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Publications associées (27)

Lansoprazole is an antituberculous prodrug targeting cytochrome bc1

Stewart Cole, Florence Pojer, Claudia Sala, Andrej Benjak, Anthony Vocat, Philippe Busso, Jan Lars Rybniker

Better antibiotics capable of killing multi-drug-resistant Mycobacterium tuberculosis are urgently needed. Despite extensive drug discovery efforts, only a few promising candidates are on the horizon and alternative screening protocols are required. Here, ...

Nature Publishing Group2015

Deciphering the astrocyte-neuron metabolic cooperation in vivo

Manuel Raphael Zenger

Brain energy consumption is high and a very tightly regulated energy metabolism ensures correct performance. Neurons, the cells responsible for transmitting information via synapses, interact very closely with star shaped glial cells called astrocytes. Ast ...

EPFL2015

Light Transport Matrix recovery for nearly planar objects

Martin Vetterli, Paolo Prandoni, Loïc Arnaud Baboulaz, Niranjan Thanikachalam

The light transport matrix has become a powerful tool for scene relighting, owing to the versatility of its representational power of various light transport phenomenon. We argue that scenes with an almost planar surface geometry, even with significant amo ...

SPIE2014

Mechanism of oxygen reduction by metallocenes near liquid|liquid interfaces

Hubert Girault, Pekka Eero Peljo, Thomas James Stockmann, Haiqiang Deng

The mechanism of the oxygen reduction reaction (ORR) at a liquid|liquid interface, employing ferrocene (Fc) derivatives – such as decamethylferrocene (DMFc) – as a lipophilic electron donor along with sulfuric acid as an aqueous proton source, was elucidat ...

Elsevier2014

Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2

Matteo Dal Peraro, Thomas Lemmin, Anna Vestergaard

P4-ATPases (flippases) translocate specific phospholipids such as phosphatidylserine from the exoplasmic leaflet of the cell membrane to the cytosolic leaflet, upholding an essential membrane asymmetry. The mechanism of flipping this giant substrate has re ...

National Academy of Sciences2014

A microfluidic flow-cell for the study of the ultrafast dynamics of biological systems

Majed Chergui, Adrien Alexis Paul Chauvet

The study of biochemical dynamics by ultrafast spectroscopic methods is often restricted by the limited amount of liquid sample available, while the high repetition rate of light sources can induce photodamage. In order to overcome these limitations, we de ...

American Institute of Physics2014

Viscoelastic phase diagram of fluorinated and grafted polymer films and proton-exchange membranes for fuel cell applications

Yves Leterrier

The influence of temperature and moisture activity on the viscoelastic behavior of fluorinated membranes for fuel cell applications was investigated. Uncrosslinked and crosslinked ethylene tetrafluoroethylene (ETFE)-based proton-conducting membranes were p ...

2013

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