Publications de Samuel Terrettaz

Monitoring proliferative activities of hormone-like odorants in human breast cancer cells by gene transcription profiling and electrical impedance spectroscopy

Horst Vogel, Samuel Terrettaz, Horst Pick, Olivia Baud, Cathrin Brisken

The human estrogen receptor alpha (ER!) mediates the proliferative action of hormones in breast cancer cells by regulating the expression of target genes to control cellular functions. Current methodologies do not permit a real-time assessment of these pro ...

Elsevier2013

A synthetic membrane protein in tethered lipid bilayers for immunosensing in whole blood

Solomzi Makohliso, Horst Vogel, Samuel Terrettaz, Stéphanie Follonier

Tethered lipid bilayers, containing a transmembrane synthetic ligand-gated ion channel (SLIC), have been formed on gold surfaces. The SLIC was designed as a highly selective receptor and reporter protein to detect antibodies in whole blood, which are of im ...

Elsevier2009

Probing the function of ionotropic and G protein-coupled receptors in surface-confined membranes

Horst Vogel, Samuel Terrettaz, Christophe Danelon

Elsevier2008

Real-time high-sensitivity impedance measurement interface for tethered BLM biosensor arrays

Horst Vogel, Samuel Terrettaz, Yusuf Leblebici, Giovanni De Micheli, Luca Benini, Yüksel Temiz, Carlotta Guiducci

This paper presents a switched-capacitor (SC) current integrator circuit for impedance measurement of tethered bilayer lipid membrane (tBLM) biosensors. The circuit comprises a small number of high performance components enabling enhanced experimental flex ...

2008

Impedance spectroscopy of ion channels in tethered lipid bilayers

Horst Vogel, Samuel Terrettaz

A review. The efficient anal. of the function of ion channels is an important task in many different fields ranging from (bio)analytics and drug-screening to nanoelectronics. Here, the modulation of the channel activity of a synthetic ligand gated ion chan ...

2005

Investigating the function of ion channels in tethered lipid membranes by impedance spectroscopy

Horst Vogel, Samuel Terrettaz

A review. The function of biol. important ion channels can be measured in supported lipid membranes by impedance spectroscopy. This approach offers substantial advantages over traditional electrophysiol. measurements. In this article, we present an overvie ...

2005

Etude des propriétés électrochimiques et optiques de monocouches isolantes et de quelques processus de reconnaissance moléculaire induits a leur surface

Samuel Terrettaz

EPFL1993