Publications de Stephan Rauschenbach

Visualizing Chiral Interactions in Carbohydrates Adsorbed on Au(111) by High-Resolution STM Imaging

Klaus Kern, Stephan Rauschenbach, Uta Schlickum

Carbohydrates are the most abundant organic material on Earth and the structural "material of choice" in many living systems. Nevertheless, design and engineering of synthetic carbohydrate materials presently lag behind that for protein and nucleic acids. ...

Wiley-VCH Verlag GmbH2023

Direct observation of glycans bonded to proteins and lipids at the single-molecule level

Klaus Kern, Stephan Rauschenbach

Proteins and lipids decorated with glycans are found throughout biological entities, playing roles in biological functions and dysfunctions. Current analytical strategies for these glycan-decorated biomolecules, termed glycoconjugates, rely on ensemble-ave ...

American Association for the Advancement of Science2023

Molecular sensitised probe for amino acid recognition within peptide sequences

Klaus Kern, Stephan Rauschenbach, Uta Schlickum, Daniel Pablo Rosenblatt, Sabine Abb, Sebastian Koslowski

The combination of low-temperature scanning tunnelling microscopy with a mass-selective electro-spray ion-beam deposition established the investigation of large biomolecules at nanometer and sub-nanometer scale. Due to complex architecture and conformation ...

Nature Portfolio2023

Phase Reconstruction of Low-Energy Electron Holograms of Individual Proteins

Klaus Kern, Stephan Rauschenbach, Sven Alexander Szilagyi, Hannah Julia Ochner

Low-energy electron holography (LEEH) is one of the few techniques capable of imaging large and complex three-dimensional molecules, such as proteins, on the single molecule level at subnanometer resolution. During the imaging process, the structural infor ...

AMER CHEMICAL SOC2022

Landing Proteins on Graphene Trampoline Preserves Their Gas-Phase Folding on the Surface

Klaus Kern, Stephan Rauschenbach, Sven Alexander Szilagyi, Hannah Julia Ochner

Molecule-surface collisions are known to initiate dynamics that lead to products inaccessible by thermal chemistry. These collision dynamics, however, have mostly been examined on bulk surfaces, leaving vast opportunities unexplored for molecular collision ...

AMER CHEMICAL SOC2023

Catalyzing Bond-Dissociation in Graphene via Alkali-Iodide Molecules

Klaus Kern, Stephan Rauschenbach, Sabine Abb, Sven Alexander Szilagyi, Hannah Julia Ochner

Atomic design of a 2D-material such as graphene can be substantially influenced by etching, deliberately induced in a transmission electron microscope. It is achieved primarily by overcoming the threshold energy for defect formation by controlling the kine ...

WILEY-V C H VERLAG GMBH2021

Low-energy electron holography imaging of conformational variability of single-antibody molecules from electrospray ion beam deposition

Klaus Kern, Stephan Rauschenbach, Sabine Abb, Sven Alexander Szilagyi, Hannah Julia Ochner

Imaging of proteins at the single-molecule level can reveal conformational variability, which is essential for the understanding of biomolecules. To this end, a biologically relevant state of the sample must be retained during both sample preparation and i ...

National Academy of Sciences2021

Identifying the origin of local flexibility in a carbohydrate polymer

Klaus Kern, Stephan Rauschenbach, Sabine Abb

Correlating the structures and properties of a polymer to its monomer sequence is key to understanding how its higher hierarchy structures are formed and how its macroscopic material properties emerge. Carbohydrate polymers, such as cellulose and chitin, a ...

National Academy of Sciences2021

Exploring the Molecular Conformation Space by Soft Molecule- Surface Collision

Klaus Kern, Stephan Rauschenbach, Sabine Abb

Biomolecules function by adopting multiple conformations. Such dynamics are governed by the conformation landscape whose study requires characterization of the ground and excited conformation states. Here, the conformational landscape of a molecule is samp ...

AMER CHEMICAL SOC2020

Carbohydrate Self-Assembly at Surfaces: STM Imaging of Sucrose Conformation and Ordering on Cu(100)

Klaus Kern, Stephan Rauschenbach, Sabine Abb

Saccharides are ubiquitous biomolecules, but little is known about their interaction with, and assembly at, surfaces. By combining preparative mass spectrometry with scanning tunneling microscopy, we have been able to address the conformation and self-asse ...

Wiley-VCH Verlag GmbH2019

Chemical Analysis of Complex Surface-Adsorbed Molecules and Their Reactions by Means of Cluster-Induced Desorption/lonization Mass Spectrometry

Klaus Kern, Stephan Rauschenbach, Gordon Rinke, Sabine Abb

2018

Electron microscopy of polyoxometalate ions on graphene by electrospray ion beam deposition

Klaus Kern, Stephan Rauschenbach, Marko Burghard, Sabine Abb

2018

Two-dimensional honeycomb network through sequence-controlled self-assembly of oligopeptides

Klaus Kern, Stephan Rauschenbach, Sabine Abb

The sequence of a peptide programs its self-assembly and hence the expression of specific properties through non-covalent interactions. A large variety of peptide nanostructures has been designed employing different aspects of these non-covalent interactio ...

Nature Publishing Group2016

The classical and quantum dynamics of molecular spins on graphene

Klaus Kern, Stephan Rauschenbach, Marko Burghard

Controlling the dynamics of spins on surfaces is pivotal to the design of spintronic(1) and quantum computing(2) devices. Proposed schemes involve the interaction of spins with graphene to enable surface-state spintronics(3,4) and electrical spin manipulat ...

Nature Publishing Group2016

Soft-landing electrospray ion beam deposition of sensitive oligoynes on surfaces in vacuum

Klaus Kern, Stephan Rauschenbach, Holger Frauenrath, Stephen Schrettl, Tobias Hoheisel, Gordon Rinke

Characterizing the complex structure of such molecules with highly resolving, vacuum-based methods like scanning probe microscopy requires their transfer into the gas phase and further onto an atomically clean surface in ultrahigh vacuum without causing ad ...

Elsevier2015

Self-assembly of bis(phthalocyaninato) terbium on metal surfaces

Klaus Kern, Sebastian Stepanow, Stephan Rauschenbach

Single-molecule magnets represent the smallest stable magnetic entities available to technology, with promising applications in data storage and quantum computation in sight. Therefore, an interface between devices and single-molecule magnets must be devel ...

Iop Publishing Ltd2015

Bottom up fabrication of (9,0) zigzag and (6,6) armchair carbon nanotube end-caps on the Rh(111) surface

Klaus Kern, Stephan Rauschenbach, Nasiba Abdurakhmanova

The exploration and wide application of single walled carbon nanotubes (SWCNTs) require the development of new synthetic approaches enabling facile and fully rational CNT fabrication. In this communication the conversion of two precursors yielding the pote ...

Pergamon-Elsevier Science Ltd2015

Active Conformation Control of Unfolded Proteins by Hyperthermal Collision with a Metal Surface

Klaus Kern, Stephan Rauschenbach, Gordon Rinke

The physical and chemical properties of macromolecules like proteins are strongly dependent on their conformation. The degrees of freedom of their chemical bonds generate a huge conformational space, of which, however, only a small fraction is accessible i ...

Amer Chemical Soc2014

A hydrodynamically optimized nano-electrospray ionization source and vacuum interface

Klaus Kern, Stephan Rauschenbach, Mark Pauly, Gordon Rinke

The coupling of atmospheric pressure ionization (API) sources like electrospray ionization (ESI) to vacuum based applications like mass spectrometry (MS) or ion beam deposition (IBD) is done by differential pumping, starting with a capillary or pinhole inl ...

Royal Soc Chemistry2014

Atomic-Scale Observation of Multiconformational Binding and Energy Level Alignment of Ruthenium-Based Photosensitizers on TiO2 Anatase

Klaus Kern, Feliciano Giustino, Sebastian Stepanow, Stephan Rauschenbach, Christopher Seiji Kley, Gordon Rinke, Christian Alexander Stephan Dette

Dye-sensitized solar cells constitute a promising approach to sustainable and low-cost solar energy conversion. Their overall efficiency crucially depends on the effective coupling of the photosensitizers to the photoelectrode and the details of the dye's ...

Amer Chemical Soc2014