Publications de Andreas Schmocker

Pulsatile Flow-Induced Fatigue-Resistant Photopolymerizable Hydrogels for the Treatment of Intracranial Aneurysms

Dominique Pioletti, Andreas Schmocker, Lucio Feo Pancaldi-Giubbini, Christophe Moser, Mahmut Selman Sakar, Oriane Poupart

An alternative intracranial aneurysm embolic agent is emerging in the form of hydrogels due to their ability to be injected in liquid phase and solidify in situ. Hydrogels have the ability to fill an aneurysm sac more completely compared to solid implants ...

2021

In vitro Implementation of Photopolymerizable Hydrogels as a Potential Treatment of Intracranial Aneurysms

Dominique Pioletti, Andreas Schmocker, Christophe Moser, Oriane Poupart

Intracranial aneurysms are increasingly being treated with endovascular therapy, namely coil embolization. Despite being minimally invasive, partial occlusion and recurrence are more frequent compared to open surgical clipping. Therefore, an alternative tr ...

2020

Composite Double-Network Hydrogels To Improve Adhesion on Biological Surfaces

Dominique Pioletti, Pierre-Etienne Bourban, Andreas Schmocker, Azadeh Khoushabi, Christophe Moser, Céline Samira Wyss, Martin Broome, Peyman Karami

Despite the development of hydrogels with high mechanical properties, insufficient adhesion between these materials and biological surfaces significantly limits their use in the biomedical field. By controlling toughening processes, we designed a composite ...

2018

Curable filler material for tubular structures

Andreas Schmocker

A radiopaque composition with low viscosity and increased photopolymerizability for application or filling of hollow structures is disclosed. Moreover, a method to apply and monitor the application and/or the photopolymerization of the composition are pres ...

2018

Photopolymerizable bone filler material

Dominique Pioletti, Andreas Schmocker, Oriane Poupart

A photopolymerizable bone filler material comprising a fluid polymeric material, a photoinitiator and a plurality of solid, polymeric optical fibers is disclosed, wherein said optical fibers are used for both illumination and reinforcement of the entire ph ...

2018

A photopolymerized composite hydrogel and surgical implanting tool for a nucleus pulposus replacement

Dominique Pioletti, Pierre-Etienne Bourban, Andreas Schmocker, Azadeh Khoushabi, Christophe Moser

Nucleus pulposus replacements have been subjected to highly controversial discussions over the last 40 years. Their use has not yet resulted in a positive outcome to treat herniated disc or degenerated disc disease. The main reason is that not a single imp ...

Elsevier2016

Surgical probe and implant development for nucleus pulposus replacements

Andreas Schmocker

Intervertebral disc degeneration is a major reason why we experience low back pain. Intervertebral discs are located in-between the vertebrae of the spine. They act, among other, as shock absorbers by distributing the mechanical load applied to the spine w ...

EPFL2016

In-situ photopolymerized and monitored implants: successful application to an intervertebral disc replacement

Dominique Pioletti, Andreas Schmocker, Azadeh Khoushabi, Christophe Moser

Photopolymerization is a common method to harden materials initially in a liquid state. A surgeon can directly trigger the solidification of a dental implant or a bone or tissue filler by using ultra-violet light. Traditionally, photopolymerization has bee ...

Spie-Int Soc Optical Engineering2016

Device and method for injection, photoactivation and solidifaction of liquid embolic material in the vascular system or other organic cavities

Andreas Schmocker, Christophe Moser

The present invention concerns an organic cavity injection device including an injection cannula for injecting a photo-activatable substance inside an organic cavity; at least one element or a plurality of elements configured to control the removal of a re ...

2016

Device for photoactivation and reaction monitoring

Dominique Pioletti, Pierre-Etienne Bourban, Andreas Schmocker, Christophe Moser

The present invention relates to a device to photocure and/or photoactivate a photosensitive material. The device comprises several subsystems to transmit light towards an area of interest where a photosensitive material is applied as well as to collect li ...

2016

Miniature probe for the delivery and monitoring of a photopolymerizable material

Dominique Pioletti, Pierre-Etienne Bourban, Andreas Schmocker, Azadeh Khoushabi, Christophe Moser

Photopolymerization is a common method to cure materials initially in a liquid state, such as dental implants or bone or tissue fillers. Recent advances in the development of biocompatible gel- and cement-systems open up an avenue for in situ photopolymeri ...

SPIE Society of Photo-optical Instrumentation Engineers2015

Photo-polymerization, swelling and mechanical properties of cellulose fibre reinforced poly(ethylene glycol) hydrogels

Dominique Pioletti, Pierre-Etienne Bourban, Andreas Schmocker, Azadeh Khoushabi

The application of hydrogels as load-bearing biomedical components is often limited by their mechanical properties. Often an attempt to improve a hydrogel's stiffness is accompanied by a loss of toughness and swelling properties. In this work, we show that ...

Elsevier Sci Ltd2015

Development of an in situ controllable polymerization tool and process for hydrogel used to replace nucleus pulposus

Dominique Pioletti, Pierre-Etienne Bourban, Andreas Schmocker, Azadeh Khoushabi, Christophe Moser

Currently implants or tissue replacements are inserted either as a whole implant or by injecting a liquid which polymerizes to form a solid implant at the appropriate location. This is either highly invasive or not controllable. We developed a tool to perf ...

Spie-Int Soc Optical Engineering2015

Photopolymerization device for minimally invasive implants: application to nucleus pulposus replacement

Dominique Pioletti, Pierre-Etienne Bourban, Andreas Schmocker, Azadeh Khoushabi, Christophe Moser

Photopolymerization is a common tool to harden materials initially in a liquid state. A surgeon can directly trigger the solidification of a dental implant or a bone or tissue filler. Traditionally, photopolymerization has been used mainly in dentistry. Ov ...

Springer2015

In-situ photopolymerization and monitoring device for controlled shaping of tissue fillers, replacements or implants

Dominique Pioletti, Andreas Schmocker, Azadeh Khoushabi, Christophe Moser

Photopolymerization is a common tool to harden materials initially in a liquid state. A surgeon can directly trigger the solidification of a dental implant or a bone or tissue filler simply by illumination. Traditionally, photopolymerization has been used ...

Spie-Int Soc Optical Engineering2015

Minimally Invasive Photopolymerization In Intervertebral Disc Tissue Cavities

Dominique Pioletti, Pierre-Etienne Bourban, Andreas Schmocker, Azadeh Khoushabi, Christophe Moser

Photopolymerized hydrogels are commonly used for a broad range of biomedical applications. As long as the polymer volume is accessible, gels can easily be hardened using light illumination. However, in clinics, especially for minimally invasive surgery, it ...

Spie-Int Soc Optical Engineering2014

Mechanical Properties Of A Photopolymerizable Hydrogel For Intervertebral Disc Replacement

Dominique Pioletti, Pierre-Etienne Bourban, Andreas Schmocker, Azadeh Khoushabi

We report on the modelling and experimental validation of a photopolymerizable hydrogel for a Nucleus Pulposus replacement. ...

De Gruyter2013

Multi-Scale Modeling Of Photopolymerization For Medical Hydrogel-Implant Design

Dominique Pioletti, Pierre-Etienne Bourban, Andreas Schmocker, Azadeh Khoushabi, Salma Farahi

We report on the modeling of a photopolymerizable hydrogel and its application as a replacement of the interior of the intervertebral disc (so called Nucleus Pulposus). The hydrogel is initially injected in its liquid form and then photopolymerized via a s ...

Spie-Int Soc Optical Engineering2013