Publications de Stephanie Clarke

Emotional sounds in space: asymmetrical representation within early-stage auditory areas

Evidence from behavioral studies suggests that the spatial origin of sounds may influence the perception of emotional valence. Using 7T fMRI we have investigated the impact of the categories of sound (vocalizations; non-vocalizations), emotional valence (p ...

FRONTIERS MEDIA SA2023

A brief exposure to rightward prismatic adaptation changes resting-state network characteristics of the ventral attentional system

Patric Hagmann, Stephanie Clarke

A brief session of rightward prismatic adaptation (R-PA) has been shown to alleviate neglect symptoms in patients with right hemispheric damage, very likely by switching hemispheric dominance of the ventral attentional network (VAN) from the right to the l ...

2020

Processing pathways for emotional vocalizations

Stephanie Clarke, Olivier Benoit Thomas Reynaud

Emotional sounds are processed within a large cortico-subcortical network, of which the auditory cortex, the voice area, and the amygdala are the core regions. Using 7T fMRI, we have compared the effect of emotional valence (positive, neutral, and negative ...

2019

Keeping track of sound objects in space: The contribution of early-stage auditory areas

Stephanie Clarke

The influential dual-stream model of auditory processing stipulates that information pertaining to the meaning and to the position of a given sound object is processed in parallel along two distinct pathways, the ventral and dorsal auditory streams. Functi ...

2018

Electrically Assisted Movement Therapy in Chronic Stroke Patients With Severe Upper Limb Paresis: A Pilot, Single-Blind, Randomized Crossover Study

Stephanie Clarke, José del Rocio Millán Ruiz, Silvio Ionta, Andrea Maesani, Andrea Biasiucci

Objective To evaluate the effects of electrically assisted movement therapy (EAMT) in which patients use functional electrical stimulation, modulated by a custom device controlled through the patient's unaffected hand, to produce or assist task-specific up ...

Elsevier2017

High-Resolution fMRI of Auditory Cortical Map Changes in Unilateral Hearing Loss and Tinnitus

Stephanie Clarke, Dimitri Nestor Alice Van De Ville, Wietske Van der Zwaag, Naghmeh Ghazaleh, Melissa Saenz

Animal models of hearing loss and tinnitus observe pathological neural activity in the tonotopic frequency maps of the primary auditory cortex. Here, we applied ultra high-field fMRI at 7 T to test whether human patients with unilateral hearing loss and ti ...

Springer Verlag2017

Intrahemispheric cortico-cortical connections of the human auditory cortex

Jean-Philippe Thiran, Patric Hagmann, Stephanie Clarke, Reto Meuli, Alessandra Griffa, Leila Cammoun

The human auditory cortex comprises the supratemporal plane and large parts of the temporal and parietal convexities. We have investigated the relevant intrahemispheric cortico-cortical connections using in vivo DSI tractography combined with landmark-base ...

Springer Heidelberg2015

Representation of Sound Objects within Early-Stage Auditory Areas: A Repetition Effect Study Using 7T fMRI

Stephanie Clarke, Wietske Van der Zwaag, Melissa Saenz

Environmental sounds are highly complex stimuli whose recognition depends on the interaction of top-down and bottom-up processes in the brain. Their semantic representations were shown to yield repetition suppression effects, i. e. a decrease in activity d ...

Public Library of Science2015

Tonotopic Gradients in Human Primary Auditory Cortex: Concurring Evidence From High-Resolution 7 T and 3 T fMRI

Stephanie Clarke, Wietske Van der Zwaag, Melissa Saenz

The tonotopic representations within the primary auditory cortex (PAC) have been successfully mapped with ultra-high field fMRI. Here, we compared the reliability of this tonotopic mapping paradigm at 7 T with 1.5 mm spatial resolution with maps acquired a ...

Springer2015

Tuning In to Sound: Frequency-Selective Attentional Filter in Human Primary Auditory Cortex

Stephanie Clarke, Wietske Van der Zwaag, Melissa Saenz

Cocktail parties, busy streets, and other noisy environments pose a difficult challenge to the auditory system: how to focus attention on selected sounds while ignoring others? Neurons of primary auditory cortex, many of which are sharply tuned to sound fr ...

Society for Neuroscience2013

Human Primary Auditory Cortex Follows the Shape of Heschl's Gyrus

Stephanie Clarke, Wietske Van der Zwaag, José Pedro Rebelo Ferreira Marques, Melissa Saenz

The primary auditory cortex (PAC) is central to human auditory abilities, yet its location in the brain remains unclear. We measured the two largest tonotopic subfields of PAC (hA1 and hR) using high-resolution functional MRI at 7 T relative to the underly ...

Society for Neuroscience2011

Where sound position influences sound object representations: A 7-T fMRI study

Stephanie Clarke, Rolf Gruetter, Wietske Van der Zwaag

Evidence from human and non-human primate studies supports a dual-pathway model of audition, with partially segregated cortical networks for sound recognition and sound localisation, referred to as the What and Where processing streams. In normal subjects, ...

Elsevier2010

Clarke Spatial modulation of sound object representations

Stephanie Clarke, Rolf Gruetter, Wietske Van der Zwaag

2009

Distribution of the monocarboxylate transporter MCT2 in human cerebral cortex: an immunohistochemical study

Pierre Magistretti, Stephanie Clarke, Luc Pellerin

The monocarboxylate transporter MCT2 belongs to a large family of membrane proteins involved in the transport of lactate, pyruvate and ketone bodies. Although its expression in rodent brain has been well documented, the presence of MCT2 in the human brain ...

2008

Expression of the monocarboxylate transporter MCT1 in the adult human brain cortex

Pierre Magistretti, Stephanie Clarke, Luc Pellerin

Distribution of the monocarboxylate transporter MCT1 has been investigated in the cortex of normal adult human brain. Similarly to the glucose transporter GLUT1 55 kDa isoform, MCT1 was found to be strongly expressed on blood vessels in all cortical layers ...

2006