Publications de Alkiviadis Tsamis

A constituent-based model of age-related changes in conduit arteries

Alexander Rachev, Nikolaos Stergiopoulos, Alkiviadis Tsamis

Tsamis A, Rachev A, Stergiopulos N. A constituent-based model of age-related changes in conduit arteries. Am J Physiol Heart Circ Physiol 301: H1286-H1301, 2011. First published July 1, 2011; doi: 10.1152/ajpheart.00570.2010.-In the present report, a const ...

2011

Arterial remodeling using a constituent-based approach

Alkiviadis Tsamis

This thesis is intended to contribute to the field of biomechanics of growth and remodeling of arteries. The work focuses particularly on growth and remodeling caused by sustained hypertension, increased blood flow, and ageing. A structure-based constituti ...

EPFL2010

A structure-based model of arterial remodeling in response to sustained hypertension

Alexander Rachev, Nikolaos Stergiopoulos, Alkiviadis Tsamis

A novel structure-based mathematical model of arterial remodeling in response to a sustained increase in pressure is proposed. The model includes two major aspects of remodeling in a healthy matured vessel. First, the deviation of the wall stress and flow- ...

2009

Arterial remodeling in response to increased blood flow using a constituent-based model

Nikolaos Stergiopoulos, Alkiviadis Tsamis

Previous theoretical models of arterial remodeling in response to changes in blood flow were based on the assumption that material properties of the arterial wall remain unchanged during the remodeling process. According to experimental findings, however, ...

2009

A Structure-Based Model Of Arterial Remodeling In Response To Sustained Hypertension

Alexander Rachev, Nikolaos Stergiopoulos, Alkiviadis Tsamis

2009

On the in-series and in-parallel contribution of elastin assessed by a structure-based biomechanical model of the arterial wall

Nikolaos Stergiopoulos, Sylvain Roy, Gilles Prod'Hom, Alkiviadis Tsamis

Earlier experimental work on decellularized arteries revealed the existence of significant residual stresses within the arterial wall, which are released upon chemical removal of vascular smooth muscle in normal arteries causing substantial radial expansio ...

2008

Arterial remodeling in response to hypertension using a constituent-based model

Nikolaos Stergiopoulos, Alkiviadis Tsamis

Hypertension-induced arterial remodeling has been previously modeled using stress-driven remodeling rate equations in terms of global geometrical adaptation (Rachev A, Stergiopulos N, Meister JJ. Theoretical study of dynamics of arterial wall remodeling in ...

2007