Publications de Lionel Ambroise Micol

In-vivo performance of high-density collagen gel tubes for urethral regeneration in a rabbit model

Lionel Ambroise Micol, Jeffrey Alan Hubbell, Peter Frey

Congenital malformations or injuries of the urethra can be treated using existing autologous tissue, but these procedures are sometimes associated with severe complications. Therefore, tissue engineering may be advantageous for generating urethral grafts. ...

Elsevier2012

Hydrogels for Urinary Tract Tissue Engineering

Lionel Ambroise Micol

Several urinary tract disorders, such as hypospadias or bladder cancer, require reconstructive surgery to preserve the patient's quality of life and at times even save their life. The current available surgical treatments, involving grafts from other tissu ...

EPFL2011

A collagen-poly(lactic acid-co-epsilon-caprolactone) hybrid scaffold for bladder tissue regeneration

Florian Maria Wurm, Lionel Ambroise Micol, Jeffrey Alan Hubbell, Peter Frey

Scaffold materials should favor cell attachment and proliferation, and provide designable 3D structures with appropriate mechanical strength. Collagen matrices have proven to be beneficial scaffolds for tissue regeneration. However, apart from small intest ...

2011

High-density collagen gel tubes as a matrix for primary human bladder smooth muscle cells

Lionel Ambroise Micol, Jeffrey Alan Hubbell, Peter Frey

Tissue-engineered grafts for the urinary tract are being investigated for the potential treatment of several urologic diseases. These grafts, predominantly tubular-shaped, usually require in vitro culture prior to implantation to allow cell engraftment on ...

Elsevier2011

In vivo study of an injectable poly(acrylonitrile)-based hydrogel paste as a bulking agent for the treatment of urinary incontinence

Lionel Ambroise Micol, Jeffrey Alan Hubbell, Peter Frey

Urinary incontinence can be treated by endoscopic injection of bulking agents, however, no optimal therapeutic effect has been achieved upon this treatment yet. In the present study, the development of a injectable poly(acrylonitrile) hydrogel paste is des ...

Elsevier2010

Novel cell-seeded, tubular-shaped and highly dense collagen gel for tissue engineering

Lionel Ambroise Micol, Jeffrey Alan Hubbell, Peter Frey

2008