Publications associées à Variation naturelle

Waterborne Virus Transport and Risk Assessment in Lake Geneva Under Climate Change

Climate changes influence lake hydrodynamics and radiation levels and thus may affect the fate and transport of waterborne pathogens in lakes. This study examines the impact of climate change on the fate, transport, and associated risks of four waterborne ...

2024

Decision support methodology for waste-to-value process integration

Rafael Amorim Leandro De Castro Amoedo

Waste treatment is a complex procedure that comprises multidimensional aspects. The challenges posed by the energy transition and international protocols emphasize the role of waste in its material and energy dimension. With an increasing population and li ...

EPFL2023

Distributed Lossy Computation with Structured Codes: From Discrete to Continuous Sources

Michael Christoph Gastpar, Sung Hoon Lim, Adriano Pastore, Chen Feng

This paper considers the problem of distributed lossy compression where the goal is to recover one or more linear combinations of the sources at the decoder, subject to distortion constraints. For certain configurations, it is known that codes with algebra ...

2023

Impact of population size on early adaptation in rugged fitness landscapes

Anne-Florence Raphaëlle Bitbol, Richard Marie Servajean

Owing to stochastic fluctuations arising from finite population size, known as genetic drift, the ability of a population to explore a rugged fitness landscape depends on its size. In the weak mutation regime, while the mean steady-state fitness increases ...

ROYAL SOC2023

The end of urban sprawl? Internal migration across the rural-urban continuum in Switzerland, 1966-2018

Mathias Lerch

In high-income countries, migration redistributed populations from congested city centres into the sparsely populated outskirts, raising challenges to environmental and population health and the conservation of biodiversity. We evaluate whether this periur ...

2023

Shannon Bounds on Lossy Gray-Wyner Networks

Michael Christoph Gastpar, Erixhen Sula

The Gray-Wyner network subject to a fidelity criterion is studied. Upper and lower bounds for the trade-offs between the private sum-rate and the common rate are obtained for arbitrary sources subject to mean-squared error distortion. The bounds meet exact ...

2022

A birth-death-migration model for life in astrophysical environments

Claudio Grimaldi

To assess the number of life-bearing worlds in astrophysical environments, it is necessary to take the intertwined processes of abiogenesis (birth), extinction (death), and transfer of life (migration) into account. We construct a mathematical model that i ...

OXFORD UNIV PRESS2021

Investigating Crosstalk Among PTMs Provides Novel Insight Into the Structural Basis Underlying the Differential Effects of Nt17 PTMs on Mutant Httex1 Aggregation

Hilal Lashuel, Matteo Dal Peraro, Luciano Andres Abriata, Lucien Fabrice Krapp, Anass Chiki, Driss Boudeffa, Iman Rostami, Rajasekhar Kolla, Zhidian Zhang

Post-translational modifications (PTMs) within the first 17 amino acids (Nt17) of the Huntingtin protein (Htt) have been shown to inhibit the aggregation and attenuate the toxicity of mutant Htt proteins in vitro and in various models of Huntington’s disea ...

2021

International Migration And The Growth Of Zurich, 1836-1949

Mathias Lerch

The role played by international migration and its interactions with other demographic components in the process of city growth remains underappreciated. We analyze trends in natural increase and in net internal and international migration in Zurich during ...

2021

Pressure on obstacles induced by granular snow avalanches

Michael Lukas Kyburz

The increasing population and the consequential demand for dwelling and recreation areas lead to more frequent conflicts between humans and natural hazards. In mountainous regions snow avalanches are, therefore, still a major threat to humans and infrastru ...

EPFL2021

Adapt or Perish: Evolutionary Rescue in a Gradually Deteriorating Environment

Anne-Florence Raphaëlle Bitbol, Loïc Marrec

We investigate the evolutionary rescue of a microbial population in a gradually deteriorating environment, through a combination of analytical calculations and stochastic simulations. We consider a population destined for extinction in the absence of mutan ...

2020

The population genetics of crypsis in vertebrates: recent insights from mice, hares, and lizards

Jeffrey David Jensen, Kristen Kay Irwin, Susanne Petra Pfeifer, Stefan Jean Laurent

By combining well-established population genetic theory with high-throughput sequencing data from natural populations, major strides have recently been made in understanding how, why, and when vertebrate populations evolve crypsis. Here, we focus on backgr ...

NATURE PUBLISHING GROUP2020

New architecture for the analog front-end of Medipix4

Jean-Michel Sallese, Adil Koukab, Viros Sriskaran

The Medipix4 chip is the latest member of the family of Medipix pixel detector readout chips aimed at high rate spectroscopic X-ray imaging. Unlike its predecessors, it will be possible to tile the chip on all 4 sides permitting seamless large area coverag ...

ELSEVIER2020

Multidisciplinary Approach to Treat Erectile Dysfunction

Mikaël Nils Sturny

Erectile dysfunction (ED) is a widespread disease affecting approximately 20% of men. With a rising incidence due to the global ageing of the world population, it is estimated that over 322 million patients will be affected in 2025. While not being a lifet ...

EPFL2020

Resist or perish: Fate of a microbial population subjected to a periodic presence of antimicrobial

Anne-Florence Raphaëlle Bitbol, Loïc Marrec

The evolution of antimicrobial resistance can be strongly affected by variations of antimicrobial concentration. Here, we study the impact of periodic alternations of absence and presence of antimicrobial on resistance evolution in a microbial population, ...

2020

The Minimization of Public Facilities With Enhanced Genetic Algorithms Using War Elimination

Michael Mark

In this paper, we focus on the problem of minimizing a network of state facilities that provide essential public services (schools, offices, and hospitals). The goal is to reduce the size of the network in order to minimize the costs associated with it. Ho ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2019

Formation Rules and Dynamics of Photoinduced χ(2) Gratings in Silicon Nitride Waveguides

Tobias Kippenberg, Camille Sophie Brès, Davide Grassani, Martin Hubert Peter Pfeiffer, Edgars Nitiss, Tianyi Liu

Silicon nitride has emerged as a prominent platform for building photonics integrated circuits. While its nonlinear properties based on third-order effects have been successfully exploited, an efficient second harmonic generation in standard stoichiometric ...

2020

Effects of altered river network connectivity on the distribution of Salmo trutta: Insights from a metapopulation model

Andrea Rinaldo, Enrico Bertuzzo, Luca Carraro, Alexia Maria Gonzalez Ferreras

Network connectivity is a key feature of rivers that affects patterns and processes in lotic ecosystems. Few studies have considered how changes in river reach connectivity might affect ecosystem attributes at a whole river network scale. The use of popula ...

WILEY2019

No Evidence for a Common Factor Underlying Visual Abilities in Healthy Older People

Michael Herzog, Aline Françoise Cretenoud, Aaron Michael Clarke, Albulena Jashari-Shaqiri

The world's population is aging at an increasing rate. Even in the absence of neurodegenerative disorders, healthy aging affects perception and cognition. In the context of cognition, common factors are well established. Much less is known about common fac ...

AMER PSYCHOLOGICAL ASSOC2019

Impact of material properties on caprock stability in CO2 geological storage

Lyesse Laloui, Chao Li

In this study, thermo-hydro-mechanical coupled simulations are performed to investigate caprock stability under cooling and pressurization during the injection of carbon dioxide. It is shown that failure potential of caprock increases with a higher value o ...

Elsevier Science Bv2017