Pharmacocinétique

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Publications associées (29)

Single-cell division and killing dynamics of bacteria exposed to isocratic and time-dependent concentrations of antibiotic

Katrin Esther Schneider

Antibiotic resistance, defined as the ability of a bacteria to survive an antibiotic drug to which it was initially sensitive, has become increasingly worrying. While the discovery of antibiotics is considered to be one of the most important of all biomedi ...

EPFL2018

Nanoparticle-Enhanced Plasmonic Biosensor for Digital Biomarker Detection in a Microarray

Hatice Altug, Alexander Belushkin, Filiz Yesilköy

Nanoplasmonic devices have become a paradigm for biomolecular detection enabled by enhanced light–matter interactions in the fields from biological and pharmaceutical research to medical diagnostics and global health. In this work, we present a bright-fiel ...

2018

Observation of enhanced ion particle transport in mixed H/D isotope plasmas on JET

Olivier Sauter, Ambrogio Fasoli, Basil Duval, Stefano Coda, Martinus Gijs, Jonathan Graves, Yves Martin, Duccio Testa, Patrick Blanchard, Bruno Emanuel Ferreira De Sousa Correia, Alessandro Pau, Pierre-Thomas Paul Brun, Cristian Sommariva, Henri Weisen, Michele Marin, Richard Pitts, Sun Hee Kim, Yann Camenen, Jan Horacek, Marco Wischmeier, Javier García Hernández, Mikhail Maslov, Miguel Fernández Ruiz, Nicola Vianello, Antonio José Pereira de Figueiredo, Federico Nespoli, Liang Yao, Dalziel Joseph Wilson, Yao Zhou, Robin Humphry-Baker, David Pfefferlé, José Pedro Rebelo Ferreira Marques, Davide Galassi, Ana Francisca Leal Silva Soares, Daniel Scott Alessi, Jonathan Marc Philippe Faustin, Arnout Lodewijk M Beckers, Julio Rodriguez, Jonnathan Cesar Hidalgo Acosta, Hamish William Patten, , , , , , , , ,

Intra- and extra-axonal axial diffusivities in the white matter: Which one is faster?

Ileana Ozana Jelescu, Nicolas Kunz

A two-compartment model of diffusion in white matter, which accounts for intra- and extra-axonal spaces, is associated with two plausible mathematical scenarios: either the intra-axonal axial diffusivity Da,‖ is higher than the extra-axonal De,‖ (Branch 1) ...

2018

Removal of pharmaceuticals in pre-denitrifying MBBR Influence of organic substrate availability in single- and three-stage configurations

Luca Loreggian

Due to the limited efficiency of conventional biological treatment, innovative solutions are being explored to improve the removal of trace organic chemicals in wastewater. Controlling biomass exposure to growth substrate represents an appealing option for ...

Pergamon-Elsevier Science Ltd2017

Constrained multi-rate state estimator incorporating delayed measurements

Dominique Bonvin, Michael Amrhein, Sriniketh Srinivasan

Frequent and accurate concentration estimates are important for the on-line control and optimization of chemical reaction systems. Such estimates can be obtained using state estimation methods that fuse frequent (fast) delay-free on-line measurements with ...

IEEE2017

TUCUXI: TUCUXI: An Intelligent System for Personalized Medicine from Individualization of Treatments to Research Databases and Back

Karl Aberer, Alevtina Dubovitskaya, Yann Thoma, Michael Ignaz Schumacher, Thierry Buclin

Therapeutic Drug Monitoring (TDM) is a key concept in precision medicine. The goal of TDM is to avoid therapeutic failure or toxic effects of a drug due to insufficient or excessive circulating concentration exposure related to between-patient variability ...

2017

Controlling and Monitoring Intracellular Delivery of Anticancer Polymer Nanomedicines

Harm-Anton Klok, Claudia Battistella

Polymer nanomedicines are very attractive to improve the delivery of chemotherapeutics. Polymer conjugates and other polymer-based nanocarriers allow to increase plasma half-life and drug bioavailability and can also be guided toward tumors using passive a ...

2017

Lactate and Glutamate dynamics during prolonged stimulation of the rat barrel cortex suggest adaptation of cerebral glucose and oxygen metabolism

Nathalie Just, João Miguel das Neves Duarte, Sarah Catherine Sonnay

A better understanding of BOLD responses stems from a better characterization of the brain’s ability to metabolize glucose and oxygen. Non-invasive techniques such as functional magnetic resonance spectroscopy (fMRS) have thus been developed allowing for t ...

Elsevier2017

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Li Shuai

Samuel Lanthaler

Pedro Camilo de Oliveira e Silva

Alberto Hernando de Castro

Particle transport in tokamak plasmas has been intensively studied in the past, particularly in relation to density peaking and the presence of anomalous inward particle convection in L-and H-modes. While in the L-mode case the presence of the anomalous in ...

IOP Publishing Ltd2018