Métabolisme acido-basique

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Publications associées (31)

Cytosolic Proteostasis Networks of the Mitochondrial Stress Response

Johan Auwerx, Davide D'Amico, Vincenzo Sorrentino

Mitochondrial stress requires timely intervention to prevent mitochondria' and cellular dysfunction. Re-establishing the correct protein homeostasis is crucial for coping with mitochondria' stress and maintaining cellular homeostasis. The best-characterize ...

Elsevier Science London2017

The role of nicotinamide riboside kinases in mammalian NAD⁺ metabolism

Joanna Ratajczak

NAD+ has emerged as a central metabolic node and an important co-substrate for the activity of various enzymes, including the protein deacetylase SIRT1. Different strategies to increase NAD+ bioavailability have been shown to boost SIRT1 activity, which re ...

EPFL2017

Modeling Hsp70/Hsp40 interaction by multi-scale molecular simulations and co-evolutionary sequence analysis

Paolo De Los Rios, Alessandro Barducci, Duccio Malinverni

The interaction between the Heat Shock Proteins 70 and 40 is at the core of the ATPase regulation of the chaperone machinery that maintains protein homeostasis. However, the structural details of the interaction are still elusive and contrasting models hav ...

Elife Sciences Publications Ltd2017

Protons and Hydroxide Ions in Aqueous Systems

Sylvie Roke

Understanding the structure and dynamics of water's constituent ions, proton and hydroxide, has been a subject of numerous experimental and theoretical studies over the last century. Besides their obvious importance in acid-base chemistry, these ions play ...

American Chemical Society2016

Influence of TiO2 phase composition on the photocatalytic activity of TiO2/MWCNT composites prepared by combined sol-gel/hydrothermal method

László Forró, Arnaud Magrez, Endre Horvath, Klara Hernadi

Titanium dioxide/multiwall carbon nanotube (TiO2/MWCNT) composites were prepared by sol-gel method with hydrolysis of titanium alkoxide precursor followed by crystallization via hydrothermal treatment at different acid concentrations. Transmission electron ...

Elsevier Science Bv2016

New insights into ROS dynamics: a multi-layered microfluidic chip for ecotoxicological studies on aquatic microorganisms

Olivier Martin, Christian Santschi, Volodymyr Koman, Nadia Rachel Von Moos

Reactive oxygen species (ROS) play an important role in the life of every cell, including cellular defense and signaling mechanisms. Continuous and quantitative ROS sensing can provide valuable information about the cell state, but it remains a challenge t ...

Informa Healthcare2016

Multiscattering-enhanced optical probes for biosensing

Volodymyr Koman

Although reactive oxygen species (ROS) are an inescapable part of every living organism, we are only beginning to understand their functions and mechanics. As of now, we know that ROS are involved in cell signalling, stress-response and defence against pat ...

EPFL2015

Shift from heterogeneous to homogeneous catalysis during resorcinol degradation using the solar photo-Fenton process initiated at circumneutral pH

César Pulgarin, Luis Ferney Gonzalez Bahamon

The photo-Fenton process (Fe-2+,Fe-3+/H2O2/hv) is known to degrade aqueous organic compounds at acidic pHs. Nevertheless, recent studies have shown that this process also occurs at circumneutral pHs. Dihydroxybenzene isomers (i.e., resorcinol, hydroquinone ...

Elsevier Science Bv2015

A Pyridine-Based Ligand with Two Hydrazine Functions for Lanthanide Chelation: Remarkable Kinetic Inertness for a Linear, Bishydrated Complex

Lothar Helm, Eva Jakab Toth

To study the influence of hydrazine functions in the ligand skeleton, we designed the heptadentate HYD ligand (2,2',2 '',2 ''-(2,2'-(pyridine-2,6-diyl)bis(2-methylhydrazine-2,1,1-triyl)) tetraacetic acid) and compared the thermodynamic, kinetic, and relaxa ...

American Chemical Society2015

The Influence of Arginine on the Response of Enamel Matrix Derivative (EMD) Proteins to Thermal Stress: Towards Improving the Stability of EMD-Based Products

John Christopher Plummer, Matteo Gregorio Modesto Marascio, Alessandra Apicella, Raffaele Mezzenga, Peter Fischer

In a current procedure for periodontal tissue regeneration, enamel matrix derivative (EMD), which is the active component, is mixed with a propylene glycol alginate (PGA) gel carrier and applied directly to the periodontal defect. Exposure of EMD to physio ...

Public Library Science2015

Portable oxidative stress sensor: Dynamic and non-invasive measurements of extracellular H2O2 released by algae

Christian Santschi, Olivier Martin, Volodymyr Koman

Reactive oxygen species (ROS) generated by aerobic organisms are essential for physiological processes such as cell signaling, apoptosis, immune defense and oxidative stress mechanisms. Unbalanced oxidant/antioxidant budgets are involved in many diseases a ...

Elsevier2015

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