografts assessed with ¹H MRS, ¹³C MRS and ¹⁸F-FDG PET

Marta Lai

Magnetic resonance spectroscopy (MRS) is a powerful tool when studying metabolism in intact and living organs preserving cells in their natural microenvironment with minimal external interference. The unique insights offered by the observation of metabolic ...

EPFL2017

Study of cortical energy metabolism during sensory stimulation-induced brain activity by ¹³C magnetic resonance spectroscopy in vivo

Sarah Catherine Sonnay

Cerebral function is associated with high metabolic activity that is supported by continuous supply of oxygen and glucose from the blood. Coupling between brain energy metabolism and neuronal activity has been studied extensively during the past decades. N ...

EPFL2017

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