Publications de Jonas Schenk | EPFL Graph Search

Influence of specific growth rate on specific productivity and glycosylation of a recombinant avidin produced by a Pichia pastoris Mut(+) strain

Ian William Marison, Urs von Stockar, Jonas Schenk, Carmen Jungo, Julien Urfer, Carole Wegmann, Krisztina Balàzs

A recombinant avidin-producing Mut(+) Pichia pastoris strain was used as a model organism to study the influence of the methanol feeding strategy on the specific product productivity (q(p)) and protein glycosylation. Fed-batch cultivations performed at var ...

2008

On-line monitoring of nine different batch cultures of E-coli by mid-infrared spectroscopy, using a single spectra library for calibration

Ian William Marison, Urs von Stockar, Jonas Schenk, Carla Viscasillas Nadal

A single spectra library was used to monitor on-line, by mid-infrared spectroscopy, nine different batch cultures of Escherichia coli performed with various medium compositions, including chemically complex formulations. Whereas the classic chemometrics ap ...

2008

pH prediction and control in bioprocesses using mid-infrared spectroscopy

Ian William Marison, Jonas Schenk

An on-line pH monitoring method based on mid-infrared spectroscopy relevant to bioprocesses is presented. This approach is non-invasive and does not require the addition of indicators or dyes, since it relies on the analysis of species of common buffers us ...

2008

A quantitative analysis of the benefits of mixed feeds of sorbitol and methanol for the production of recombinant avidin with Pichia pastoris

Ian William Marison, Urs von Stockar, Jonas Schenk, Carmen Jungo, Muriel Pasquier

2007

Simplified Fourier-transform mid-infrared spectroscopy calibration based on a spectra library for the on-line monitoring of bioprocesses

Ian William Marison, Urs von Stockar, Jonas Schenk

2007

Simplified approaches to mid-infrared spectrometers calibration for bioprocess monitoring applications

Jonas Schenk

This thesis aimed at developing new, simple methods of calibration for on-line monitoring of bioprocesses by Fourier-transform mid-infrared spectroscopy (FTIR). The conventional calibration approach implies the preparation and measurement of a large number ...

EPFL2007

A simple method to monitor and control methanol feeding of Pichia pastoris fermentations using mid-IR spectroscopy

Ian William Marison, Urs von Stockar, Jonas Schenk

2007