Publications de Samuel Kilchenmann

On‐chip technology for single‐cell arraying, electrorotation‐based analysis and selective release

Samuel Kilchenmann, Carlotta Guiducci, Kevin Keim, Paul Karoly Otto Ery, Mohamed Zakarya Alsaid Ali Rashed

This paper reports a method for label-free single-cell biophysical analysis of multiple cells trapped in suspension by electrokinetic forces. Tri-dimensional pillar electrodes arranged along the width of a microfluidic chamber define actuators for single c ...

2019

Microfluidic and Electrokinetic Manipulation of Single Cells

Samuel Kilchenmann

Traditional cell assays report on the average results of a cell population. However, a wide range of new tools are being developed for a fundamental understanding of single cell's functionality. Nonetheless, the current tools are either limited in their th ...

EPFL2017

Metal-Coated SU-8 Structures for High-Density 3-D Microelectrode Arrays

Samuel Kilchenmann, Carlotta Guiducci, Pietro Maoddi, Enrica Rollo

Electric fields can be effectively used to sense, manipulate, and move particles in lab-on-a-chip devices. Nevertheless, the throughput of such devices is a critical issue, which can be effectively improved by increasing the height of the microchannels. Fo ...

Institute of Electrical and Electronics Engineers2016

Metal-coated silicon micropillars for freestanding 3D-electrode arrays in microchannels

Samuel Kilchenmann, Carlotta Guiducci, Elena Bianchi, Enrica Rollo

This paper presents a fabrication process for arrays of high-aspect-ratio micropillar electrodes, which are freestanding 3D structures that feature metal sidewalls connected to passivated planar wires. Facing vertical electrodes are considered to be a key ...

Elsevier2013

Detecting particles flowing through interdigitated 3D microelectrodes

Samuel Kilchenmann, Enrico Accastelli, Carlotta Guiducci, Elena Bianchi, Enrica Rollo

Counting cells in a large microchannel remains challenging and is particularly critical for in vitro assays, such as cell adhesion assays. This paper addresses this issue, by presenting the development of interdigitated three-dimensional electrodes, which ...

Ieee2012

3D Integration Technology for Lab-on-a-Chip Applications

Yusuf Leblebici, Samuel Kilchenmann, Yüksel Temiz, Carlotta Guiducci

A review is presented of advances and challenges in fully integrated systems for personalised medicine applications. One key issue for the commercialisation of such systems is the disposability of the assay-substrate at a low cost. This work adds a new dim ...

Institution of Engineering and Technology2011