Publications de Hanne Frenkel | EPFL Graph Search

Characterization of sustained BOLD activation in the rat barrel cortex and Neurochemical consequences

Rolf Gruetter, Lijing Xin, Hanne Frenkel, Nathalie Just

To date, only a couple of functional MR spectroscopy (fMRS) studies were conducted in rats. Due to the low temporal resolution of 1H-MRS techniques, prolonged stimulation paradigms are necessary for investigating the metabolic outcome in the rat brain duri ...

Elsevier2013

In vivo Magnetic Resonance Spectroscopy (MRS) studies of brain metabolism during ammonia infusion

Bernard Lanz, Rolf Gruetter, Hanne Frenkel, Cristina Ramona Cudalbu

2010

Imaging glutamine synthesis rates in the hyperammonemic rat brain

Bernard Lanz, Rolf Gruetter, Hanne Frenkel, Cristina Ramona Cudalbu

2010

Investigation of spatial distribution of metabolites in rat brain at elevated plasma glucose levels

Rolf Gruetter, Hanne Frenkel, Cristina Ramona Cudalbu

2010

Alteration of brain glycogen turnover in the conscious rat after 5h of prolonged wakefulness

Pierre Magistretti, Bernard Lanz, Rolf Gruetter, Jean-Marie Petit, Hanne Frenkel

Although glycogen (Glyc) is the main carbohydrate storage component, the role of Glyc in the brain during prolonged wakefulness is not clear. The aim of this study was to determine brain Glyc concentration ([]) and turnover time (tau) in euglycemic conscio ...

Elsevier2009

Selective Resonance Suppression H-1-[C-13] NMR Spectroscopy With Asymmetric Adiabatic RF Pulses

Rolf Gruetter, Lijing Xin, Hanne Frenkel

Despite obvious improvements in spectral resolution at high magnetic field, the detection of C-13 labeling by H-1-[C-13] NMR spectroscopy remains hampered by spectral overlap, such as in the spectral region of H-1 resonances bound to C3 of glutamate (Glu) ...

Wiley-Blackwell2009

Alteration of brain glycogen turnover in the awake rat

Pierre Magistretti, Bernard Lanz, Rolf Gruetter, Jean-Marie Petit, Hanne Frenkel

Nature Publishing Group2009

Time-resolved measurement of rat brain glycogen absolute concentration in vivo

Sabrina Laus, Rolf Gruetter, Ruud van Heeswijk, Lijing Xin, Hanne Frenkel, Hongxia Lei

Wiley-Blackwell2009

Biochemical evidence for a significant blood-brain barrier for glucose in hypothalamus using the reversible Michaelis-Menten model

Rolf Gruetter, Hanne Frenkel, Hongxia Lei, Carole Poitry-Yamate

Wiley-Blackwell2009

Mapping glucose and lactate concentrations with microliter resolution in rat brain using short-echo-time spectroscopic imaging

Rolf Gruetter, Hanne Frenkel, Cristina Ramona Cudalbu

2009

BISEP-based, Ultra-short TE 1H–[13C] NMR Spectroscopy of the Rat Brain at 14.1 T

Bernard Lanz, Rolf Gruetter, Lijing Xin, Hanne Frenkel

2009

Comparison of glutamate and glutamine quantitation in rat brain by 1H-[13C] NMR Spectroscopy at 9.4 T and 14.1 T

Rolf Gruetter, Lijing Xin, Hanne Frenkel

2009

Non-invasive quantification of brain glycogen absolute concentration

Sabrina Laus, Rolf Gruetter, Ruud van Heeswijk, Lijing Xin, Hanne Frenkel, Hongxia Lei

The only currently available method to measure brain glycogen in vivo is C-13 NMR spectroscopy. Incorporation of C-13-labeled glucose (Glc) is necessary to allow glycogen measurement, but might be affected by turnover changes. Our aim was to measure glycog ...

Wiley-Blackwell2008

Localized 1H[13C] NMR Measurement of N-acetyl-aspartate Turnover in Rat Brain

Rolf Gruetter, Lijing Xin, Hanne Frenkel

2008

Glucose and glycogen content in rat hypothalamus at euglycemia and hypoglycemia

Rolf Gruetter, Hanne Frenkel, Hongxia Lei, Carole Poitry-Yamate

Wiley-Blackwell2007

13C-edited 1H NMR Spectroscopy with Selective Resonance Suppression Using Asymmetric Adiabatic RF Pulses

Rolf Gruetter, Lijing Xin, Hanne Frenkel

2007

Localized short-echo-time proton MR spectroscopy with full signal-intensity acquisition

Rolf Gruetter, Giulio Gambarota, Hanne Frenkel

We developed a short-echo-time (TE) sequence for proton localized spectroscopy by combining a 1D add-subtract scheme with a doubly slice-selective spin-echo (SE) sequence. The sequence preserves the full magnetization available from the selected volume of ...

Wiley-Blackwell2006