Publications de Sabrina Laus | EPFL Graph Search

Time-resolved measurement of rat brain glycogen absolute concentration in vivo

Sabrina Laus, Rolf Gruetter, Ruud van Heeswijk, Lijing Xin, Hanne Frenkel, Hongxia Lei

Wiley-Blackwell2009

Non-invasive quantification of brain glycogen absolute concentration

Sabrina Laus, Rolf Gruetter, Ruud van Heeswijk, Lijing Xin, Hanne Frenkel, Hongxia Lei

The only currently available method to measure brain glycogen in vivo is C-13 NMR spectroscopy. Incorporation of C-13-labeled glucose (Glc) is necessary to allow glycogen measurement, but might be affected by turnover changes. Our aim was to measure glycog ...

Wiley-Blackwell2008

Gadonanotubes as Ultrasensitive pH-Smart Probes for Magnetic Resonance Imaging

André Merbach, Lothar Helm, Eva Jakab Toth, Sabrina Laus

With their nanoscalar, superparamagnetic Gd3+-ion clusters (1 ´ 5 nm) confined within ultrashort (20-80 nm) single- walled carbon nanotube capsules, gadonanotubes are high- performance T1-weighted contrast agents for magnetic resonance imaging (MRI). At 1. ...

American Chemical Society (ACS)2008

Relaxivity of Gd-based contrast agents on X nuclei with long intrinsic relaxation times in aqueous solutions

Sabrina Laus, Rolf Gruetter, Ruud van Heeswijk

The relaxivity of commercially available gadolinium (Gd)-based contrast agents was studied for X-nuclei resonances with long intrinsic relaxation times ranging from 6 s to several hundred seconds. Omniscan in pure 13C formic acid had a relaxivity of 2.9 mM ...

Elsevier2007

Multiple-frequency EPR spectra of two aqueous Gd3+ polyaminopolypyridinecarboxylate complexes: a study of high field effects

Lothar Helm, Alain Borel, Sabrina Laus, Marinella Mazzanti

In the search for highly efficient magnetic resonance imaging contrast agents, polyaminopolypyridinecarboxylate complexes of Gd3+ have shown unusual properties with both very rapid and very slow electron spin relaxation in solution observed by electron par ...

2007

Understanding Paramagnetic Relaxation Phenomena for Water-Soluble Gadofullerenes

André Merbach, Lothar Helm, Eva Jakab Toth, Sabrina Laus

2007

Rotational Dynamics Account for pH-Dependent Relaxivities of PAMAM Dendrimeric, Gd-Based Potential MRI Contrast Agents

André Merbach, Eva Jakab Toth, Sabrina Laus

The EPTPA5- chelate, which ensures fast water exchange in GdIII complexes, has been coupled to three different generations (5, 7, and 9) of polyamidoamine (PAMAM) dendrimers through benzylthiourea linkages (H5EPTPA=ethylenepropylenetriamine-N,N,N,N,N-penta ...

2005

New strategies for highly efficient medical MRI contrast agents : Gd(III) poly(amino carboxylates) with fast water exchange and Gd(III) trapped in carbon cages

Sabrina Laus

During the last two decades, magnetic resonance imaging (MRI) has evolved into one of the most powerful techniques in medical diagnosis. Among the various medical diagnostic modalities, such as X-ray or ultra-sound imaging, MRI is the technique of choice e ...

EPFL2005

Destroying gadofullerene aggregates by salt addition in aqueous solution of Gd@C60(OH)x and Gd@C60[C(COOH2)]10

André Merbach, Lothar Helm, Eva Jakab Toth, Sabrina Laus

2005

Superparamagnetic gadonanotubes are high-performance MRI contrast agents

André Merbach, Lothar Helm, Eva Jakab Toth, Sabrina Laus

Royal Society of Chemistry2005