Publications de Laurent Renaud Uldry

Systematic comparison of non-invasive measures for the assessment of atrial fibrillation complexity: a step forward towards standardization of atrial fibrillation electrogram analysis

Jean-Marc Vesin, Laurent Renaud Uldry, Jérôme Sébastien Van Zaen

Aims To present a comparison of electrocardiogram-based non-invasive measures of atrial fibrillation (AF) substrate complexity computed on invasive animal recordings to discriminate between short-term and long-term AF. The final objective is the selection ...

Oxford Univ Press2015

Atrial septal pacing for the termination of atrial fibrillation: study in a biophysical model of human atria

Jean-Marc Vesin, Lukas Kappenberger, Laurent Renaud Uldry

Aims While successful termination by pacing of organized atrial tachycardias has been observed in patients, single site rapid pacing has not yet led to conclusive results for the termination of atrial fibrillation (AF). The purpose of this study was to eva ...

Oxford Univ Press2012

Measures of spatiotemporal organization differentiate persistent from long-standing atrial fibrillation

Jean-Marc Vesin, Yann Prudat, Lukas Kappenberger, Laurent Renaud Uldry, Jérôme Sébastien Van Zaen

This study presents an automatic diagnostic method for the discrimination between persistent and long-standing atrial fibrillation (AF) based on the surface electrocardiogram (ECG). Standard 12-lead ECG recordings were acquired in 53 patients with either p ...

Oxford Univ Press2012

Estimating the time scale and anatomical location of atrial fibrillation spontaneous termination in a biophysical model

Vincent Jacquemet, Jean-Marc Vesin, Lukas Kappenberger, Laurent Renaud Uldry

Due to their transient nature, spontaneous terminations of atrial fibrillation (AF) are difficult to investigate. Apparently, confounding experimental findings about the time scale of this phenomenon have been reported, with values ranging from 1 s to 1 mi ...

Springer-Verlag2012

Harmonic frequency tracking algorithm for predicting the success of pharmacological cardioversion of atrial fibrillation

Jean-Marc Vesin, Andréa Buttu, Lukas Kappenberger, Laurent Renaud Uldry, Jérôme Sébastien Van Zaen

Purpose: Non-invasively predicting the success of pharmacological cardioversion for patients with atrial fibrillation (AF) would be of great interest in clinical settings. In this study, an adaptive algorithm for tracking fundamental and harmonic component ...

2011

Therapeutic Strategies for the Treatment of Atrial Fibrillation : New Insights from Biophysical Modeling and Signal Processing

Laurent Renaud Uldry

Atrial fibrillation is the most common cardiac rhythm disorder encountered in clinical practice, often leading to severe complications such as heart failure and stroke. This arrhythmia, increasing in prevalence with age, already affects several millions of ...

EPFL2011

Early temporal and spatial regularization of persistent atrial fibrillation predicts termination and arrhythmia-free outcome

Laurent Renaud Uldry

BACKGROUND Termination of persistent atrial fibrillation (AF) is a valuable ablation endpoint but is difficult to anticipate. We evaluated whether temporal and spatial indices of AF regularization predict intraprocedural AF termination and outcome. ...

2011

Study of the effect of rapid pacing of atrial fibrillation on the non-paced atrium

Jean-Marc Vesin, Lukas Kappenberger, Laurent Renaud Uldry

Purpose: Experimental studies showed that local capture of atrial fibrillation (AF) by rapid pacing was possible in humans. However, contradictory observations were reported on its effect at distant atrial sites. The present model-based study investigated ...

2011

Novel complexity measurements in the ECG differentiate persistent from permanent atrial fibrillation

Jean-Marc Vesin, Lukas Kappenberger, Laurent Renaud Uldry, Jérôme Sébastien Van Zaen

Purpose: Distinguishing persistent from permanent atrial fibrillation (AF) in a reliable way would improve AF patient management, as cardioversion options could be considered appropriately. In this study, complexity measures based on the combined analysis ...

2011

Influence of pacing site on the spatial extent of capture during atrial fibrillation rapid pacing

Jean-Marc Vesin, Laurent Renaud Uldry

2010

Early spatial and temporal organization during atrial fibrillation ablation predicts arrhythmia termination

Arvind Shah, Laurent Renaud Uldry

2010

Estimation of tissue wavelength predicts the feasibility of local capture by rapid pacing in atrial fibrillation

Jean-Marc Vesin, Laurent Renaud Uldry

2010

Optimizing Local Capture of Atrial Fibrillation by Rapid Pacing: Study of the Influence of Tissue Dynamics

Vincent Jacquemet, Jean-Marc Vesin, Lukas Kappenberger, Laurent Renaud Uldry

While successful termination by pacing of organized atrial tachycardias has been observed in patients, rapid pacing of AF can induce a local capture of the atrial tissue but in general no termination. The purpose of this study was to perform a systematic e ...

Springer Verlag2010

Temporal and spatial regularization of persistent atrial fibrillation is associated with arrhythmia free outcome

Arvind Shah, Laurent Renaud Uldry

2010

Early temporal and spatial regularization during ablation of persistent atrial fibrillation predicts arrhythmia termination

Arvind Shah, Laurent Renaud Uldry

2010

Adaptive tracking of EEG oscillations

Jean-Marc Vesin, Yann Prudat, Laurent Renaud Uldry, Jérôme Sébastien Van Zaen, Cédric Duchene

Neuronal oscillations are an important aspect of EEG recordings. These oscillations are supposed to be involved in several cognitive mechanisms. For instance, oscillatory activity is considered a key component for the top-down control of perception. Howeve ...

2010

Effect of atrial fibrillation dynamics on the mechanisms of spontaneous termination

Jean-Marc Vesin, Laurent Renaud Uldry

2010

Optimization of antitachycardia pacing protocols applied to atrial fibrillation: insights from a biophysical model

Jean-Marc Vesin, Lukas Kappenberger, Laurent Renaud Uldry

We present a model-based systematic study of antitachycardia pacing protocols applied to atrial fibrillation, focusing on the ability to achieve and maintain capture during pacing, as a function of both pacing site and period. We observed that pacing sites ...

Ieee Service Center, 445 Hoes Lane, Po Box 1331, Piscataway, Nj 08855-1331 Usa2009

The effect of pacing site and frequency on capture of atrial fibrillation observed in a biophysical model

Jean-Marc Vesin, Lukas Kappenberger, Laurent Renaud Uldry

2009

The Role of Atrial Modeling in the Development of ECG Processing Tools

Vincent Jacquemet, Jean-Marc Vesin, Lukas Kappenberger, Mathieu Lemay, Laurent Renaud Uldry, Cédric Duchene

The standard ECG remains the most common non-invasive tool for assessing atrial fibrillation. Specific signal processing techniques have been developed to improve the diagnosis. However, validation of such tools is challenging and comprehensive invasive da ...

2009