Publications de Adrian Bachmann

Optical apparatus for dual beam heterodyne Fourier domain optical coherence tomography, has detector that synchronizes phase shift such that sample signal or sample interface moving at arbitrary velocity is detected by phase change

Adrian Bachmann, Theo Lasser, Roland Michaely, Martin Villiger, Rainer Leitgeb

NOVELTY - The apparatus has an optical unit for splitting a source field to produce and combine reference and biomedical sample light fields. An optical and electronic unit records a spectral interference pattern between combined light fields. A controlled ...

2008

Frequency encoded assessment of retinal physiology

Adrian Bachmann, Theo Lasser, Roland Michaely, Cédric Blatter, Rainer Leitgeb

We demonstrate in-vivo functional imaging of the human retina with Fourier domain optical coherence tomography employing frequency encoding of an excitation pattern. The principle is based on projecting a modulated rectangular pattern across the foveal reg ...

Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2008

Vectorial retinal blood flow and optical vessel vivisection for 3D angiography with high resolution resonant Doppler OCT

Adrian Bachmann, Theo Lasser, Roland Michaely, Martin Villiger, Cédric Blatter, Rainer Leitgeb

PURPOSE: To perform high speed and completely non-invasive 3D angiography at the optic nerve head region and to reconstruct vectorial 3D blood flow from optically segmented blood vessel structure as a pre-requisite for testing retinal function and physiolo ...

2007

Intensity based quantification of fast retinal blood flow in 3D via high resolution resonant Doppler spectral OCT

Adrian Bachmann, Theo Lasser, Roland Michaely, Martin Villiger, Cédric Blatter, Rainer Leitgeb

Resonant Doppler Fourier Domain Optical Coherence Tomography is a functional imaging modality for quantifying fast tissue flow. The method profits from the effect of interference fringe blurring in spectrometer-based FDOCT in the presence of sample motion. ...

Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2007

Vectorial reconstruction of retinal blood flow in three dimensions measured with high resolution resonant Doppler Fourier domain optical coherence tomography

Adrian Bachmann, Theo Lasser, Roland Michaely, Martin Villiger, Cédric Blatter, Rainer Leitgeb

Resonant Doppler Fourier domain optical coherence tomography (FDOCT) is a functional imaging tool for extracting tissue flow. The method is based on the effect of interference fringe blurring in spectrometer-based FDOCT, where the path difference between s ...

SPIE Society of Photo-optical Instrumentation Engineers2007

Resonant Doppler flow imaging and optical vivisection of retinal blood vessels

Adrian Bachmann, Theo Lasser, Martin Villiger, Cédric Blatter, Rainer Leitgeb

For Fourier domain optical coherence tomography any sample movement during camera integration causes blurring of interference fringes and as such reduction of sensitivity for flow detection. The proposed method overcomes this problem by phase-matching a re ...

2007

Dual-beam heterodyne Fourier domain optical coherence tomography

Adrian Bachmann, Theo Lasser, Roland Michaely, Rainer Leitgeb

We report on a novel method combining achromatic complex FDOCT signal reconstruction with a common path and dual beam configuration. The complex signal reconstruction allows resolving the complex ambiguity of the Fourier transform and to enhance the achiev ...

2007

Optical imaging apparatus for sample imaging method e.g. in-vivo measurement of full three-dimensional tissue volume has at least one detector that detects resulting spectral interference pattern at exit of interferometer

Adrian Bachmann, Theo Lasser, Lukas Steinmann, Martin Villiger, Rainer Leitgeb

The invention concerns an optical imaging apparatus comprising (o) a light source (1) , (p) sample holding means, (q) an interferometer, (r) reference means, (s) an objective (8) which is adapted to have its sample side focal plane crossing a sample held i ...

2007

Phase-locked Fourier domain optical coherence tomography

Adrian Bachmann

Fourier or spectral domain optical coherence tomography (FDOCT) is a multi-dimensional interferometric imaging modality that has attracted increasing interest during the last few years. The reason is its outstanding sensitivity allowing high speed 2D and 3 ...

EPFL2007

Heterodyne Fourier domain optical coherence tomography for full range probing with high axial resolution

Adrian Bachmann, Theo Lasser, Rainer Leitgeb

One of the main drawbacks of Fourier domain optical coherence tomography (FDOCT) is the limited measurement depth range. Phase shifting techniques allow reconstructing the complex sample signal resulting in a doubled depth range. In current complex FDOCT r ...

2006

Extended focus depth for Fourier domain optical coherence microscopy

Adrian Bachmann, Theo Lasser, Lukas Steinmann, Martin Villiger, Rainer Leitgeb

We report on a new detection scheme for Fourier domain optical coherence microscopy that exhibits high transverse resolution along an axially extended focal range. Nearly constant transverse resolution of ∼1.5 μm along a focal range of 200 μm is experiment ...

2006

Phase sensitive Fourier domain optical coherence tomography

Adrian Bachmann, Theo Lasser, Rainer Leitgeb

Optical Coherence Tomography (OCT) is an imaging technique with high axial resolution in the micro-meter-scale range combined with a high sensitivity allowing for example to probe weakly back-scattering structures beneath the surface of biological tissues ...

2006